ID BEV1G_BETPN Reviewed; 160 AA.
AC P43180;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 27-MAR-2024, entry version 85.
DE RecName: Full=Major pollen allergen Bet v 1-G;
DE AltName: Full=Allergen Bet v I-G;
DE AltName: Allergen=Bet v 1-G;
GN Name=BETV1G;
OS Betula pendula (European white birch) (Betula verrucosa).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fagales; Betulaceae; Betula.
OX NCBI_TaxID=3505;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND PARTIAL PROTEIN SEQUENCE.
RC TISSUE=Pollen;
RX PubMed=7852325; DOI=10.1074/jbc.270.6.2607;
RA Swoboda I., Jilek A., Ferreira F., Engel E., Hoffman-Sommergruber K.,
RA Scheiner O., Kraft D., Breiteneder H., Pittenauer E., Schmid E.,
RA Vicente O., Heberle-Bors E., Ahorn H., Breitenbach M.;
RT "Isoforms of Bet v 1, the major birch pollen allergen, analyzed by liquid
RT chromatography, mass spectrometry, and cDNA cloning.";
RL J. Biol. Chem. 270:2607-2613(1995).
CC -!- FUNCTION: May be a general steroid carrier protein. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm.
CC -!- ALLERGEN: Causes an allergic reaction in human. Is a cause of type I
CC allergic reactions in Europe, North America and USSR.
CC -!- SIMILARITY: Belongs to the BetVI family. {ECO:0000305}.
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DR EMBL; X77269; CAA54485.1; -; mRNA.
DR PIR; F55699; F55699.
DR AlphaFoldDB; P43180; -.
DR SMR; P43180; -.
DR Allergome; 100; Bet v 1.0105.
DR Allergome; 89; Bet v 1.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0010427; F:abscisic acid binding; IEA:InterPro.
DR GO; GO:0004864; F:protein phosphatase inhibitor activity; IEA:InterPro.
DR GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR GO; GO:0009738; P:abscisic acid-activated signaling pathway; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0009607; P:response to biotic stimulus; IEA:UniProtKB-KW.
DR CDD; cd07816; Bet_v1-like; 1.
DR Gene3D; 3.30.530.20; -; 1.
DR InterPro; IPR000916; Bet_v_I/MLP.
DR InterPro; IPR024949; Bet_v_I_allergen.
DR InterPro; IPR023393; START-like_dom_sf.
DR PANTHER; PTHR31213:SF221; BET V I_MAJOR LATEX PROTEIN DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR31213; OS03G0300400 PROTEIN-RELATED; 1.
DR Pfam; PF00407; Bet_v_1; 1.
DR PRINTS; PR00634; BETALLERGEN.
DR SMART; SM01037; Bet_v_1; 1.
DR SUPFAM; SSF55961; Bet v1-like; 1.
DR PROSITE; PS00451; PATHOGENESIS_BETVI; 1.
PE 1: Evidence at protein level;
KW Allergen; Cytoplasm; Direct protein sequencing;
KW Pathogenesis-related protein; Plant defense.
FT INIT_MET 1
FT /note="Removed"
FT CHAIN 2..160
FT /note="Major pollen allergen Bet v 1-G"
FT /id="PRO_0000154180"
FT BINDING 55
FT /ligand="brassinolide"
FT /ligand_id="ChEBI:CHEBI:28277"
FT /evidence="ECO:0000250|UniProtKB:P43185"
FT BINDING 82
FT /ligand="brassinolide"
FT /ligand_id="ChEBI:CHEBI:28277"
FT /evidence="ECO:0000250|UniProtKB:P43185"
FT BINDING 84
FT /ligand="brassinolide"
FT /ligand_id="ChEBI:CHEBI:28277"
FT /evidence="ECO:0000250|UniProtKB:P43185"
FT BINDING 101
FT /ligand="brassinolide"
FT /ligand_id="ChEBI:CHEBI:28277"
FT /evidence="ECO:0000250|UniProtKB:P43185"
SQ SEQUENCE 160 AA; 17551 MW; 44FB26D53E44849B CRC64;
MGVFNYESET TSVIPAARLF KAFILEGDNL IPKVAPQAIS SVENIEGNGG PGTIKKINFP
EGFPFKYVKD RVDEVDHTNF KYNYSVIEGG PVGDTLEKIS NEIKIVATPD GGCVLKISNK
YHTKGNHEVK AEQVKASKEM GETLLRAVES YLLAHSDAYN
//
