ID B9XIH2_PEDPL Unreviewed; 634 AA.
AC B9XIH2;
DT 14-APR-2009, integrated into UniProtKB/TrEMBL.
DT 14-APR-2009, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Peptidoglycan glycosyltransferase {ECO:0000313|EMBL:EEF60433.1};
DE EC=2.4.1.129 {ECO:0000313|EMBL:EEF60433.1};
DE Flags: Precursor;
GN ORFNames=Cflav_PD3403 {ECO:0000313|EMBL:EEF60433.1};
OS Pedosphaera parvula (strain Ellin514).
OC Bacteria; Verrucomicrobiota; Verrucomicrobiae; Limisphaerales; Pedosphaera.
OX NCBI_TaxID=320771 {ECO:0000313|EMBL:EEF60433.1, ECO:0000313|Proteomes:UP000003688};
RN [1] {ECO:0000313|EMBL:EEF60433.1, ECO:0000313|Proteomes:UP000003688}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ellin514 {ECO:0000313|EMBL:EEF60433.1,
RC ECO:0000313|Proteomes:UP000003688};
RX PubMed=21460084; DOI=10.1128/JB.00299-11;
RA Kant R., van Passel M.W., Sangwan P., Palva A., Lucas S., Copeland A.,
RA Lapidus A., Glavina Del Rio T., Dalin E., Tice H., Bruce D., Goodwin L.,
RA Pitluck S., Chertkov O., Larimer F.W., Land M.L., Hauser L., Brettin T.S.,
RA Detter J.C., Han S., de Vos W.M., Janssen P.H., Smidt H.;
RT "Genome sequence of 'Pedosphaera parvula' Ellin514, an aerobic
RT Verrucomicrobial isolate from pasture soil.";
RL J. Bacteriol. 193:2900-2901(2011).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEF60433.1}.
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DR EMBL; ABOX02000017; EEF60433.1; -; Genomic_DNA.
DR AlphaFoldDB; B9XIH2; -.
DR STRING; 320771.Cflav_PD3403; -.
DR OrthoDB; 9770103at2; -.
DR Proteomes; UP000003688; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0008955; F:peptidoglycan glycosyltransferase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Glycosyltransferase {ECO:0000313|EMBL:EEF60433.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000003688};
KW Transferase {ECO:0000313|EMBL:EEF60433.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 53..246
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 293..593
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 634 AA; 69347 MW; 13772ED48347CF05 CRC64;
MAKRLQYRRL LMLALLLGAA FAGLGYRLVD LQVLRHEVLE TKARENTQHV YQLEPRRGNI
LDSKGNLLAT SIFVKTVCAD PALIGNRQAE VAHVVAPILG LNEAELTQRL MPRIGRDEKG
ETRTNHYVVL KRKVSSDDWQ KVQSAMSNAV FAGEENITSK KEKAFYRNLR AKAISTDPID
DQLRTYPNQS LASHVIGFTG IIERTNGVGR FLETIGIDGI ERMLDAKLKG VRGWRLTEVD
GQKREIVSLR EQDVEANDGL NAVLTIDSGL QHILESALAE GLQKESPAAI SGMIVRPKTG
EILAMAVLPS FDPNSPGGTA DARRNRLISD MNEPGSTFKI VVVSGALNDQ MVKLSDMFDC
EHGRFAFAGR TLHDHAQYGT LSTEGIITKS SNIGAAKIGI RMGEAKLYQY MKDFGFGDKT
GILLPGEIGG WVHPVKDWTK VSIAQIPMGQ GVAITSMQMC MAMSAIANKG VLMKPILLDR
LEDNGGNVVA RYAPQPVRRV ISEEAAREMI EALKTVPTKD GTAPKAAMEH YTVAGKTGTA
QKVPYHLNKF YASFIGFFPA DNAEICIYVS MDDPKGHLHQ GGQVAAPVFK EIAEKAANYL
NIRPDRDVEI GPPNVIVPAD AGQQQQKTVA SKTL
//
