ID C1GLJ8_PARBD Unreviewed; 671 AA.
AC C1GLJ8;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 2.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=CBS domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PADG_08239 {ECO:0000313|EMBL:EEH43314.2};
OS Paracoccidioides brasiliensis (strain Pb18).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX NCBI_TaxID=502780 {ECO:0000313|EMBL:EEH43314.2, ECO:0000313|Proteomes:UP000001628};
RN [1] {ECO:0000313|EMBL:EEH43314.2, ECO:0000313|Proteomes:UP000001628}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pb18 {ECO:0000313|EMBL:EEH43314.2,
RC ECO:0000313|Proteomes:UP000001628};
RX PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT "Comparative genomic analysis of human fungal pathogens causing
RT paracoccidioidomycosis.";
RL PLoS Genet. 7:E1002345-E1002345(2011).
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DR EMBL; KN275971; EEH43314.2; -; Genomic_DNA.
DR RefSeq; XP_010763495.1; XM_010765193.1.
DR AlphaFoldDB; C1GLJ8; -.
DR STRING; 502780.C1GLJ8; -.
DR GeneID; 22586569; -.
DR KEGG; pbn:PADG_08239; -.
DR VEuPathDB; FungiDB:PADG_08239; -.
DR eggNOG; ENOG502QVK2; Eukaryota.
DR HOGENOM; CLU_009026_1_0_1; -.
DR InParanoid; C1GLJ8; -.
DR OMA; RERKQFF; -.
DR OrthoDB; 1328303at2759; -.
DR Proteomes; UP000001628; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd17781; CBS_pair_MUG70_1; 1.
DR CDD; cd17782; CBS_pair_MUG70_2; 1.
DR CDD; cd06409; PB1_MUG70; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 2.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR000270; PB1_dom.
DR PANTHER; PTHR48108:SF6; CBS DOMAIN-CONTAINING PROTEIN CBSX1, CHLOROPLASTIC; 1.
DR PANTHER; PTHR48108; CBS DOMAIN-CONTAINING PROTEIN CBSX2, CHLOROPLASTIC; 1.
DR Pfam; PF00571; CBS; 4.
DR Pfam; PF00564; PB1; 1.
DR SMART; SM00116; CBS; 4.
DR SMART; SM00666; PB1; 1.
DR SUPFAM; SSF54277; CAD & PB1 domains; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 2.
DR PROSITE; PS51371; CBS; 4.
DR PROSITE; PS51745; PB1; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001628};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 646..665
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 97..158
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 164..220
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 267..324
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 333..390
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 474..575
FT /note="PB1"
FT /evidence="ECO:0000259|PROSITE:PS51745"
FT REGION 1..94
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 434..460
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 577..624
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 36..55
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 56..77
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 579..593
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 671 AA; 72600 MW; 50818BB649540510 CRC64;
MSAAGQGTFR NRTVGRGQIP FDGSPSGIPR KVETPPVPQS ATSDVGSSSA LSTSRQKQTK
RDEAIRKKME ADLNKKRHNP TRARHTRKAP PGTVMALKPS HALQIKPNTT VAEAAQLMAA
KREDCVLVTD EDERIAGIFT AKDLAFRVVG AGIRARDVTI AEIMTKNPLC ARTDTSATDA
LDLMVRKGFR HLPVMDENQD ISGILDITKC FYDAMEKLER AYSSSRKLYD ALEGVQSELG
SNQPQQIIQY VEALRQKMSG PTLETVLNGL PPTTVSVRTS VREAAALMKE NHTTALLVQD
QGSITGIFTS KDIVLRVIAP GLDPNTCSVV RVMTPHPDFA PTDMSIQAAL RKMHDGHYLN
LPVMNEAGEI VGMVDVLKLT YATLEQVNTM SSNESEGPAW NKFWLSMDHE SDSIISGSHG
GHQVSTPIRS VVSPELSRTH VERENSVLPN DSASHHGDDA ASDVLEPRVA HNEDTPFPFK
FKAPSGRVHR LHVTPSAGVS DLVSQVSLKL GPEVEAVGGY ALVEDGKLSN SGYALSYVDN
EGDTVSITTD QDLWDAVTLS RSSNMDKVDL YVHDPEKQPV IATPPPPPVA QQVPSVSLKP
ATPPGAIEEE EEQSNVGNRS SVTDRSQTIV RFPTAEQLIN GVPNELILPG AIVTLAVAIV
GVFVLSRIGN R
//
