ID C1G9V0_PARBD Unreviewed; 840 AA.
AC C1G9V0;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 2.
DT 27-MAR-2024, entry version 72.
DE RecName: Full=STAS domain-containing protein {ECO:0000259|PROSITE:PS50801};
GN ORFNames=PADG_04036 {ECO:0000313|EMBL:EEH47952.2};
OS Paracoccidioides brasiliensis (strain Pb18).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX NCBI_TaxID=502780 {ECO:0000313|EMBL:EEH47952.2, ECO:0000313|Proteomes:UP000001628};
RN [1] {ECO:0000313|EMBL:EEH47952.2, ECO:0000313|Proteomes:UP000001628}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pb18 {ECO:0000313|EMBL:EEH47952.2,
RC ECO:0000313|Proteomes:UP000001628};
RX PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT "Comparative genomic analysis of human fungal pathogens causing
RT paracoccidioidomycosis.";
RL PLoS Genet. 7:E1002345-E1002345(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU362052}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362052}.
CC -!- SIMILARITY: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
CC {ECO:0000256|ARBA:ARBA00008692, ECO:0000256|RuleBase:RU362052}.
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DR EMBL; KN275960; EEH47952.2; -; Genomic_DNA.
DR RefSeq; XP_010759289.1; XM_010760987.1.
DR AlphaFoldDB; C1G9V0; -.
DR STRING; 502780.C1G9V0; -.
DR GeneID; 22583237; -.
DR KEGG; pbn:PADG_04036; -.
DR VEuPathDB; FungiDB:PADG_04036; -.
DR eggNOG; KOG0236; Eukaryota.
DR HOGENOM; CLU_003182_8_1_1; -.
DR InParanoid; C1G9V0; -.
DR OMA; TRGESMF; -.
DR OrthoDB; 1082533at2759; -.
DR Proteomes; UP000001628; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008509; F:monoatomic anion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0008271; F:secondary active sulfate transmembrane transporter activity; IEA:InterPro.
DR CDD; cd07042; STAS_SulP_like_sulfate_transporter; 1.
DR Gene3D; 3.30.750.24; STAS domain; 1.
DR InterPro; IPR018045; S04_transporter_CS.
DR InterPro; IPR011547; SLC26A/SulP_dom.
DR InterPro; IPR001902; SLC26A/SulP_fam.
DR InterPro; IPR002645; STAS_dom.
DR InterPro; IPR036513; STAS_dom_sf.
DR NCBIfam; TIGR00815; sulP; 1.
DR PANTHER; PTHR11814:SF55; SODIUM-INDEPENDENT SULFATE ANION TRANSPORTER; 1.
DR PANTHER; PTHR11814; SULFATE TRANSPORTER; 1.
DR Pfam; PF00916; Sulfate_transp; 1.
DR PROSITE; PS01130; SLC26A; 1.
DR PROSITE; PS50801; STAS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362052};
KW Reference proteome {ECO:0000313|Proteomes:UP000001628};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362052};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362052}; Transport {ECO:0000256|RuleBase:RU362052}.
FT TRANSMEM 91..111
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 123..139
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 144..161
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 173..194
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 201..220
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 256..274
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 286..309
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 381..400
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 412..431
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 467..487
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT DOMAIN 578..703
FT /note="STAS"
FT /evidence="ECO:0000259|PROSITE:PS50801"
FT REGION 725..750
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 732..750
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 840 AA; 91618 MW; 83F901E6463025E3 CRC64;
MATPNGKMTT KVGTLLAKGL GIKKGNQDPF GSDPAYGVSS VSLGSAGPYV EVEPDSGGWV
RELVPGRHQV LPYFLNLFPF LRWITRYNLQ WFIGDLVAGI TVGAVVVPQG MAYAKLAELE
PEFGLYSSFM GVLIYWFFAT SKDITIGPVA VMSTLVGHVV IKVKKAHPEI PGHVIASALA
VICGGIVTFI GLIRCGWIVD FIPLTAITAF MTGSAISIAA GQVPSMMGMS GFNTRDTTYK
VIINTLKHLP DTKIDAAMGL TALFLLYLIR WACSYGAKRN PSRKKLFFFL ATLRTVVVIL
LYVMVSWLVN RHHRKKPTFK ILGNVPRGFQ HAAVPQVDAK IVKAFAGDIP AAVIVLLIEH
IAISKSFGRI NNYTIDPSQE LVAIGVTNLL GPFLGGYPAT GSFSRTAIKS KAGVRTPFAG
VITAILVLLS IYALPAVFFY IPNASLSAVI IHAVGDLITP PNVVYQFWRV SPLEVVVFFV
GVIVTIFSTI ENGIYFTVCV SLAILLFRVV KAQGRFLGRV KVHSVVGNQT SPSGGKYDGL
GSSDGALTST NPSFRNIFLP LNHLDGSNPE IEIEQPSPGI FIYQFSEGFN YPNANHYLDY
LVTTIYKHTR RTNLDSYPSV GDRPWCDPGP RKGQVEEDRS HLPTLKAIIL DFSSVNNVDV
TSTQNLIDVR NQLDKYAAPQ PVHWHFAHVN NRWTKRALVS AGFGYPTPSP GGNIRWKPIF
SVAELGSNHT GDPDASPEQR NNSWQPTSGK QFDIEAVEPA PVEKSPIKIT AKDVENGSSG
SEHEVRTDWD RRQGYIAESR RIAVVHSLNR PFFHLDLTSA LQSALANAEA SAVATKLPDS
//
