ID   C0NJN6_AJECG            Unreviewed;       605 AA.
AC   C0NJN6;
DT   05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   05-MAY-2009, sequence version 1.
DT   27-MAR-2024, entry version 49.
DE   SubName: Full=Tubulin-specific chaperone E {ECO:0000313|EMBL:EEH08077.1};
GN   ORFNames=HCBG_03366 {ECO:0000313|EMBL:EEH08077.1};
OS   Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC 2432)
OS   (Darling's disease fungus) (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX   NCBI_TaxID=447093 {ECO:0000313|EMBL:EEH08077.1, ECO:0000313|Proteomes:UP000001631};
RN   [1] {ECO:0000313|Proteomes:UP000001631}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=G186AR / H82 / ATCC MYA-2454 / RMSCC 2432
RC   {ECO:0000313|Proteomes:UP000001631};
RA   Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Sil A., Goldman B.,
RA   Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A.,
RA   Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA   Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C., Jen D., Larson L.,
RA   Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T.,
RA   Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C.,
RA   Klein B., McEwen J.G., Puccia R., Goldman G.H., Felipe M.S., Nino-Vega G.,
RA   San-Blas G., Taylor J., Mendoza L., Galagan J.E., Nusbaum C., Birren B.W.;
RT   "The genome sequence of Ajellomyces capsulatus strain G186AR.";
RL   Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GG663366; EEH08077.1; -; Genomic_DNA.
DR   AlphaFoldDB; C0NJN6; -.
DR   STRING; 447093.C0NJN6; -.
DR   VEuPathDB; FungiDB:I7I50_06960; -.
DR   HOGENOM; CLU_017716_3_1_1; -.
DR   InParanoid; C0NJN6; -.
DR   OrthoDB; 11880at2759; -.
DR   Proteomes; UP000001631; Unassembled WGS sequence.
DR   Gene3D; 2.30.30.190; CAP Gly-rich-like domain; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR   InterPro; IPR036859; CAP-Gly_dom_sf.
DR   InterPro; IPR000938; CAP-Gly_domain.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   PANTHER; PTHR45973; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED; 1.
DR   Pfam; PF01302; CAP_GLY; 1.
DR   Pfam; PF13516; LRR_6; 1.
DR   SMART; SM01052; CAP_GLY; 1.
DR   SUPFAM; SSF74924; Cap-Gly domain; 1.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   PROSITE; PS50245; CAP_GLY_2; 1.
DR   PROSITE; PS51450; LRR; 1.
PE   4: Predicted;
KW   Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001631}.
FT   DOMAIN          22..68
FT                   /note="CAP-Gly"
FT                   /evidence="ECO:0000259|PROSITE:PS50245"
FT   REGION          543..570
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   605 AA;  68694 MW;  B2B3965CE83FD26B CRC64;
     MGISLGSRLS FEGGLCTVRY IGEVKGTKGQ WLGVEWDDST RGKHSGEHDG VKYFQCKSKH
     PTAGSFVRPT RQADRNLSFL QAANEKYVSE LEPVSSGHED LLSSKPIEIS GKIVEEVGFE
     KIRRLLAELQ ELRIVLLDGM RVYGVLAGEG SREEYENELK IIARTCPKIV ELDLSRNVLR
     RWTDVAAICE QLKLLKILKL NGNRFDEIGE NITLDGIAEL ALDETLMEWK EVAAVSKQFP
     SLRSLSVSGN EFTSLPCPIS STIQELILEY NGFESIHSIR QLASLSELKK LSLRGNMISR
     IGSDNPPTIP EKSNIVFSST LTSLDISFNK ISHWSFIDML PRVFPGLATL RVSDNPLYDQ
     PPAPSRVTNM PEYPMTVDEA YMLTLARLPR LETLNYSKIT DQDRNNGELY YLSLIRKELA
     ASPQSEENHI LELHPRYREL CSTYGEVEIN RETESSGSGI HPRSLAARLV TFNFYLPDRQ
     NQKPISQKPD MTASAEYSTN IPKSFDVYRI KALVARHFSL SPLRFKLVWE TDEWDPIEES
     WADDDEWDSS DEIDEPGPQH GSSALKHEDG KKLIRREEEL VNSTREVGFW FTNETRQVRV
     RIESF
//