ID C0R4Z5_WOLWR Unreviewed; 475 AA.
AC C0R4Z5;
DT 05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 05-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=WRi_013110 {ECO:0000313|EMBL:ACN95987.1};
OS Wolbachia sp. subsp. Drosophila simulans (strain wRi).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales;
OC Anaplasmataceae; Wolbachieae; Wolbachia.
OX NCBI_TaxID=66084 {ECO:0000313|EMBL:ACN95987.1, ECO:0000313|Proteomes:UP000001293};
RN [1] {ECO:0000313|EMBL:ACN95987.1, ECO:0000313|Proteomes:UP000001293}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=wRi {ECO:0000313|Proteomes:UP000001293};
RX PubMed=19307581; DOI=10.1073/pnas.0810753106;
RA Klasson L., Westberg J., Sapountzis P., Naeslund K., Lutnaes Y.,
RA Darby A.C., Veneti Z., Chen L., Braig H.R., Garrett R., Bourtzis K.,
RA Andersson S.G.;
RT "The mosaic genome structure of the Wolbachia wRi strain infecting
RT Drosophila simulans.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:5725-5730(2009).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP001391; ACN95987.1; -; Genomic_DNA.
DR RefSeq; WP_006280108.1; NZ_MKIF01000109.1.
DR AlphaFoldDB; C0R4Z5; -.
DR STRING; 66084.WRi_013110; -.
DR KEGG; wri:WRi_013110; -.
DR HOGENOM; CLU_040413_0_0_5; -.
DR Proteomes; UP000001293; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43711:SF1; HISTIDINE KINASE 1; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:ACN95987.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000313|EMBL:ACN95987.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 246..466
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 475 AA; 54540 MW; 6612EFDC3743BCFD CRC64;
MYKIGKLMFS ALGKNKYTKV IALFSSIFMI LFSVIYCNYL LRSNFLSSYR DSSVNLKSVL
ENGIIKKYHY LLIEKHHIKY KNFDYINQLV KLRAELLQSV SKVKDFSLIL YDQNGRIIFS
NFNTQDYDYE QLLTNDEIDK LLSDQEILYT TGNTLTSIFP IFHENSAKPS FFLKILRSYN
NSYVIAYGLF LIFLGLLLII LILIMFYLHF SNTKMLAKQH KTNIELQQIK EALEQENANK
LKFFASVTHE LRTPLNAIIG FAELIKNETL GSMDDSQYKE YADDIYNAGT HLLALINDVL
DFSKAESSSL TVEKVKFNLN KIIDSCVNML LPKLKEAGIN LKKEMTNKQL LVIADPKRMK
QVIINLLSNS IKFTPKDGLI RMVIKENIEK NLLTIEFHDN GIGIMQQDIY KVMSVFGQAD
SGYRNEGTGI GLPLSKKLVE LMGGTFDIKS EAKLGTTITL NFFYEEQTCE DSIDF
//
