ID C1JFH2_9LAMI Unreviewed; 251 AA.
AC C1JFH2;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=chalcone synthase {ECO:0000256|ARBA:ARBA00012975};
DE EC=2.3.1.74 {ECO:0000256|ARBA:ARBA00012975};
DE Flags: Fragment;
GN Name=CHS-A {ECO:0000313|EMBL:ACO56384.1};
OS Rhabdothamnus solandri.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Lamiales; Gesneriaceae; Gesnerioideae; Coronanthereae;
OC Coronantherinae; Rhabdothamnus.
OX NCBI_TaxID=243673 {ECO:0000313|EMBL:ACO56384.1};
RN [1] {ECO:0000313|EMBL:ACO56384.1}
RP NUCLEOTIDE SEQUENCE.
RA Kotarski M.A., Caro S.E., Sweeney C.S., Greene M.J., Stampfle J.M.,
RA Leonard D.A.;
RT "Placement of four problematic genera of Gesneriaceae using the duplicated
RT chalcone synthase (CHS) nuclear gene.";
RL Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: The primary product of this enzyme is 4,2',4',6'-
CC tetrahydroxychalcone (also termed naringenin-chalcone or chalcone)
CC which can under specific conditions spontaneously isomerize into
CC naringenin. {ECO:0000256|ARBA:ARBA00002969}.
CC -!- PATHWAY: Secondary metabolite biosynthesis; flavonoid biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004966}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|ARBA:ARBA00005531,
CC ECO:0000256|RuleBase:RU003633}.
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DR EMBL; FJ603630; ACO56384.1; -; Genomic_DNA.
DR AlphaFoldDB; C1JFH2; -.
DR UniPathway; UPA00154; -.
DR GO; GO:0102128; F:chalcone synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0016210; F:naringenin-chalcone synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0009813; P:flavonoid biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd00831; CHS_like; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR InterPro; IPR018088; Chalcone/stilbene_synthase_AS.
DR InterPro; IPR011141; Polyketide_synthase_type-III.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11877:SF14; CHALCONE SYNTHASE; 1.
DR PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR Pfam; PF02797; Chal_sti_synt_C; 1.
DR Pfam; PF00195; Chal_sti_synt_N; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00441; CHALCONE_SYNTH; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000256|RuleBase:RU003633};
KW Flavonoid biosynthesis {ECO:0000256|ARBA:ARBA00023241};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003633}.
FT DOMAIN 1..122
FT /note="Chalcone/stilbene synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00195"
FT DOMAIN 132..250
FT /note="Chalcone/stilbene synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02797"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ACO56384.1"
FT NON_TER 251
FT /evidence="ECO:0000313|EMBL:ACO56384.1"
SQ SEQUENCE 251 AA; 27317 MW; BB02D9F2E6416B82 CRC64;
KEAAQKAIKE WGQPKSKITH LIFCTTSGVD MPGVDFQVTK LLGLSPSVKR FMMYQQGCYA
GGTVIRMAKD LAENNAGARV LVICSEITAL TFHGPSDTHL DILVGQALFG DGAAAMIVGS
NPVVGVEWPL FQLVSTAQTN LPDSDTAIDG HLREVGLIFH ISKDVPSLIS KNIEKSLKEA
FDPLDISDWN SIFWIVHPGG PAILDQVEDK LALNPEKLRS TRHVLSEYGN MWSASVIFIL
DEMRKASAKD G
//
