ID   C0NTF9_AJECG            Unreviewed;       664 AA.
AC   C0NTF9;
DT   05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   05-MAY-2009, sequence version 1.
DT   27-MAR-2024, entry version 48.
DE   SubName: Full=Aromatic amino acid aminotransferase {ECO:0000313|EMBL:EEH05320.1};
GN   ORFNames=HCBG_06439 {ECO:0000313|EMBL:EEH05320.1};
OS   Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC 2432)
OS   (Darling's disease fungus) (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX   NCBI_TaxID=447093 {ECO:0000313|EMBL:EEH05320.1, ECO:0000313|Proteomes:UP000001631};
RN   [1] {ECO:0000313|Proteomes:UP000001631}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=G186AR / H82 / ATCC MYA-2454 / RMSCC 2432
RC   {ECO:0000313|Proteomes:UP000001631};
RA   Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Sil A., Goldman B.,
RA   Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A.,
RA   Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA   Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C., Jen D., Larson L.,
RA   Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T.,
RA   Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C.,
RA   Klein B., McEwen J.G., Puccia R., Goldman G.H., Felipe M.S., Nino-Vega G.,
RA   San-Blas G., Taylor J., Mendoza L., Galagan J.E., Nusbaum C., Birren B.W.;
RT   "The genome sequence of Ajellomyces capsulatus strain G186AR.";
RL   Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the class-I pyridoxal-phosphate-dependent
CC       aminotransferase family. {ECO:0000256|ARBA:ARBA00007441}.
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DR   EMBL; GG663371; EEH05320.1; -; Genomic_DNA.
DR   AlphaFoldDB; C0NTF9; -.
DR   STRING; 447093.C0NTF9; -.
DR   VEuPathDB; FungiDB:I7I50_05661; -.
DR   HOGENOM; CLU_017584_0_5_1; -.
DR   InParanoid; C0NTF9; -.
DR   OrthoDB; 5486605at2759; -.
DR   Proteomes; UP000001631; Unassembled WGS sequence.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   CDD; cd00609; AAT_like; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR004839; Aminotransferase_I/II.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   PANTHER; PTHR42790; AMINOTRANSFERASE; 1.
DR   PANTHER; PTHR42790:SF1; AROMATIC AMINO ACID AMINOTRANSFERASE, HYPOTHETICAL (EUROFUNG); 1.
DR   Pfam; PF00155; Aminotran_1_2; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
KW   Aminotransferase {ECO:0000313|EMBL:EEH05320.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001631};
KW   Transferase {ECO:0000313|EMBL:EEH05320.1}.
FT   DOMAIN          156..442
FT                   /note="Aminotransferase class I/classII"
FT                   /evidence="ECO:0000259|Pfam:PF00155"
FT   REGION          339..365
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          512..535
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        343..365
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   664 AA;  74041 MW;  B94C5A8816E231A3 CRC64;
     MAANKCAIGS LIPKFSYGHQ QDTNLKIKYP NRKPTEAKAP KNEYPPKLAP VDLSHHFSVV
     ARNRVGSDVK KFYKYFAIPG IHNLAGGLPH PSYFPYDTLE AAVALPTRID PSTADGPSTV
     AEGDEILVST LPPTARLTIP KESNNTNPTT RIDLTTALQY GTAQGYPPLF SFIRQFVREN
     LHPNIPYTGG PEVILTCGAT DGFSKTIEAL TNVWDENRDW IRDRECILCE EFVYMNAIQT
     VKPRGINVVT VAMDSDGMMV DGDRGLKHIL ESWDFSRGKR PHLMYTVTIG QNPTGTVLPL
     PRRRDLYSLC QKYDIIIVED DPYWHLQYPS AGPELEAHFR GSSSLKSRPQ PHSNHADTTL
     APNYNTHGKT SGYPFLDSLI PSYLSIDTDG RVIRLDTFSK IIAPGCRLGW LTAQPKIVER
     ILYITETSTQ QPSGFVQAMV AGLIMGGGGG GKKDELDRVG EEGCSGDAAG GRQSGTWKME
     GWVRWLEGLR DGYEWRMRTM CTILEEGRSI IEQTPSAGTS RSHHSYYDSD SDEDDEDDWQ
     LLRKTPLYSF QFPRGGMFVW VRMCFETHQL WSCEGVSAER LSAALWKHLT KKPYLCLVAP
     GAMFNPAGGG NGQRGGSDES FRYFRLCFAP MQEGDVAVSA KGFVEGCRNF WLRGVLEDDD
     DDDM
//