ID C2E6I0_LACJH Unreviewed; 374 AA.
AC C2E6I0;
DT 16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT 16-JUN-2009, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=THUMP domain-containing protein {ECO:0000259|PROSITE:PS51165};
GN ORFNames=HMPREF0528_1354 {ECO:0000313|EMBL:EEJ59547.1};
OS Lactobacillus johnsonii ATCC 33200.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=525330 {ECO:0000313|EMBL:EEJ59547.1, ECO:0000313|Proteomes:UP000003491};
RN [1] {ECO:0000313|EMBL:EEJ59547.1, ECO:0000313|Proteomes:UP000003491}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33200 {ECO:0000313|EMBL:EEJ59547.1,
RC ECO:0000313|Proteomes:UP000003491};
RA Qin X., Bachman B., Battles P., Bell A., Bess C., Bickham C., Chaboub L.,
RA Chen D., Coyle M., Deiros D.R., Dinh H., Forbes L., Fowler G.,
RA Francisco L., Fu Q., Gubbala S., Hale W., Han Y., Hemphill L.,
RA Highlander S.K., Hirani K., Hogues M., Jackson L., Jakkamsetti A.,
RA Javaid M., Jiang H., Korchina V., Kovar C., Lara F., Lee S., Mata R.,
RA Mathew T., Moen C., Morales K., Munidasa M., Nazareth L., Ngo R.,
RA Nguyen L., Okwuonu G., Ongeri F., Patil S., Petrosino J., Pham C., Pham P.,
RA Pu L.-L., Puazo M., Raj R., Reid J., Rouhana J., Saada N., Shang Y.,
RA Simmons D., Thornton R., Warren J., Weissenberger G., Zhang J., Zhang L.,
RA Zhou C., Zhu D., Muzny D., Worley K., Gibbs R.;
RL Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEJ59547.1}.
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DR EMBL; ACGR01000038; EEJ59547.1; -; Genomic_DNA.
DR RefSeq; WP_004894878.1; NZ_GG670120.1.
DR AlphaFoldDB; C2E6I0; -.
DR HOGENOM; CLU_032119_3_1_9; -.
DR Proteomes; UP000003491; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0034470; P:ncRNA processing; IEA:UniProt.
DR GO; GO:0009451; P:RNA modification; IEA:UniProt.
DR CDD; cd11715; THUMP_AdoMetMT; 1.
DR Gene3D; 3.30.2130.30; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR004114; THUMP_dom.
DR PANTHER; PTHR47313; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K/L; 1.
DR PANTHER; PTHR47313:SF1; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K_L; 1.
DR Pfam; PF02926; THUMP; 1.
DR Pfam; PF01170; UPF0020; 1.
DR SMART; SM00981; THUMP; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
DR PROSITE; PS51165; THUMP; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00529};
KW Transferase {ECO:0000256|ARBA:ARBA00022603}.
FT DOMAIN 44..155
FT /note="THUMP"
FT /evidence="ECO:0000259|PROSITE:PS51165"
SQ SEQUENCE 374 AA; 42723 MW; A4B8285B0DB05E4A CRC64;
MKEYKLYATM GAGFESVVAK ELNNLGYETT TENGRVFFKG TQKDIVRTNL WLRSADRVKI
LLKEFKATSF DQLYDEVYSY DWAELLPVDA QFPVKGRSVR SKLHSEPDVQ SIVKKAIVDK
LTDQYRRRGF LPESGAEYPL DIHLHKDTAR LSLDTTGQSL FKRGYRVEHG GAPLKENFAA
GLIELTPFDG SHPFIDPMTG SGTIAIEAAL RAKNVAPGIW RKFAFDNFDW FDKKLHPELV
EEAKAQEKKE HATILASDID QSILEIAKVN AHNAGVLQDI KFKQVAVKDF STDLENGVIV
ANPPYGKRLK DREAAEKIYE EMGQTLRPLT SFSQYYLTSD PQFEKYFGAK ATKKRKFYNG
NLRTDYYQYW ANKR
//
