ID C0WLC3_9CORY Unreviewed; 479 AA.
AC C0WLC3;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=NADH:ubiquinone reductase (non-electrogenic) {ECO:0000256|ARBA:ARBA00012637};
DE EC=1.6.5.9 {ECO:0000256|ARBA:ARBA00012637};
GN ORFNames=HMPREF0276_2259 {ECO:0000313|EMBL:EEI13655.1};
OS Corynebacterium accolens ATCC 49725.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=525260 {ECO:0000313|EMBL:EEI13655.1, ECO:0000313|Proteomes:UP000003641};
RN [1] {ECO:0000313|EMBL:EEI13655.1, ECO:0000313|Proteomes:UP000003641}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49725 {ECO:0000313|EMBL:EEI13655.1,
RC ECO:0000313|Proteomes:UP000003641};
RA Qin X., Bachman B., Battles P., Bell A., Bess C., Bickham C., Chaboub L.,
RA Chen D., Coyle M., Deiros D.R., Dinh H., Forbes L., Fowler G.,
RA Francisco L., Fu Q., Gubbala S., Hale W., Han Y., Hemphill L.,
RA Highlander S.K., Hirani K., Hogues M., Jackson L., Jakkamsetti A.,
RA Javaid M., Jiang H., Korchina V., Kovar C., Lara F., Lee S., Mata R.,
RA Mathew T., Moen C., Morales K., Munidasa M., Nazareth L., Ngo R.,
RA Nguyen L., Okwuonu G., Ongeri F., Patil S., Petrosino J., Pham C., Pham P.,
RA Pu L.-L., Puazo M., Raj R., Reid J., Rouhana J., Saada N., Shang Y.,
RA Simmons D., Thornton R., Warren J., Weissenberger G., Zhang J., Zhang L.,
RA Zhou C., Zhu D., Muzny D., Worley K., Gibbs R.;
RL Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a quinone + H(+) + NADH = a quinol + NAD(+);
CC Xref=Rhea:RHEA:46160, ChEBI:CHEBI:15378, ChEBI:CHEBI:24646,
CC ChEBI:CHEBI:57540, ChEBI:CHEBI:57945, ChEBI:CHEBI:132124; EC=1.6.5.9;
CC Evidence={ECO:0000256|ARBA:ARBA00000864};
CC -!- SIMILARITY: Belongs to the NADH dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00005272}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEI13655.1}.
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DR EMBL; ACGD01000045; EEI13655.1; -; Genomic_DNA.
DR AlphaFoldDB; C0WLC3; -.
DR eggNOG; COG1252; Bacteria.
DR HOGENOM; CLU_021377_7_1_11; -.
DR Proteomes; UP000003641; Unassembled WGS sequence.
DR GO; GO:0003954; F:NADH dehydrogenase activity; IEA:InterPro.
DR GO; GO:0006116; P:NADH oxidation; IEA:InterPro.
DR Gene3D; 3.50.50.100; -; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR045024; NDH-2.
DR PANTHER; PTHR43706:SF3; EXTERNAL NADH-UBIQUINONE OXIDOREDUCTASE 1, MITOCHONDRIAL-RELATED; 1.
DR PANTHER; PTHR43706; NADH DEHYDROGENASE; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 44..369
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
SQ SEQUENCE 479 AA; 52657 MW; 6CC50159CBAB0FB1 CRC64;
MGIKYARYVT SVYTIRVLKL SFLEEGRINS MTDTPYRPNG SRHHVVVVGG GFGGLNTVKK
LKNADVEITL IDKKNHHLFQ PMLYQVATGM ISAGEVAPST RQLLRNQDNV DFVNGNVTDI
NLEDQTVTAE LDDFSRTYSY DSLVVAAGSS QSYFGNDHFA EFAPGMKTLD DALELRSRII
SAFEKAELTD DPAERERLLT FIIVGAGPTG VELTGQIAEL ANRTLSDVYS TYGTSAAKIY
LLDGAPQVLP PFGKRLGRRA QRTLEKEGVN VRLNAMVTDV NEDSVTYKNM KTDEEVTLEG
ATKIWSAGVA ASPLGKMVAD QAGVEADRAG RVSVNDDMTV GDFNNVYIIG DMMSLNRLPG
LAQVAIQGGE HVAKLIETKV DEESTADEKE PFEYFDKGSM AIVTRFNAVV KLGKTEFSGF
PGWLAWLALH LTYVIGLRSR LAVLVNWAAN ILSRNRGNLE ITTQQRIARN LIDEAEEKN
//
