ID   C1CCM8_STRZJ            Unreviewed;       449 AA.
AC   C1CCM8;
DT   26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   26-MAY-2009, sequence version 1.
DT   27-MAR-2024, entry version 64.
DE   RecName: Full=Trk system potassium uptake protein TrkA {ECO:0000256|ARBA:ARBA00017378};
GN   OrderedLocusNames=SPJ_0451 {ECO:0000313|EMBL:ACO18620.1};
OS   Streptococcus pneumoniae (strain JJA).
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=488222 {ECO:0000313|EMBL:ACO18620.1, ECO:0000313|Proteomes:UP000002206};
RN   [1] {ECO:0000313|Proteomes:UP000002206}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JJA {ECO:0000313|Proteomes:UP000002206};
RX   PubMed=21034474; DOI=10.1186/gb-2010-11-10-r107;
RA   Donati C., Hiller N.L., Tettelin H., Muzzi A., Croucher N.J.,
RA   Angiuoli S.V., Oggioni M., Dunning Hotopp J.C., Hu F.Z., Riley D.R.,
RA   Covacci A., Mitchell T.J., Bentley S.D., Kilian M., Ehrlich G.D.,
RA   Rappuoli R., Moxon E.R., Masignani V.;
RT   "Structure and dynamics of the pan-genome of Streptococcus pneumoniae and
RT   closely related species.";
RL   Genome Biol. 11:R107.1-R107.19(2010).
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DR   EMBL; CP000919; ACO18620.1; -; Genomic_DNA.
DR   RefSeq; WP_000691685.1; NC_012466.1.
DR   AlphaFoldDB; C1CCM8; -.
DR   SMR; C1CCM8; -.
DR   KEGG; sjj:SPJ_0451; -.
DR   HOGENOM; CLU_046525_0_1_9; -.
DR   Proteomes; UP000002206; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 2.
DR   InterPro; IPR006036; K_uptake_TrkA.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR006037; RCK_C.
DR   InterPro; IPR036721; RCK_C_sf.
DR   InterPro; IPR003148; RCK_N.
DR   PANTHER; PTHR43833; POTASSIUM CHANNEL PROTEIN 2-RELATED-RELATED; 1.
DR   PANTHER; PTHR43833:SF5; TRK SYSTEM POTASSIUM UPTAKE PROTEIN TRKA; 1.
DR   Pfam; PF02080; TrkA_C; 2.
DR   Pfam; PF02254; TrkA_N; 2.
DR   PRINTS; PR00335; KUPTAKETRKA.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
DR   SUPFAM; SSF116726; TrkA C-terminal domain-like; 2.
DR   PROSITE; PS51202; RCK_C; 2.
DR   PROSITE; PS51201; RCK_N; 2.
PE   4: Predicted;
KW   NAD {ECO:0000256|ARBA:ARBA00023027}.
FT   DOMAIN          2..128
FT                   /note="RCK N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51201"
FT   DOMAIN          140..222
FT                   /note="RCK C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51202"
FT   DOMAIN          227..348
FT                   /note="RCK N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51201"
FT   DOMAIN          368..449
FT                   /note="RCK C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51202"
SQ   SEQUENCE   449 AA;  49774 MW;  BA7BF072DAD492BD CRC64;
     MKIILVGGGK VGFALCRSLV AEKHDVLLIE QDEAVLNHIV SRFDIIGILG NGADFAILEQ
     ASVQDCDIFI ALTEHDEVNM IAAVLAKKMG AKETIVRVRN PEYSNSYFKE KNILGFSLIV
     NPELLAARAI ANIIDFPNAL SVERFAGGRV SLMEFVVKST SGLCQMPISD FRKKFGNVIV
     CAIERDHQII IPSGDMTVQD KDRIFVTGNR VDMILFHNYF KSRAVKSLLI VGAGRIAYYL
     LGILKDSRID TKVIEINPEI ASFFSEKFPN LYIVQGDGTA KDILLEESAQ HYDAVATLTG
     VDEENLITSM FLDRVGVQKN ITKVNRTSLL EIINAPDFSS IITPKSIAVD TIMHFIRGRV
     NAQYSDLQAM HHLANGQIET LQFHIKEANK MTAKPLSQLK LKKGVLIAAI IRKGKTIFPT
     GEDMLEVGDK LLVTTLLPNI TKIYDLIAR
//