ID   C0C2J3_9FIRM            Unreviewed;       318 AA.
AC   C0C2J3;
DT   05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   05-MAY-2009, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   SubName: Full=Transketolase, C-terminal domain protein {ECO:0000313|EMBL:EEG73617.1};
GN   ORFNames=CLOHYLEM_06299 {ECO:0000313|EMBL:EEG73617.1};
OS   [Clostridium] hylemonae DSM 15053.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=553973 {ECO:0000313|EMBL:EEG73617.1, ECO:0000313|Proteomes:UP000004893};
RN   [1] {ECO:0000313|EMBL:EEG73617.1, ECO:0000313|Proteomes:UP000004893}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15053 {ECO:0000313|EMBL:EEG73617.1,
RC   ECO:0000313|Proteomes:UP000004893};
RA   Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA   Gordon J.;
RT   "Draft genome sequence of Clostridium hylemonae (DSM 15053).";
RL   Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EEG73617.1, ECO:0000313|Proteomes:UP000004893}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15053 {ECO:0000313|EMBL:EEG73617.1,
RC   ECO:0000313|Proteomes:UP000004893};
RA   Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA   Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL   Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EEG73617.1}.
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DR   EMBL; ABYI02000023; EEG73617.1; -; Genomic_DNA.
DR   RefSeq; WP_006443654.1; NZ_GG657759.1.
DR   AlphaFoldDB; C0C2J3; -.
DR   STRING; 553973.CLOHYLEM_06299; -.
DR   eggNOG; COG3958; Bacteria.
DR   HOGENOM; CLU_009227_1_1_9; -.
DR   OrthoDB; 8732661at2; -.
DR   Proteomes; UP000004893; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   CDD; cd07033; TPP_PYR_DXS_TK_like; 1.
DR   Gene3D; 3.40.50.920; -; 1.
DR   Gene3D; 3.40.50.970; -; 1.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR   InterPro; IPR033248; Transketolase_C.
DR   PANTHER; PTHR43825; PYRUVATE DEHYDROGENASE E1 COMPONENT; 1.
DR   PANTHER; PTHR43825:SF1; TRANSKETOLASE-LIKE PYRIMIDINE-BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF02779; Transket_pyr; 1.
DR   Pfam; PF02780; Transketolase_C; 1.
DR   SMART; SM00861; Transket_pyr; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR   SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE   4: Predicted;
FT   DOMAIN          11..176
FT                   /note="Transketolase-like pyrimidine-binding"
FT                   /evidence="ECO:0000259|SMART:SM00861"
SQ   SEQUENCE   318 AA;  34077 MW;  9187AE618A5E7295 CRC64;
     MNEAVQKERS LISKEIFGKV ITALGKEKEN IVVCDTDLMR CFGTKAFSEQ FPSRHINFGI
     AEQNCMAAAA GLALSGKNVF ASSFANFASK RACDQVSIAV AYNRANVKVC GLYAGLTAEK
     NGGTHIGVED VALMRSIPDL CVIEPADTYE LEAVTRFLAE YEGPVYFRQP KMYIRSVYEE
     VPDFELGKGV TLRGGSDAAV IACGITAGIA VDAAQLLQKE GIDVRVINMP TIKPLDEEII
     QEAAVQTGRI VTCENHSVIG GLGSAAAEVL AGMKEKAVLH RMGIQDTFGV TASLDYQLKK
     NGLTAENIAA EIKGMLAD
//