ID C0FMS6_9FIRM Unreviewed; 596 AA.
AC C0FMS6;
DT 05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 05-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Creatinase {ECO:0000313|EMBL:EEG96010.1};
GN ORFNames=ROSEINA2194_00033 {ECO:0000313|EMBL:EEG96010.1};
OS Roseburia inulinivorans DSM 16841.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX NCBI_TaxID=622312 {ECO:0000313|EMBL:EEG96010.1, ECO:0000313|Proteomes:UP000003561};
RN [1] {ECO:0000313|EMBL:EEG96010.1, ECO:0000313|Proteomes:UP000003561}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16841 {ECO:0000313|EMBL:EEG96010.1,
RC ECO:0000313|Proteomes:UP000003561};
RA Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEG96010.1, ECO:0000313|Proteomes:UP000003561}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16841 {ECO:0000313|EMBL:EEG96010.1,
RC ECO:0000313|Proteomes:UP000003561};
RA Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA Gordon J.;
RT "Draft genome sequence of Roseburia inulinivorans (DSM 16841).";
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M24B family.
CC {ECO:0000256|ARBA:ARBA00008766}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEG96010.1}.
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DR EMBL; ACFY01000003; EEG96010.1; -; Genomic_DNA.
DR RefSeq; WP_007881931.1; NZ_JAJFOJ010000002.1.
DR AlphaFoldDB; C0FMS6; -.
DR GeneID; 75163412; -.
DR eggNOG; COG0006; Bacteria.
DR Proteomes; UP000003561; Unassembled WGS sequence.
DR GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR CDD; cd01085; APP; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 2.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR033740; Pept_M24B.
DR InterPro; IPR032416; Peptidase_M24_C.
DR PANTHER; PTHR43763; XAA-PRO AMINOPEPTIDASE 1; 1.
DR PANTHER; PTHR43763:SF6; XAA-PRO AMINOPEPTIDASE 1; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF16189; Creatinase_N_2; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR Pfam; PF16188; Peptidase_M24_C; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 2.
PE 3: Inferred from homology;
FT DOMAIN 5..123
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 310..527
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
FT DOMAIN 536..596
FT /note="Peptidase M24 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16188"
SQ SEQUENCE 596 AA; 67520 MW; 13660F9AD6C5AA54 CRC64;
MIPERLTALR EEMKRRSIDI YVVPTADFHE SEYVGEHFKA RKFITGFTGS AGTAVITLKE
AGLWTDGRYF VQAEKQLEGS TVTLYRMAEE GVPTVEEFVK DKLPQGGCIG FDGRTVNGAW
GEKFVAIAEE KKGSLFVGED LINLIWTDRP ELSKAPLFIL EEKYSGKSTA EKIKDVRAKM
AEEGADVHIL TSLCDIAWLL NIRGGDIQSV PVVLSYLVLT RDQCIWFLQE EVVDDTIRAY
LKENHIETRP YDDIYTYVPT IPESAVVLMN KSSVNYRICS ELNKNIQVIN KPNPTELMKA
VKNPVEVDNT RLAHVKDGVA VTKFMYWLKT NIGKIPMTEI SASDYLEARR REQENFIDLS
FTTISAYGAN AAMMHYSATP ESNTELKPEG FLLVDSGGHY YEGTTDITRT FVLGPISDEM
KQHFTAVCRS NMKLANAKFL YGACGLNLDI LARGPLWDMG IDYKCGTGHG VGYILNVHEG
PNGFRWKIVP ERHDSGVLEE GMITTDEPGV YLEGKYGIRT ENELVCRKAE KNEYGQFMEF
ENITYAPIDL DGIDPEQMSP REKQMLNDYH KKVYEVLSPY MTEEENEWLK KYTRAI
//
