ID   C0Q3X0_SALPC            Unreviewed;      1300 AA.
AC   C0Q3X0;
DT   05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   05-MAY-2009, sequence version 1.
DT   27-MAR-2024, entry version 82.
DE   SubName: Full=ATP-dependent helicase HrpA {ECO:0000313|EMBL:ACN46225.1};
GN   Name=hrpA {ECO:0000313|EMBL:ACN46225.1};
GN   OrderedLocusNames=SPC_2094 {ECO:0000313|EMBL:ACN46225.1};
OS   Salmonella paratyphi C (strain RKS4594).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=476213 {ECO:0000313|EMBL:ACN46225.1, ECO:0000313|Proteomes:UP000001599};
RN   [1] {ECO:0000313|EMBL:ACN46225.1, ECO:0000313|Proteomes:UP000001599}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RKS4594 {ECO:0000313|EMBL:ACN46225.1,
RC   ECO:0000313|Proteomes:UP000001599};
RX   PubMed=19229335; DOI=10.1371/journal.pone.0004510;
RA   Liu W.-Q., Feng Y., Wang Y., Zou Q.-H., Chen F., Guo J.-T., Peng Y.-H.,
RA   Jin Y., Li Y.-G., Hu S.-N., Johnston R.N., Liu G.-R., Liu S.-L.;
RT   "Salmonella paratyphi C: genetic divergence from Salmonella choleraesuis
RT   and pathogenic convergence with Salmonella typhi.";
RL   PLoS ONE 4:E4510-E4510(2009).
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DR   EMBL; CP000857; ACN46225.1; -; Genomic_DNA.
DR   RefSeq; WP_012664575.1; NC_012125.1.
DR   KEGG; sei:SPC_2094; -.
DR   HOGENOM; CLU_001832_3_3_6; -.
DR   Proteomes; UP000001599; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR   CDD; cd17989; DEXHc_HrpA; 1.
DR   CDD; cd18791; SF2_C_RHA; 1.
DR   Gene3D; 1.20.120.1080; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR048333; HA2_WH.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR024590; HrpA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010222; RNA_helicase_HrpA.
DR   NCBIfam; TIGR01967; DEAH_box_HrpA; 1.
DR   PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR   PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF11898; DUF3418; 1.
DR   Pfam; PF21010; HA2_C; 1.
DR   Pfam; PF04408; HA2_N; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF07717; OB_NTP_bind; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00847; HA2; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000313|EMBL:ACN46225.1};
KW   Hydrolase {ECO:0000313|EMBL:ACN46225.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          87..250
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          274..444
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   1300 AA;  148791 MW;  10A69367F47B275C CRC64;
     MTEQSTLTLQ VLQQRLDALM LRDKQRFARR LHGVKKVKNP DAQQAIFQTM AKEIEQAAAQ
     VALREAARPS ITYPQNLPVS QKKQDILEAI RDHQVVIVAG ETGSGKTTQL PKICMELGRG
     IKGLIGHTQP RRLAARTVAN RIAEELQTEP GGCIGYKVRF SDHVSSNTMV KLMTDGILLA
     EIQQDRLLMQ YDTIIIDEAH ERSLNIDFLL GYLKELLPRR PDLKVIITSA TIDPERFSRH
     FDNAPIIEVS GRTYPVEVRY RPIVEEADDT ERDQLQAIFD AVDELGRESP GDILIFMSGE
     REIRDTADAL NKLNLRHTEV LPLYARLSNS EQNRVFQSHS GRRIVLATNV AETSLTVPGI
     KYVIDPGTAR ISRYSYRTKV QRLPIEPISQ ASANQRKGRC GRVSEGICIR LYSEYDFLSR
     PEFTDPEILR TNLASVILQM TALGLGDIAA FPFVEAPDKR NIQDGVRLLE ELGAITADEQ
     QTAYKLTPLG RQLSQLPVDP RLARMVLEAQ KHGCVREAMI ITSALSIQDP RERPVDKQQA
     SDEKHRRFHD KESDFLAFVN LWNYLGEQQK ALSSNQFRRL CRTDYLNYLR VREWQDIYTQ
     LRQVVKELGI PVNSEPAEYR EIHVALLTGL LSHIGMKDAD KQEYTGARNA RFSIFPGSGL
     FKKPPKWTMV AELVETSRLW GRIAARIEPE WVEPVAQHLI KRSYSEPHWE RAQGAVMATE
     KVTVYGLPIV AARKVNYSQI DPALCRELFI RHALVEGDWQ TRHAFFRENL KLRAEVEELE
     HKSRRRDILV DDDTLFEFYD QRISHDVISA RHFDSWWKKI SRETPDLLNF EKSMLIKEGA
     EKISKLDYPN FWHQGNLKLR LSYQFEPGAD ADGVTVHIPL PLLNQVDESG FEWQIPGLRR
     ELVIALIKSL PKPVRRNFVP APNYAEAFLG RVTPLELPLL DALERELRRM TGVTVDREDW
     HWDQVPEHLK ITFRVVNDKN KKLQEGRSLA ELKNALKGKV QETLSAVADD GIEQSGLHIW
     SFGELPESYE QKRGNYKVKA WPALVDERDS VAIKLFDNPL EQQQAMWCGL RRLLLLNIPS
     PIKYLHEKLP NKAKLGLYFN PYGKVLELID DCIACGVDKL IDANGGPVWS EAGFTTLHEK
     VRAELNDTVV DIAKQVERIL TTVFNINKRL KGRVDMSMAL GLSDIKAQMS GLVYRGFVTG
     NGFKRLGDTL RYLQAIEKRL EKLAVDPHRD RAQMLKVESV QQAWQQWINK LPPARREDDD
     VKEIRWMIEE LRVSYFAQQL GTPYPISDKR ILQAMDQITA
//