ID   C1BZL4_ESOLU            Unreviewed;       337 AA.
AC   C1BZL4;
DT   26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   26-MAY-2009, sequence version 1.
DT   03-MAY-2023, entry version 32.
DE   SubName: Full=DNAation factor subunit beta {ECO:0000313|EMBL:ACO14467.1};
GN   Name=DFFB {ECO:0000313|EMBL:ACO14467.1};
OS   Esox lucius (Northern pike).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC   Esocidae; Esox.
OX   NCBI_TaxID=8010 {ECO:0000313|EMBL:ACO14467.1};
RN   [1] {ECO:0000313|EMBL:ACO14467.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Head kidney {ECO:0000313|EMBL:ACO14467.1};
RX   PubMed=20433749; DOI=10.1186/1471-2164-11-279;
RA   Leong J.S., Jantzen S.G., von Schalburg K.R., Cooper G.A., Messmer A.M.,
RA   Liao N.Y., Munro S., Moore R., Holt R.A., Jones S.J., Davidson W.S.,
RA   Koop B.F.;
RT   "Salmo salar and Esox lucius full-length cDNA sequences reveal changes in
RT   evolutionary pressures on a post-tetraploidization genome.";
RL   BMC Genomics 11:279-279(2010).
RN   [2] {ECO:0000313|EMBL:ACO14467.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Head kidney {ECO:0000313|EMBL:ACO14467.1};
RG   cGRASP (B.F. Koop & W.S. Davidson);
RA   Leong J., Jantzen S., Cooper G., Davidson W.S., Koop B.F.;
RT   "Esox lucius ESTs and full-length cDNAs.";
RL   Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BT080043; ACO14467.1; -; mRNA.
DR   RefSeq; NP_001291002.1; NM_001304073.1.
DR   AlphaFoldDB; C1BZL4; -.
DR   GeneID; 105013682; -.
DR   KEGG; els:105013682; -.
DR   CTD; 1677; -.
DR   OrthoDB; 5399497at2759; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IEA:InterPro.
DR   GO; GO:0004520; F:DNA endonuclease activity; IEA:InterPro.
DR   GO; GO:0006309; P:apoptotic DNA fragmentation; IEA:InterPro.
DR   Gene3D; 3.10.20.10; -; 1.
DR   Gene3D; 6.10.140.170; -; 1.
DR   InterPro; IPR003508; CIDE-N_dom.
DR   InterPro; IPR039729; DFF40.
DR   InterPro; IPR015311; DFF40_C.
DR   InterPro; IPR044925; His-Me_finger_sf.
DR   PANTHER; PTHR13067; CASPASE-ACTIVATED DNASE; 1.
DR   PANTHER; PTHR13067:SF2; CASPASE-ACTIVATED DNASE; 1.
DR   Pfam; PF02017; CIDE-N; 1.
DR   Pfam; PF09230; DFF40; 1.
DR   SMART; SM00266; CAD; 1.
DR   SUPFAM; SSF54277; CAD & PB1 domains; 1.
DR   SUPFAM; SSF54060; His-Me finger endonucleases; 1.
DR   PROSITE; PS51135; CIDE_N; 1.
PE   2: Evidence at transcript level;
KW   Apoptosis {ECO:0000256|PROSITE-ProRule:PRU00447}.
FT   DOMAIN          7..83
FT                   /note="CIDE-N"
FT                   /evidence="ECO:0000259|PROSITE:PS51135"
SQ   SEQUENCE   337 AA;  39252 MW;  6D1A30370A729CC6 CRC64;
     MSGLSKKNKI VKIRSLNETK KYGMAATNLK ELLKKGCKLF QIPPFGSRIC LYEDGTELTE
     DYFQCLPDNA ELVLLAMDES WTGFVFDMSL LLNTGRNSGL IIDAAKGLLS EEQSPKRRKL
     LGDLLLHIED NSETENRSDD EDWFQGIDVR FKTKSAYMRY NCESRIRGYM KEVDSYAQTI
     QKPKLKDQYR KIVECFVMQL KSDKYNGCYF NRTEKEHERL CTKEGWFTCQ GAFDQDECKS
     LHSINPYGNR ESGILFSTWN LDHRIEKKRT VLPALVEALH NHKNSNINLD YFYNLLFTRE
     NLKLVHIVCH KKGAHDLLCD QKKIYQKGKR KVFLVCC
//