ID C1H1J6_PARBA Unreviewed; 1810 AA.
AC C1H1J6;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 24-JAN-2024, entry version 66.
DE RecName: Full=U3 small nucleolar RNA-associated protein 10 {ECO:0000256|ARBA:ARBA00015399, ECO:0000256|RuleBase:RU367065};
GN ORFNames=PAAG_04640 {ECO:0000313|EMBL:EEH33590.1};
OS Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides
OS brasiliensis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX NCBI_TaxID=502779 {ECO:0000313|EMBL:EEH33590.1, ECO:0000313|Proteomes:UP000002059};
RN [1] {ECO:0000313|EMBL:EEH33590.1, ECO:0000313|Proteomes:UP000002059}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-826 / Pb01 {ECO:0000313|Proteomes:UP000002059};
RX PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT "Comparative genomic analysis of human fungal pathogens causing
RT paracoccidioidomycosis.";
RL PLoS Genet. 7:E1002345-E1002345(2011).
CC -!- FUNCTION: Involved in nucleolar processing of pre-18S ribosomal RNA.
CC Involved in ribosome biosynthesis. {ECO:0000256|ARBA:ARBA00025076}.
CC -!- SUBUNIT: Component of the ribosomal small subunit (SSU) processome.
CC {ECO:0000256|ARBA:ARBA00011399, ECO:0000256|RuleBase:RU367065}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604, ECO:0000256|RuleBase:RU367065}.
CC -!- SIMILARITY: Belongs to the HEATR1/UTP10 family.
CC {ECO:0000256|ARBA:ARBA00010559, ECO:0000256|RuleBase:RU367065}.
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DR EMBL; KN294002; EEH33590.1; -; Genomic_DNA.
DR RefSeq; XP_002793730.1; XM_002793684.2.
DR AlphaFoldDB; C1H1J6; -.
DR STRING; 502779.C1H1J6; -.
DR GeneID; 9096877; -.
DR KEGG; pbl:PAAG_04640; -.
DR VEuPathDB; FungiDB:PAAG_04640; -.
DR eggNOG; KOG1837; Eukaryota.
DR HOGENOM; CLU_001128_3_1_1; -.
DR OMA; NDVMWKQ; -.
DR OrthoDB; 5480100at2759; -.
DR Proteomes; UP000002059; Partially assembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-UniRule.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 3.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR012954; BP28_C_dom.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR022125; U3snoRNP10_N.
DR InterPro; IPR040191; UTP10.
DR PANTHER; PTHR13457; BAP28; 1.
DR PANTHER; PTHR13457:SF1; HEAT REPEAT-CONTAINING PROTEIN 1; 1.
DR Pfam; PF08146; BP28CT; 1.
DR Pfam; PF12397; U3snoRNP10; 1.
DR SMART; SM01036; BP28CT; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR PROSITE; PS50077; HEAT_REPEAT; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU367065};
KW Reference proteome {ECO:0000313|Proteomes:UP000002059};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW ECO:0000256|RuleBase:RU367065};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517,
KW ECO:0000256|RuleBase:RU367065};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552,
KW ECO:0000256|RuleBase:RU367065}.
FT DOMAIN 1513..1666
FT /note="BP28 C-terminal"
FT /evidence="ECO:0000259|SMART:SM01036"
FT REPEAT 1771..1809
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
SQ SEQUENCE 1810 AA; 201127 MW; 53CBD8421784A889 CRC64;
MASSLTAQLS QIAATSTHQL DLKAQRVAHS KSLIFEQRDA VSQSFDTLYQ ICYEGFQELC
ALDSRFSKFR RTIFSEQSKT EDRLDMNAEQ NKELDTVLEE FLALVGSRLL LQPAVKAVEW
LVRRFRVHEH NISFLLLTFL PYHTMELFKA LLSILPENLP PTFKILNPYR RSLTLPPRHA
IVHSASTNNS FLAALNHYVL QVSKSRAHYQ GLLAFWAGVA TEAVANMLDS TSSGRRQVER
RNQEDVLLQI LPVLHSGFCL SKVPELVIGC YMICIVIANK ASLEDNVLDG LMEAIVGTWS
QETRLAAMTC LSVLVQHKNS PGLPRSVVKS ITRFENSLDL IVDLHTRYSI TGLLLGLIDG
CVQEIHNQKD LSPLMFIDTA IQRDILESED LAKVMVLILR AAADLQASSR MAEESRTILS
RMIQHFTESE SLAPILQNAI GESNIDINAL EMALETALGN IAAPMAIEDV EMEDVADAVE
KEDAFAKALE DISQSTEEVS FLAGVSSSTY DQLAYAFILA AGSKEKVLKF TDLPILRRDA
SLQSPLYLSF FIRFFSGPYP PVSRTAAIEI VTAYLSESVS KSFNMQAILP YIVSSLCDPS
ERVRRGTASL LASFERTCAK VKNEDESKPQ SSWGFGDIYG KTERSKSLRW ISPRSVYKAT
HRALLPALEE YVLDPTQIGS LLKSAIRGTS STTDTSDSEL KKSVRQELFT FLCSHAILTP
LYAVKIRLLK ILNHIGKIGS ATRTEELSPI LDQWRLLDDD SVANIAKIEQ VNIPELEGQI
LEIVSAKHKN SVDILVSSVT SQPCAPRTDF VKAVFTRLSQ IWPSLKEDSR TNAADTFLEM
ALGPSTVDGE LPNACRDLLL TVDLSGHILS RFLNKISAYI VDTEPQGSAA KRRRTSQNNM
VAMNTRDPKE LSQMIGQVTF ILELIDGSSP ENHPQLLGGL FQTLAALHHL KLKLQAEMGY
LLSLVLGIML AIINKAKLSP KLKFDTSVIR PDLIIDCVRT SQSPQVQNSA LLLVAGLATI
APELILHSVM PIFTFMGSNV LKKDDQYSAL VIDQTIDQVV PPLIQSLHNQ KRDVVSGTSE
LLLSFTAAFE HIPSHRRLRL FEALITKLGA EDFLFAVFAM LANRYGTDRD VLGMMTSLVG
NLGVERQLLS YTKYLSLVQD ALLPKPNLSH TLLGVGGEDG KDPSRIAANL LQTLSHLLQS
ASLRSQMNKA FDSDDAAVAP IHNLFSRILE QLLALADTVR GNKPVSKACG DALGSLLGAL
SLVDFLDTIE VLLRRPNDDL RRRVLRLLEN RLEQSHDRDS ASQSRVLVFL STLVGILEES
PDVLLKHAAV VCIDRVAEKY GKKDPDFVVG AARVVAGESC IGQADDRIRV IGMLCLASIT
EVLGEAIIPV LPEIFSRSFG LLKATLRSSR KYLQLHDAIY SLISALLSHI PWMISDYHLN
NILQLSFMSA AADLPEECND NRREALRLLA RHVDVNETFK AVEFNWSFAL SEGPKAVGEL
LEVTNLCIEK HPKSSTIKNV PVLAKLLEKA LDIRRTQFSL SDTSRYGADD VNDIESQVND
MAIKMIYKLN DTIFRPLFVQ LTEWATKGIR ESDSTGRLLR LTTFFKFLGS FFGTLKSIVT
SYSSYIIEST VEILNTARCN DKESKGLWLA TMQMLRSSFE HDQDEFWQSP THLAAISTPL
VTQLSRSTNP PTLKLITAEA IPTIVELASA ADSPENHKEL NTAIMKFMRP GMSSDGRNGG
DNPYTRLAAV RCEFSLTERL GEEWLALLPE MLPYISELME DDDENVEKEV RRWVLAIEEV
LGEKLDDMLV
//
