ID C1MLI2_MICPC Unreviewed; 740 AA.
AC C1MLI2;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 24-JAN-2024, entry version 47.
DE SubName: Full=Glutamine synthase {ECO:0000313|EMBL:EEH59547.1};
GN Name=GLNA {ECO:0000313|EMBL:EEH59547.1};
GN ORFNames=MICPUCDRAFT_55724 {ECO:0000313|EMBL:EEH59547.1};
OS Micromonas pusilla (strain CCMP1545) (Picoplanktonic green alga).
OC Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales;
OC Mamiellaceae; Micromonas.
OX NCBI_TaxID=564608 {ECO:0000313|Proteomes:UP000001876};
RN [1] {ECO:0000313|EMBL:EEH59547.1, ECO:0000313|Proteomes:UP000001876}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1545 {ECO:0000313|EMBL:EEH59547.1,
RC ECO:0000313|Proteomes:UP000001876};
RX PubMed=19359590; DOI=10.1126/science.1167222;
RA Worden A.Z., Lee J.H., Mock T., Rouze P., Simmons M.P., Aerts A.L.,
RA Allen A.E., Cuvelier M.L., Derelle E., Everett M.V., Foulon E.,
RA Grimwood J., Gundlach H., Henrissat B., Napoli C., McDonald S.M.,
RA Parker M.S., Rombauts S., Salamov A., Von Dassow P., Badger J.H.,
RA Coutinho P.M., Demir E., Dubchak I., Gentemann C., Eikrem W., Gready J.E.,
RA John U., Lanier W., Lindquist E.A., Lucas S., Mayer K.F., Moreau H.,
RA Not F., Otillar R., Panaud O., Pangilinan J., Paulsen I., Piegu B.,
RA Poliakov A., Robbens S., Schmutz J., Toulza E., Wyss T., Zelensky A.,
RA Zhou K., Armbrust E.V., Bhattacharya D., Goodenough U.W., Van de Peer Y.,
RA Grigoriev I.V.;
RT "Green evolution and dynamic adaptations revealed by genomes of the marine
RT picoeukaryotes Micromonas.";
RL Science 324:268-272(2009).
CC -!- SIMILARITY: Belongs to the glutamine synthetase family.
CC {ECO:0000256|PROSITE-ProRule:PRU01331, ECO:0000256|RuleBase:RU000384}.
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DR EMBL; GG663736; EEH59547.1; -; Genomic_DNA.
DR RefSeq; XP_003056171.1; XM_003056125.1.
DR AlphaFoldDB; C1MLI2; -.
DR STRING; 564608.C1MLI2; -.
DR GeneID; 9681796; -.
DR KEGG; mpp:MICPUCDRAFT_55724; -.
DR eggNOG; ENOG502QQE3; Eukaryota.
DR OMA; QFLVFCA; -.
DR OrthoDB; 2783570at2759; -.
DR Proteomes; UP000001876; Unassembled WGS sequence.
DR GO; GO:0004356; F:glutamine synthetase activity; IEA:UniProtKB-EC.
DR GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR Gene3D; 1.20.120.1560; -; 2.
DR Gene3D; 3.30.590.10; Glutamine synthetase/guanido kinase, catalytic domain; 1.
DR InterPro; IPR040577; Gln-synt_C.
DR InterPro; IPR014746; Gln_synth/guanido_kin_cat_dom.
DR InterPro; IPR008146; Gln_synth_cat_dom.
DR InterPro; IPR027303; Gln_synth_gly_rich_site.
DR InterPro; IPR022147; GSIII_N.
DR PANTHER; PTHR42974; GLUTAMINE SYNTHETASE; 1.
DR PANTHER; PTHR42974:SF1; TYPE-3 GLUTAMINE SYNTHETASE; 1.
DR Pfam; PF00120; Gln-synt_C; 1.
DR Pfam; PF18318; Gln-synt_C-ter; 1.
DR Pfam; PF12437; GSIII_N; 1.
DR SMART; SM01230; Gln-synt_C; 1.
DR SUPFAM; SSF55931; Glutamine synthetase/guanido kinase; 1.
DR PROSITE; PS00181; GLNA_ATP; 1.
DR PROSITE; PS51987; GS_CATALYTIC; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001876}.
FT DOMAIN 230..650
FT /note="GS catalytic"
FT /evidence="ECO:0000259|PROSITE:PS51987"
SQ SEQUENCE 740 AA; 81389 MW; 426C83BBCE9F9152 CRC64;
MQAATCAISI ATAAPSSRKF SSRKMIRGSM FFRKATPLTL GTNPCAGKPF ARSRHARLVT
SAMMSVSSSP PASIEGFGDH CFKGAVAKKY LSKYGESEKL LEDPTWPRRP GKADIVAKAV
LDWAVDNGAS VFCHWFQPMA SSGVRHGLSA QVHQTMFEFD KDGKPFFKFE GEQLLQGETD
GSSYPNGGMR ATHTAGGYLS IDPLSPIFLR EDTIFIPAAF VSYNGDALDE KTPLHRATQK
MSKEGTRLLK LMGYDVDGLI NNIGLEQEIF LVPRHAFYRR PDLQFTGRTI TGKQPARGQE
MSDHYMAPIS RATTAFDCMR QIQSECFKIG IPLKTRHREV APNQYEFAPL FGNVISQTDQ
NLMVMQIIEE VASENGLAAL LQEKPFSGIN GSGKHNNWSI GTVDGVNLLN PKQINTASKN
DAVFPVIMAA LVSAIDKHGD LMRLSIASPG NDFRLGAMEA PPAVMSTYLG DDTAAAYTPS
KKKLAFGAEV ISDIEVPSED RNRTSPFPYG GSRFEFRAAG SSQNVSLVNT VLNTIAAEAF
SIVADRIESG EEPLKIAQDL LKQHSKVIFN GDGYDPEWPE KAVEKGIWRI DSGVEAIKKL
TDAKNTDLFQ KMGVLTPREC EARRTVLLEH YTATVEMEAL TLIDIINQHV IPSCKKAELN
FVKQLEDSVK SLKRSLHEIH ISSEASDAAA LARILRLDTM IKVREVCDEA ESLCPPSLWS
LATYSELLFL DTYPEGDLLL
//
