ID   C0NNX8_AJECG            Unreviewed;       592 AA.
AC   C0NNX8;
DT   05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   05-MAY-2009, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   RecName: Full=OTU domain-containing protein {ECO:0000259|PROSITE:PS50802};
GN   ORFNames=HCBG_04858 {ECO:0000313|EMBL:EEH06638.1};
OS   Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC 2432)
OS   (Darling's disease fungus) (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX   NCBI_TaxID=447093 {ECO:0000313|EMBL:EEH06638.1, ECO:0000313|Proteomes:UP000001631};
RN   [1] {ECO:0000313|Proteomes:UP000001631}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=G186AR / H82 / ATCC MYA-2454 / RMSCC 2432
RC   {ECO:0000313|Proteomes:UP000001631};
RA   Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Sil A., Goldman B.,
RA   Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A.,
RA   Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA   Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C., Jen D., Larson L.,
RA   Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T.,
RA   Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C.,
RA   Klein B., McEwen J.G., Puccia R., Goldman G.H., Felipe M.S., Nino-Vega G.,
RA   San-Blas G., Taylor J., Mendoza L., Galagan J.E., Nusbaum C., Birren B.W.;
RT   "The genome sequence of Ajellomyces capsulatus strain G186AR.";
RL   Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GG663368; EEH06638.1; -; Genomic_DNA.
DR   AlphaFoldDB; C0NNX8; -.
DR   STRING; 447093.C0NNX8; -.
DR   VEuPathDB; FungiDB:I7I50_05046; -.
DR   HOGENOM; CLU_460752_0_0_1; -.
DR   InParanoid; C0NNX8; -.
DR   OrthoDB; 597214at2759; -.
DR   Proteomes; UP000001631; Unassembled WGS sequence.
DR   GO; GO:0019538; P:protein metabolic process; IEA:UniProt.
DR   CDD; cd22756; OTU_OTUD3-like; 1.
DR   Gene3D; 3.90.70.80; -; 1.
DR   InterPro; IPR003323; OTU_dom.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   PANTHER; PTHR12419; OTU DOMAIN CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR12419:SF7; OTU DOMAIN-CONTAINING PROTEIN 3; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
DR   PROSITE; PS50802; OTU; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001631}.
FT   DOMAIN          66..215
FT                   /note="OTU"
FT                   /evidence="ECO:0000259|PROSITE:PS50802"
FT   REGION          1..36
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          317..399
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          426..592
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        317..373
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        374..393
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        426..453
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        454..491
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        496..532
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        551..592
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   592 AA;  65177 MW;  66DDDEAA8700A56C CRC64;
     MANLPPPSNP RIVPIMARRK SHSSGPAGNR TSPPEDSAMK MHLEMAMAGM PSKSSLKLGC
     LDYFNLYAMP ILGDDQLYGS VDRHIEIRER LVQHMRDNAD YFRDFTADVG GERRAPRRSA
     AQASRLAYTN VDRAATAEGQ AAKFKLMLNE MKGQNAWGGS PEIQAFCQAY GLDVLVYSED
     GVQRFQNFFA EADPNRGVIH LAFHSFQHYS SVRNLDGPHV GLPKLPERIK AADLIYRKIT
     SKEPMIDQKI NPENIPSESQ NPTVTHPADM HWMITIFGQR VPANDDESIR AMIGECSPNI
     TAALNRLVEN KNRALPRSSI PFSTSLSSTT TSNSVPTPCS GGSRPKSSST MNTSSGAVQG
     SSSRSSSRHS VTSKRSANDS DLDEEDGTVR TATRRSRGRC RKRRMLEDVT VDILGNRSEV
     VAIEVNHNND DEEGDDHNKY NSSNRDNDHH DGTNRNGNLN AGQGNLDVGI GTSSRTGTST
     ATRTLTGTRT LSPEPIAKEH YTKQKQKQKQ KQTDGVIRSI ENDHDDHDGD PCSVRTLSPS
     ASQGSEATNS KEEDDIDDEY VDADADEDED EDEDGDGDDD ADSDYKDEED DE
//