ID   C1GA36_PARBD            Unreviewed;       498 AA.
AC   C1GA36;
DT   26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   26-MAY-2009, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   RecName: Full=PLD phosphodiesterase domain-containing protein {ECO:0000259|PROSITE:PS50035};
GN   ORFNames=PADG_04122 {ECO:0000313|EMBL:EEH48038.1};
OS   Paracoccidioides brasiliensis (strain Pb18).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX   NCBI_TaxID=502780 {ECO:0000313|EMBL:EEH48038.1, ECO:0000313|Proteomes:UP000001628};
RN   [1] {ECO:0000313|EMBL:EEH48038.1, ECO:0000313|Proteomes:UP000001628}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pb18 {ECO:0000313|EMBL:EEH48038.1,
RC   ECO:0000313|Proteomes:UP000001628};
RX   PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA   Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA   Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA   Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA   Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA   Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA   Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA   Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA   Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT   "Comparative genomic analysis of human fungal pathogens causing
RT   paracoccidioidomycosis.";
RL   PLoS Genet. 7:E1002345-E1002345(2011).
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DR   EMBL; KN275960; EEH48038.1; -; Genomic_DNA.
DR   RefSeq; XP_010759732.1; XM_010761430.1.
DR   AlphaFoldDB; C1GA36; -.
DR   GeneID; 22583311; -.
DR   KEGG; pbn:PADG_04122; -.
DR   VEuPathDB; FungiDB:PADG_04122; -.
DR   eggNOG; ENOG502RYWJ; Eukaryota.
DR   HOGENOM; CLU_030268_0_0_1; -.
DR   InParanoid; C1GA36; -.
DR   OMA; MDRASWY; -.
DR   OrthoDB; 2123597at2759; -.
DR   Proteomes; UP000001628; Unassembled WGS sequence.
DR   GO; GO:0030572; F:phosphatidyltransferase activity; IEA:UniProt.
DR   GO; GO:0032049; P:cardiolipin biosynthetic process; IEA:UniProt.
DR   CDD; cd00138; PLDc_SF; 1.
DR   Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR   InterPro; IPR025202; PLD-like_dom.
DR   InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR   PANTHER; PTHR21248; CARDIOLIPIN SYNTHASE; 1.
DR   PANTHER; PTHR21248:SF11; PLD PHOSPHODIESTERASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF13091; PLDc_2; 1.
DR   SMART; SM00155; PLDc; 2.
DR   SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR   PROSITE; PS50035; PLD; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001628};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          168..195
FT                   /note="PLD phosphodiesterase"
FT                   /evidence="ECO:0000259|PROSITE:PS50035"
FT   DOMAIN          420..447
FT                   /note="PLD phosphodiesterase"
FT                   /evidence="ECO:0000259|PROSITE:PS50035"
SQ   SEQUENCE   498 AA;  56016 MW;  2DC342ACCF8DA977 CRC64;
     MAITQHSIGK WREHIATDPL EAHQHSSLAD SATAASLEPS FCTGTGDSLL SNYILPDLET
     ADQEVIFVTC FWAAKSKSRQ HFFKTLQRLS AKVIRKRRAS TNPITTPVEN IKVYLCFSSV
     SILQKLKHTK SENGYIYEPS EWNQKLGLPK PSQIPGVDLT VKSIFIRPFS VMHPKFAIVD
     RKFVWVPSCN VSWESWFEGA FRLRGSIVEK FYTWWAQVWA PVITPESPQT IGLQDTADRA
     TTSGILPPMI LPRQESPLRL IKSFPNISSS QDVTTLFLPS SHHQDPQFRP CPFQCAVPEP
     RTPLNAFTSF LFASAKKEIY IITPNITARP VVNGLLKALE RGVDVTIVTN TNLMVLEQLV
     TAGTTTKRCM KDLIRQHKKL LKSGARDEEE GGQETNTRGE LRIRYWEARN MGRDVNGESA
     FRRTHLKLTI VDRAVVIFGS GNMDRASWYT SQEVGVAMYS TDVAKKILDG DGPLTDVERC
     TRYCYQSFEA GERDPGAV
//