ID   C0NXM8_AJECG            Unreviewed;       583 AA.
AC   C0NXM8;
DT   05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   05-MAY-2009, sequence version 1.
DT   27-MAR-2024, entry version 57.
DE   SubName: Full=Pre-mRNA-splicing factor {ECO:0000313|EMBL:EEH04094.1};
GN   ORFNames=HCBG_08220 {ECO:0000313|EMBL:EEH04094.1};
OS   Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC 2432)
OS   (Darling's disease fungus) (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX   NCBI_TaxID=447093 {ECO:0000313|EMBL:EEH04094.1, ECO:0000313|Proteomes:UP000001631};
RN   [1] {ECO:0000313|Proteomes:UP000001631}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=G186AR / H82 / ATCC MYA-2454 / RMSCC 2432
RC   {ECO:0000313|Proteomes:UP000001631};
RA   Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Sil A., Goldman B.,
RA   Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A.,
RA   Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA   Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C., Jen D., Larson L.,
RA   Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T.,
RA   Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C.,
RA   Klein B., McEwen J.G., Puccia R., Goldman G.H., Felipe M.S., Nino-Vega G.,
RA   San-Blas G., Taylor J., Mendoza L., Galagan J.E., Nusbaum C., Birren B.W.;
RT   "The genome sequence of Ajellomyces capsulatus strain G186AR.";
RL   Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GG663375; EEH04094.1; -; Genomic_DNA.
DR   AlphaFoldDB; C0NXM8; -.
DR   STRING; 447093.C0NXM8; -.
DR   VEuPathDB; FungiDB:I7I50_08540; -.
DR   HOGENOM; CLU_022571_2_1_1; -.
DR   InParanoid; C0NXM8; -.
DR   OrthoDB; 148364at2759; -.
DR   Proteomes; UP000001631; Unassembled WGS sequence.
DR   GO; GO:0071013; C:catalytic step 2 spliceosome; IEA:InterPro.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR   CDD; cd00200; WD40; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR032847; PRPF17.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR43979; PRE-MRNA-PROCESSING FACTOR 17; 1.
DR   PANTHER; PTHR43979:SF1; PRE-MRNA-PROCESSING FACTOR 17; 1.
DR   Pfam; PF00400; WD40; 5.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 6.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 4.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 4.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001631};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW   ProRule:PRU00221}.
FT   REPEAT          285..327
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          329..370
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          415..447
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          557..583
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REGION          1..32
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..25
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   583 AA;  64863 MW;  E0E55B7C36A5D935 CRC64;
     MASLLGANYE SSSDDEVQQN LPVKSTPAPV PAPGIVAAPD VSIEDSSRLQ LMLAKSTDTA
     LTYNATYDDL SRPTLGPENP FRSAHGGNAL KRKNVLTGHA EETLISEATF NSQHRTFQAF
     GYTQDPSVPG AFVGDLEAAA RLGGKNVVQM RPSKEASAAL RRKRQKKGDS SIVEGEGAYL
     GPWARYEDDD LMYEEELDLA GRELASDEEY IDEAIVPSNV PAMDKKATAY KEDTSHTETT
     EFHGSEQFDY QGRTYMHVPQ DLDIDLKKEV GSIKNYVPKK LVHTWKSHTK PITSLRFFPN
     SGHLLLSSSA DSKIKIWDAH HSRELLRTYS GHSNAVTDTT FHPTGTTFLS GSYDRQIKLW
     DTEYGKCISR FSTGKTPHVI RFNPDPDHSH EFLAGMSDKK IIQFDTRTGA ITQEYDHHLA
     AVNTLTFVDN NRRFISTSDD KSLRAWEYNI PVPIKFIAEP YLYALVRAAP HPNGKYVAFQ
     SGDNQIVVYA STDKFRQNRK KSFRGHNNAG YAIDVAISPD GQFVTSGDSG GYVCFWDWKT
     GKMWHKIMAG GKEGAAITCV EWHPQETSKV ATAGLEGVIK YWD
//