ID C1N5V0_MICPC Unreviewed; 856 AA.
AC C1N5V0;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=acylaminoacyl-peptidase {ECO:0000256|ARBA:ARBA00012917};
DE EC=3.4.19.1 {ECO:0000256|ARBA:ARBA00012917};
GN ORFNames=MICPUCDRAFT_53049 {ECO:0000313|EMBL:EEH52564.1};
OS Micromonas pusilla (strain CCMP1545) (Picoplanktonic green alga).
OC Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales;
OC Mamiellaceae; Micromonas.
OX NCBI_TaxID=564608 {ECO:0000313|Proteomes:UP000001876};
RN [1] {ECO:0000313|EMBL:EEH52564.1, ECO:0000313|Proteomes:UP000001876}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1545 {ECO:0000313|EMBL:EEH52564.1,
RC ECO:0000313|Proteomes:UP000001876};
RX PubMed=19359590; DOI=10.1126/science.1167222;
RA Worden A.Z., Lee J.H., Mock T., Rouze P., Simmons M.P., Aerts A.L.,
RA Allen A.E., Cuvelier M.L., Derelle E., Everett M.V., Foulon E.,
RA Grimwood J., Gundlach H., Henrissat B., Napoli C., McDonald S.M.,
RA Parker M.S., Rombauts S., Salamov A., Von Dassow P., Badger J.H.,
RA Coutinho P.M., Demir E., Dubchak I., Gentemann C., Eikrem W., Gready J.E.,
RA John U., Lanier W., Lindquist E.A., Lucas S., Mayer K.F., Moreau H.,
RA Not F., Otillar R., Panaud O., Pangilinan J., Paulsen I., Piegu B.,
RA Poliakov A., Robbens S., Schmutz J., Toulza E., Wyss T., Zelensky A.,
RA Zhou K., Armbrust E.V., Bhattacharya D., Goodenough U.W., Van de Peer Y.,
RA Grigoriev I.V.;
RT "Green evolution and dynamic adaptations revealed by genomes of the marine
RT picoeukaryotes Micromonas.";
RL Science 324:268-272(2009).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Cleavage of an N-acetyl or N-formyl amino acid from the N-
CC terminus of a polypeptide.; EC=3.4.19.1;
CC Evidence={ECO:0000256|ARBA:ARBA00000721};
CC -!- SUBUNIT: Homotetramer. {ECO:0000256|ARBA:ARBA00011881}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; GG663748; EEH52564.1; -; Genomic_DNA.
DR RefSeq; XP_003063428.1; XM_003063382.1.
DR AlphaFoldDB; C1N5V0; -.
DR STRING; 564608.C1N5V0; -.
DR GeneID; 9688660; -.
DR KEGG; mpp:MICPUCDRAFT_53049; -.
DR eggNOG; KOG2100; Eukaryota.
DR OMA; QEIATPF; -.
DR OrthoDB; 2877590at2759; -.
DR Proteomes; UP000001876; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR045550; AARE_N.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001375; Peptidase_S9.
DR PANTHER; PTHR42776:SF4; ACYLAMINO-ACID-RELEASING ENZYME; 1.
DR PANTHER; PTHR42776; SERINE PEPTIDASE S9 FAMILY MEMBER; 1.
DR Pfam; PF19283; APEH_N; 1.
DR Pfam; PF00326; Peptidase_S9; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000001876}.
FT DOMAIN 21..323
FT /note="Acylamino-acid-releasing enzyme N-terminal"
FT /evidence="ECO:0000259|Pfam:PF19283"
FT DOMAIN 629..848
FT /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT /evidence="ECO:0000259|Pfam:PF00326"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 71..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 206..227
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 325..360
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 856 AA; 89178 MW; 1478FDF65AC68759 CRC64;
MEATAATASD ADADADADAA EVERETSLFE SFTAIPSMAG AVLAPDVSDA SRSSLVAHVA
TTQRDLAGNR ARTSVASISG VPRDAPPSRP LTHPAFGIEE RGVLLSSISP SGTKRLVVRG
GKDLTNGGSD RDGCVALELW SHGALTRETL VPAKTHGAVC ADGTFGGVSW SAREGRIAYV
AEAPVGEDGP TPEWGMGVTT TTTAAKKKES EDAAAASNKK GWRGRGEWRE EWGEQLVGKT
SPACFVLECA TGEVTEVSRV GLPEGSVAAS GPIWAPADED DESDALVLPT WSGDIENFKS
TSRRLGLTFC FNRPSEMFLM DVPAPRVPAG SGAGGEKTPT PTPTPTPTKK KNPAPPTRLA
KGDVSALWPR FTPDGTALVF ISHAAAVESG AHNATCALRK IAWTPGVGPQ SEASDVVVPV
VRTPLTSTAS DADGASDALD DAFPGLYVSS PPPRTPFTDD GARMILQSTW GPGEAIVSID
MRLGKARRLT PGARDGGGSW TVCDVASGGA VGGTQVVAAA HSSPGTPPRV HLAWVTDRDA
DADATTPTRW CPVKGAHGAS STAASDASRA LETLEYLVDA VAIDDDGIGI SRVESITVRP
KAAAPRALPT IILPHGGPHA ACGAGYVATV AYLASLGYAV VYCNYRGSTG YGEDFLQARS
ALVGGGAGRM DVDDCVAIAR RAIDAGVADA NKIVVVGGSH GGFLGAHLVG QRPEMFKAAV
LRNPVTDVAS MVSLTDIPDW CFVETLGKDA FSDLPTVEQL AVMREKSPVR YVKDVRAPVL
MLLGAVDLRR VLPMVPPTNG LRYAAALREA GGRCDVRVFP EDSHGLTLPR TEFESFVTVA
KFLREALREG ALERED
//
