ID C1GZ35_PARBA Unreviewed; 369 AA.
AC C1GZ35;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 2.
DT 03-MAY-2023, entry version 61.
DE SubName: Full=Glycerophosphoryl diester phosphodiesterase family protein {ECO:0000313|EMBL:EEH41858.2};
GN ORFNames=PAAG_03779 {ECO:0000313|EMBL:EEH41858.2};
OS Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides
OS brasiliensis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX NCBI_TaxID=502779 {ECO:0000313|EMBL:EEH41858.2, ECO:0000313|Proteomes:UP000002059};
RN [1] {ECO:0000313|EMBL:EEH41858.2, ECO:0000313|Proteomes:UP000002059}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-826 / Pb01 {ECO:0000313|Proteomes:UP000002059};
RX PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT "Comparative genomic analysis of human fungal pathogens causing
RT paracoccidioidomycosis.";
RL PLoS Genet. 7:E1002345-E1002345(2011).
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DR EMBL; KN294000; EEH41858.2; -; Genomic_DNA.
DR RefSeq; XP_015702151.1; XM_015845062.1.
DR AlphaFoldDB; C1GZ35; -.
DR STRING; 502779.C1GZ35; -.
DR GeneID; 9097443; -.
DR KEGG; pbl:PAAG_03779; -.
DR VEuPathDB; FungiDB:PAAG_03779; -.
DR HOGENOM; CLU_030006_1_2_1; -.
DR OMA; HLPYCRR; -.
DR OrthoDB; 5475129at2759; -.
DR Proteomes; UP000002059; Partially assembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd08570; GDPD_YPL206cp_fungi; 1.
DR Gene3D; 3.20.20.190; Phosphatidylinositol (PI) phosphodiesterase; 1.
DR InterPro; IPR030395; GP_PDE_dom.
DR InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR PANTHER; PTHR43805; GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE; 1.
DR PANTHER; PTHR43805:SF1; GP-PDE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF03009; GDPD; 1.
DR SUPFAM; SSF51695; PLC-like phosphodiesterases; 1.
DR PROSITE; PS51704; GP_PDE; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002059};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 328..347
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 57..297
FT /note="GP-PDE"
FT /evidence="ECO:0000259|PROSITE:PS51704"
FT REGION 28..49
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 369 AA; 41797 MW; C66010D9E36DCAED CRC64;
MSTETAIFED VTATLDYSVG DCISTTHPAQ PLEPRSHFPK SSWANPGYNK DGTRGVPLTV
AHRGFKAKYP ENTMCAFSHA VKVGAQGLEA DMHISKDGVV VISHDATLQR CYGVRKRIID
CDWEYLSTLR TIKPPFEPMP RLLYLLQYIS VPERSHVWLL LDIKLDNDPE AIMRAIAKTV
LSIPSVHRPW NERIILGCWA AKYFPLCHTY LPKYPVALIT YSLLYARKFL KVPNISFSIE
LKALMGPGGA KFLADVKHSR RQIFVWTVNE ESLMRWSVRN EVDGVITDDP ELLRKISDGC
EGDRLHYGGY ISNFHDSGDD GITVLQRVNV LVAAVILFVL GGVFAIVHPA DLKEFTEEPY
EEYDRWEEL
//
