ID   C1GWP2_PARBA            Unreviewed;       917 AA.
AC   C1GWP2;
DT   26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   26-MAY-2009, sequence version 1.
DT   27-MAR-2024, entry version 74.
DE   SubName: Full=Mitochondrial dynamin GTPase (Msp1) {ECO:0000313|EMBL:EEH40961.1};
GN   ORFNames=PAAG_02937 {ECO:0000313|EMBL:EEH40961.1};
OS   Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides
OS   brasiliensis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX   NCBI_TaxID=502779 {ECO:0000313|EMBL:EEH40961.1, ECO:0000313|Proteomes:UP000002059};
RN   [1] {ECO:0000313|EMBL:EEH40961.1, ECO:0000313|Proteomes:UP000002059}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-826 / Pb01 {ECO:0000313|Proteomes:UP000002059};
RX   PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA   Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA   Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA   Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA   Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA   Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA   Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA   Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA   Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT   "Comparative genomic analysis of human fungal pathogens causing
RT   paracoccidioidomycosis.";
RL   PLoS Genet. 7:E1002345-E1002345(2011).
CC   -!- SIMILARITY: Belongs to the TRAFAC class dynamin-like GTPase
CC       superfamily. Dynamin/Fzo/YdjA family. {ECO:0000256|RuleBase:RU003932}.
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DR   EMBL; KN293997; EEH40961.1; -; Genomic_DNA.
DR   RefSeq; XP_002795461.1; XM_002795415.2.
DR   AlphaFoldDB; C1GWP2; -.
DR   STRING; 502779.C1GWP2; -.
DR   GeneID; 9098679; -.
DR   KEGG; pbl:PAAG_02937; -.
DR   VEuPathDB; FungiDB:PAAG_02937; -.
DR   eggNOG; KOG0446; Eukaryota.
DR   HOGENOM; CLU_008640_0_0_1; -.
DR   OMA; PLKMGYV; -.
DR   OrthoDB; 1052588at2759; -.
DR   Proteomes; UP000002059; Partially assembled WGS sequence.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0006996; P:organelle organization; IEA:UniProt.
DR   CDD; cd08771; DLP_1; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR022812; Dynamin.
DR   InterPro; IPR001401; Dynamin_GTPase.
DR   InterPro; IPR019762; Dynamin_GTPase_CS.
DR   InterPro; IPR045063; Dynamin_N.
DR   InterPro; IPR000375; Dynamin_stalk.
DR   InterPro; IPR030381; G_DYNAMIN_dom.
DR   InterPro; IPR020850; GED_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR11566; DYNAMIN; 1.
DR   PANTHER; PTHR11566:SF237; INTERFERON-INDUCED GTP-BINDING PROTEIN MX; 1.
DR   Pfam; PF01031; Dynamin_M; 1.
DR   Pfam; PF00350; Dynamin_N; 1.
DR   PRINTS; PR00195; DYNAMIN.
DR   SMART; SM00053; DYNc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS00410; G_DYNAMIN_1; 1.
DR   PROSITE; PS51718; G_DYNAMIN_2; 1.
DR   PROSITE; PS51388; GED; 1.
PE   3: Inferred from homology;
KW   GTP-binding {ECO:0000256|RuleBase:RU003932};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU003932};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002059}.
FT   DOMAIN          237..510
FT                   /note="Dynamin-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51718"
FT   DOMAIN          802..895
FT                   /note="GED"
FT                   /evidence="ECO:0000259|PROSITE:PS51388"
FT   REGION          161..183
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   917 AA;  100947 MW;  FD9E269535A56B38 CRC64;
     MSGRLFSHGA AVLARRSLLA RQLHNIGTRT GSLLRSQGAV GLRGMLWQLR ANWIHNVPVA
     RTISFARVLP KLALKFARIP AMFGGAMVAG LAYIQYQAAQ AGNYALDIVK QAGETASGVA
     LGVFRNIQDV AEQTNRGWQR TKAGVELPEW AQKILRLNEQ AESGGGGSSE GGGGSPKQSK
     AGAAAVAGAA AGAALDHDSD DSLATERKNA IDDQMMILTR KMIEIRNMLQ RVGQSNALTL
     PSIVVIGSQS SGKSSVLEAI VGHEFLPKGS NMVTRRPIEL TLVNTPNSQE EYGEFPALGL
     GKITDFSQIQ RTLTDLNLAV SEKDCISDDP IQLSISSPHI PDLSLIDLPG YIQVAGRDQP
     PELKQKISDL CDKYIQAPNI ILAISAADVD LANSTALRAS RRVDPRGERT IGVITKMDLV
     DPERGASILA DRKYPLRLGY VGVVSRIPHT AGLFSRGNGN ITNAIIKNES AFFNSHPKEF
     GSESELSVGT TTLRKKLMHT LEQSMAASLA GTRDAIIQEL EEATYEFKVQ YNDRPLSAES
     YLAESLDSFK HSFKEFSENF GRPQVRELLK NELDQRVLDI LAQRYWNKPV DDLSPPVPEP
     DPLSDLPRAD PESLYWHRKL DASSSALTKL GIGRLATTTV ANALQNHVDD LIASSTFAAH
     PYAQKEIADA TATILNDRFF STSDQVENCI KPYKFEIEVD DLEWAKGREN IGNVLKEELK
     ACGYALKHVE DDIGKRKLKD VMGFIDKVRK GDATIEGDGS GGAGGFSAAL LQKGREAVFL
     RDRADLLKMR LLAIRSKQCS TKRNKYYCPE VFLDVVADKL TATAVLFLNV ELLSEFYYNF
     PRELDLRLGR HLSASEIERF AREDPRIRRH LDVIQKKEML ELVLEKIESL RQLEGRSKAA
     VHQMGPGKER SKGWRLF
//