ID   C0EHM8_9FIRM            Unreviewed;       193 AA.
AC   C0EHM8;
DT   05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   05-MAY-2009, sequence version 1.
DT   27-MAR-2024, entry version 61.
DE   SubName: Full=Transcriptional regulator, TetR family {ECO:0000313|EMBL:EEG29046.1};
GN   ORFNames=CLOSTMETH_03373 {ECO:0000313|EMBL:EEG29046.1};
OS   [Clostridium] methylpentosum DSM 5476.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Oscillospiraceae incertae sedis.
OX   NCBI_TaxID=537013 {ECO:0000313|EMBL:EEG29046.1, ECO:0000313|Proteomes:UP000003340};
RN   [1] {ECO:0000313|EMBL:EEG29046.1, ECO:0000313|Proteomes:UP000003340}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 5476 {ECO:0000313|EMBL:EEG29046.1,
RC   ECO:0000313|Proteomes:UP000003340};
RA   Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA   Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL   Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EEG29046.1, ECO:0000313|Proteomes:UP000003340}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 5476 {ECO:0000313|EMBL:EEG29046.1,
RC   ECO:0000313|Proteomes:UP000003340};
RA   Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA   Gordon J.;
RT   "Draft genome sequence of Clostridium methylpentosum (DSM 5476).";
RL   Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EEG29046.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; ACEC01000118; EEG29046.1; -; Genomic_DNA.
DR   AlphaFoldDB; C0EHM8; -.
DR   STRING; 537013.CLOSTMETH_03373; -.
DR   eggNOG; COG1309; Bacteria.
DR   HOGENOM; CLU_069356_12_2_9; -.
DR   Proteomes; UP000003340; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001647; HTH_TetR.
DR   PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR   PANTHER; PTHR30055:SF164; TRANSCRIPTIONAL REPRESSOR MCE3R; 1.
DR   Pfam; PF00440; TetR_N; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   PROSITE; PS50977; HTH_TETR_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003340}.
FT   DOMAIN          2..63
FT                   /note="HTH tetR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50977"
FT   DNA_BIND        26..45
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ   SEQUENCE   193 AA;  21757 MW;  EB08DB47E61B4BB4 CRC64;
     MKDKKGDILR AALVCLGEGQ NPNEIKIAEI ARRAGVGKGT VYEYFTSKQE LFAESVLCFI
     SECLAKMQKA GGSGSFRERF FAVLKVLSGC LDNCRPLFYT VFLHQQFCSP EAEAAQRMLS
     RQPEVERELL LILDELLRQA EAEGLFPRRE EQDSLFAFSC VVGALCFAGC SPTKQDRDLL
     FEKCYQTFLK LNQ
//