ID C1MXQ0_MICPC Unreviewed; 407 AA.
AC C1MXQ0;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 22-FEB-2023, entry version 47.
DE RecName: Full=glycerophosphodiester phosphodiesterase {ECO:0000256|ARBA:ARBA00012247};
DE EC=3.1.4.46 {ECO:0000256|ARBA:ARBA00012247};
GN ORFNames=MICPUCDRAFT_60240 {ECO:0000313|EMBL:EEH55499.1};
OS Micromonas pusilla (strain CCMP1545) (Picoplanktonic green alga).
OC Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales;
OC Mamiellaceae; Micromonas.
OX NCBI_TaxID=564608 {ECO:0000313|Proteomes:UP000001876};
RN [1] {ECO:0000313|EMBL:EEH55499.1, ECO:0000313|Proteomes:UP000001876}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1545 {ECO:0000313|EMBL:EEH55499.1,
RC ECO:0000313|Proteomes:UP000001876};
RX PubMed=19359590; DOI=10.1126/science.1167222;
RA Worden A.Z., Lee J.H., Mock T., Rouze P., Simmons M.P., Aerts A.L.,
RA Allen A.E., Cuvelier M.L., Derelle E., Everett M.V., Foulon E.,
RA Grimwood J., Gundlach H., Henrissat B., Napoli C., McDonald S.M.,
RA Parker M.S., Rombauts S., Salamov A., Von Dassow P., Badger J.H.,
RA Coutinho P.M., Demir E., Dubchak I., Gentemann C., Eikrem W., Gready J.E.,
RA John U., Lanier W., Lindquist E.A., Lucas S., Mayer K.F., Moreau H.,
RA Not F., Otillar R., Panaud O., Pangilinan J., Paulsen I., Piegu B.,
RA Poliakov A., Robbens S., Schmutz J., Toulza E., Wyss T., Zelensky A.,
RA Zhou K., Armbrust E.V., Bhattacharya D., Goodenough U.W., Van de Peer Y.,
RA Grigoriev I.V.;
RT "Green evolution and dynamic adaptations revealed by genomes of the marine
RT picoeukaryotes Micromonas.";
RL Science 324:268-272(2009).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a sn-glycero-3-phosphodiester + H2O = an alcohol + H(+) + sn-
CC glycerol 3-phosphate; Xref=Rhea:RHEA:12969, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:30879, ChEBI:CHEBI:57597,
CC ChEBI:CHEBI:83408; EC=3.1.4.46;
CC Evidence={ECO:0000256|ARBA:ARBA00029315};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GG663742; EEH55499.1; -; Genomic_DNA.
DR RefSeq; XP_003060730.1; XM_003060684.1.
DR AlphaFoldDB; C1MXQ0; -.
DR STRING; 564608.C1MXQ0; -.
DR GeneID; 9685874; -.
DR KEGG; mpp:MICPUCDRAFT_60240; -.
DR eggNOG; KOG2258; Eukaryota.
DR OMA; CPECVYW; -.
DR OrthoDB; 646258at2759; -.
DR Proteomes; UP000001876; Unassembled WGS sequence.
DR GO; GO:0008889; F:glycerophosphodiester phosphodiesterase activity; IEA:UniProtKB-EC.
DR GO; GO:0006071; P:glycerol metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.190; Phosphatidylinositol (PI) phosphodiesterase; 2.
DR InterPro; IPR044236; GDPD4.
DR InterPro; IPR030395; GP_PDE_dom.
DR InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR PANTHER; PTHR47449; GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE GDPD4; 1.
DR PANTHER; PTHR47449:SF2; GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE GDPD4; 1.
DR Pfam; PF03009; GDPD; 1.
DR Pfam; PF13653; GDPD_2; 1.
DR SUPFAM; SSF51695; PLC-like phosphodiesterases; 1.
DR PROSITE; PS51704; GP_PDE; 1.
PE 4: Predicted;
KW Glycerol metabolism {ECO:0000256|ARBA:ARBA00022798};
KW Reference proteome {ECO:0000313|Proteomes:UP000001876};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..407
FT /note="glycerophosphodiester phosphodiesterase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002910551"
FT DOMAIN 53..368
FT /note="GP-PDE"
FT /evidence="ECO:0000259|PROSITE:PS51704"
FT REGION 375..407
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 407 AA; 42318 MW; BAD9511108AE75FE CRC64;
MYALVVVLAW YVSGGRTAPS PVASSSSSSP VVLAPSPTFC ARRDPIVCAH GTVGSADWPR
SMGRRPFPNT VPALAAAVAA GHECVEVDAS RTKDDHLVAL HPRELKMLTG GRVGNPGDLT
LAEIMSLTMP GAKEYRVATF AEAMAVVMNK GLTQITVDFK DGPPRREEGF ASAVTREIAR
LGRSHGSGRS QSATTACPEC VYWGKSDEIA LDVLELTRGD AKARLSRAFL SAHPTVSFNP
DTPRCLSTPL LTPFDSTPTS PRMHPTLARP KVGYSVANFS RAIIDAGLHR LAGREDVTSR
AYVAAAQSEM ASEALIAEVA AATAEDAPHG KTRTYAWTVN APAATAAVVN AGVDGVVTDE
PELVARVVRK LRGRCGSGGG GDGGGGGSGG GGWFARGASS AAKDEAR
//
