ID C0QKB4_DESAH Unreviewed; 746 AA.
AC C0QKB4;
DT 05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 05-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=NifH1 {ECO:0000313|EMBL:ACN13985.1};
DE EC=1.18.6.1 {ECO:0000313|EMBL:ACN13985.1};
GN Name=nifH1 {ECO:0000313|EMBL:ACN13985.1};
GN OrderedLocusNames=HRM2_08720 {ECO:0000313|EMBL:ACN13985.1};
OS Desulforapulum autotrophicum (strain ATCC 43914 / DSM 3382 / VKM B-1955 /
OS HRM2) (Desulfobacterium autotrophicum).
OC Bacteria; Thermodesulfobacteriota; Desulfobacteria; Desulfobacterales;
OC Desulfobacteraceae; Desulforapulum.
OX NCBI_TaxID=177437 {ECO:0000313|EMBL:ACN13985.1, ECO:0000313|Proteomes:UP000000442};
RN [1] {ECO:0000313|EMBL:ACN13985.1, ECO:0000313|Proteomes:UP000000442}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43914 / DSM 3382 / HRM2
RC {ECO:0000313|Proteomes:UP000000442};
RX PubMed=19187283; DOI=10.1111/j.1462-2920.2008.01825.x;
RA Strittmatter A.W., Liesegang H., Rabus R., Decker I., Amann J., Andres S.,
RA Henne A., Fricke W.F., Martinez-Arias R., Bartels D., Goesmann A.,
RA Krause L., Puehler A., Klenk H.P., Richter M., Schuler M., Gloeckner F.O.,
RA Meyerdierks A., Gottschalk G., Amann R.;
RT "Genome sequence of Desulfobacterium autotrophicum HRM2, a marine sulfate
RT reducer oxidizing organic carbon completely to carbon dioxide.";
RL Environ. Microbiol. 11:1038-1055(2009).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the NifH/BchL/ChlL family.
CC {ECO:0000256|ARBA:ARBA00005504, ECO:0000256|RuleBase:RU003688}.
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DR EMBL; CP001087; ACN13985.1; -; Genomic_DNA.
DR RefSeq; WP_012663225.1; NC_012108.1.
DR AlphaFoldDB; C0QKB4; -.
DR STRING; 177437.HRM2_08720; -.
DR KEGG; dat:HRM2_08720; -.
DR eggNOG; COG1348; Bacteria.
DR eggNOG; COG2710; Bacteria.
DR HOGENOM; CLU_378090_0_0_7; -.
DR OrthoDB; 9778641at2; -.
DR Proteomes; UP000000442; Chromosome.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0018697; F:carbonyl sulfide nitrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016163; F:nitrogenase activity; IEA:UniProtKB-EC.
DR CDD; cd02040; NifH; 1.
DR Gene3D; 3.40.50.12380; Nitrogenase MoFe cofactor biosynthesis protein NifE, C-terminal; 1.
DR Gene3D; 3.40.50.1980; Nitrogenase molybdenum iron protein domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR000510; Nase/OxRdtase_comp1.
DR InterPro; IPR030655; NifH/chlL_CS.
DR InterPro; IPR000392; NifH/frxC.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR42864; LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE IRON-SULFUR ATP-BINDING PROTEIN; 1.
DR PANTHER; PTHR42864:SF2; LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE IRON-SULFUR ATP-BINDING PROTEIN; 1.
DR Pfam; PF00142; Fer4_NifH; 1.
DR Pfam; PF00148; Oxidored_nitro; 1.
DR PRINTS; PR00091; NITROGNASEII.
DR SUPFAM; SSF53807; Helical backbone' metal receptor; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00746; NIFH_FRXC_1; 1.
DR PROSITE; PS00692; NIFH_FRXC_2; 1.
DR PROSITE; PS51026; NIFH_FRXC_3; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|RuleBase:RU003688};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU003688};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|RuleBase:RU003688};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014, ECO:0000256|RuleBase:RU003688};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU003688};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003688};
KW Oxidoreductase {ECO:0000256|RuleBase:RU003688,
KW ECO:0000313|EMBL:ACN13985.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000442}.
FT DOMAIN 333..733
FT /note="Nitrogenase/oxidoreductase component 1"
FT /evidence="ECO:0000259|Pfam:PF00148"
SQ SEQUENCE 746 AA; 81002 MW; 31ABBE3AAB08BFD8 CRC64;
MKIAIYGKGG IGKSTISANL SAALAVSGKK VLQIGCDPKH DSTRLLLGGK RIVTALDYMK
ATPVALQRLD QVLHVGYGGI VCVEAGGPEP GVGCAGRGIL STFAMFDRLG LDMASFDVVL
YDVLGDVVCG GFAVPLRRGF ADRVYVVTSE EFMSIYAANN ILKGVKNFDE GGHRLAGLIL
NSRGRKEDRR PVESFARNVN LPVKQVVPRS ERFRRAEMLE KTLVEAFPDS LEAMIFHGLA
LDVLGNKTFY PARFLDEDSL DRLILHDKSP LSGDPGGDGE MPGGLDCPAL CRDDQCENLD
GAELPVKPFI SPGGKPTVFL SKRVLSREPL HGCAFSGALA TTTQIKDSVT VAHGPRSCTH
IAGQAILSVG FRLFNQRHIL LKNQVVPAVI SSDMDESMVI YGGRDRLIET LEQAMKQCPR
AVFLVTACPS GVIGDDPIAA VNEIRHRYPD VPVIPITSDG NLRGDYMQGV LNACMEGAGA
LVDKTVTPDP HCVNILAEKN IASNSESNFN TVAELLSGMG IHVNCRFVRN TSVAQLNHFL
KAPLNLVAYI DYFGRLMADF IEERLGVPTA SLPFPVGFTE SAAWVREIAA FFEKQAAGEK
LITGCHGHYR SMIKKYGPAL GGQRLMIITY VQNVDWIVEA AFDLGMEVVK VCLLGHCQGP
LFTTRYPGRF EVETDYNPAK RDKDVARLKP DLLLGNYTPG NLSLPVHVDM IPMCPDVGFY
GGIAFAHRWA TLIKAPIVEG WKTDGI
//
