ID   C0PUV0_SALSA            Unreviewed;       906 AA.
AC   C0PUV0;
DT   05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   05-MAY-2009, sequence version 1.
DT   27-MAR-2024, entry version 52.
DE   SubName: Full=Superkiller viralicidic activity 2-like 2 {ECO:0000313|EMBL:ACN58736.1};
DE   Flags: Fragment;
GN   Name=SK2L2 {ECO:0000313|EMBL:ACN58736.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|EMBL:ACN58736.1};
RN   [1] {ECO:0000313|EMBL:ACN58736.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Brain {ECO:0000313|EMBL:ACN58736.1};
RG   cGRASP (B.F. Koop & W.S. Davidson);
RA   Leong J., von Schalburg K., Cooper G., Moore R., Holt R., Davidson W.S.,
RA   Koop B.F.;
RT   "Salmo salar full-length cDNAs.";
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; BT072786; ACN58736.1; -; mRNA.
DR   AlphaFoldDB; C0PUV0; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR   GO; GO:0006401; P:RNA catabolic process; IEA:InterPro.
DR   CDD; cd18024; DEXHc_Mtr4-like; 1.
DR   CDD; cd13154; KOW_Mtr4; 1.
DR   CDD; cd18795; SF2_C_Ski2; 1.
DR   Gene3D; 1.10.3380.30; -; 2.
DR   Gene3D; 2.40.30.300; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR048392; MTR4-like_stalk.
DR   InterPro; IPR025696; MTR4_beta-barrel.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR016438; SKI2-like.
DR   InterPro; IPR012961; Ski2/MTR4_C.
DR   PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR   PANTHER; PTHR12131:SF7; EXOSOME RNA HELICASE MTR4; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF08148; DSHCT; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF21408; MTR4-like_stalk; 1.
DR   Pfam; PF13234; MTR4_beta-barrel; 1.
DR   PIRSF; PIRSF005198; Antiviral_helicase_SKI2; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM01142; DSHCT; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT   DOMAIN          6..162
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          269..441
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          210..235
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ACN58736.1"
SQ   SEQUENCE   906 AA;  102474 MW;  1E7A3263CB0A333E CRC64;
     FQREAILCID NNQSVLVSAH TSAGKTVCAE YAIALALREK QRVIFTSPIK ALSNQKYREM
     YEEFQDVGLM TGDVTINPTA SCLIMTTEIL RSMLYRGSEV MREVAWVIFD EIHYMRDAER
     GVVWEETIIL LPDNVHYVFL SATIPNAKQF AEWICHLHKQ PCHVVYTDFR PTPLQHYIFP
     AGGDGLHLVV DENGEFREDN FNTAMQVLRD TGDSGGSSGG SKWDPKGRKG GTRGPSNVFK
     IVKMIMERNF QPVIIFSFSK KECEAYALQV SKLDFNTDEE KKLVEEVFNN AIDCLSDDDK
     KLPQVEHVLP LLKRGIGIHH GGLLPILKET IEILFSEGLL KALFATETFA MGINMPARTV
     LFTNARKFDG KDFRWITSGE YIQMSGRAGR RGMDERGIVI FMADEKMSPA VGKQLLKGSA
     DPLNSAFHLT YNMVLNLLRV EEINPEYMLE KSFYQFQHYR AVPGVVENMA KLEEMYNAIE
     IPNEESVVTY YKIRQQLAKL SKEIEEFIHK PKYCLPFLQP GRLVKVKNED ADFGWGVVVN
     FSKKSNVKAI TGDADPLYVV EVLVHCSKES VKNTATEAAK PAAAGEKGEM QVVPVMLHLL
     TSISSVRLYS PKDLRPYDNR QSMLKSIQEV QKRFPDGVPL LDPIDDMGIK DPGLKKVIQK
     VEAFEHRMYS HPMHSDPSLE AVYSLCERKA LIAGDIKGAK RELKKARTVL QMDELKCRKR
     VLRRLGFASS SDVIEMKGRV ACEISSADEL LLTEMVFNGL FNDLSAEQVT ALLSVFVFQE
     NVNEMPKLTE QLAGPLRQMQ ECAKRVAKVS AEAKLEVDED TYLDKFKPHL MDVVYTWANG
     STFAQICKMT DVFEGSIIRC MRRLEELLRQ MCQAAKAIGN TELENKFAEG ITKIKRDIVF
     AASLYL
//