ID C0QU11_PERMH Unreviewed; 688 AA.
AC C0QU11;
DT 05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 05-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Diguanylate cyclase/phosphodiesterase {ECO:0000313|EMBL:ACO03942.1};
GN OrderedLocusNames=PERMA_0385 {ECO:0000313|EMBL:ACO03942.1};
OS Persephonella marina (strain DSM 14350 / EX-H1).
OC Bacteria; Aquificota; Aquificae; Aquificales; Hydrogenothermaceae;
OC Persephonella.
OX NCBI_TaxID=123214 {ECO:0000313|EMBL:ACO03942.1, ECO:0000313|Proteomes:UP000001366};
RN [1] {ECO:0000313|EMBL:ACO03942.1, ECO:0000313|Proteomes:UP000001366}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14350 / EX-H1 {ECO:0000313|Proteomes:UP000001366};
RX PubMed=19136599; DOI=10.1128/JB.01645-08;
RA Reysenbach A.L., Hamamura N., Podar M., Griffiths E., Ferreira S.,
RA Hochstein R., Heidelberg J., Johnson J., Mead D., Pohorille A.,
RA Sarmiento M., Schweighofer K., Seshadri R., Voytek M.A.;
RT "Complete and draft genome sequences of six members of the Aquificales.";
RL J. Bacteriol. 191:1992-1993(2009).
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DR EMBL; CP001230; ACO03942.1; -; Genomic_DNA.
DR RefSeq; WP_012676181.1; NC_012440.1.
DR AlphaFoldDB; C0QU11; -.
DR STRING; 123214.PERMA_0385; -.
DR PaxDb; 123214-PERMA_0385; -.
DR KEGG; pmx:PERMA_0385; -.
DR eggNOG; COG2199; Bacteria.
DR eggNOG; COG2200; Bacteria.
DR HOGENOM; CLU_000445_70_46_0; -.
DR OrthoDB; 7057390at2; -.
DR Proteomes; UP000001366; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR InterPro; IPR045812; DAHL.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR PANTHER; PTHR33121:SF78; CYCLIC DI-GMP PHOSPHODIESTERASE PDEI-RELATED; 1.
DR Pfam; PF19443; DAHL; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001366};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 245..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 311..438
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 449..688
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
FT COILED 419..446
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 688 AA; 80468 MW; 8DDD93E63BA94986 CRC64;
MRKVYITILF AIVFSLSIVF FNNFTRRYVE KTAFTLSLIK DIESLEYQLN NEILKNSFML
YYNHDIIYEL IEDIYKKIEK LKNGYLTKDQ YSETYKYLLA FENAFKEKEE YIHDFETINS
IIKNTQTFIP SLVLRYIEIA QHENNEYFYL ISSIASSIYL AKNSLDEDFI DDLEEKIKKL
ESFRFKDPKL NEFNEVYLSH IRVFIENFTK YQYILDYILN KKKDIYFLSE TKKTFINSSK
EETKFITVFS TLLSIVFLVG LAIVAYLMIS LDRKNITLLK LKKNLEKALT TDELTGLPNR
LAFNIDKKIS KNPAFILINI DNFKQINDFY GTDTGDFVLV KVGEIISRFI KEKNIKGTVY
RIGADDFGIL VEDNTDNVEH ITKQLLTRIE KHRFKLADID LFINVSAGIS TERPLFEKAD
MALKRIKELK KKYLVYNEEL DLAKDIGNNL KILSIIKDAI ESERIFFVFQ PIKSVKDEKI
DKYEVLVRIK DREGNIIEPN VFIPIAKESG YYGYITRTVL EKTLKLIEEY PYRFSINLSI
EDIMDPDTRD FIYEKIITKR ELAERLTLEI LESESAGNYE DSHEFVKKVK MCGVQIAIDD
FGSGYSNFSH VLNLEPDYIK IDASLIKNID KDIYSQVVVS TIITFASKLG IKTIAEFVHN
DSIYEIVKDL GVDYVQGYYI GKPIDKLP
//
