ID C2EU32_9LACO Unreviewed; 1256 AA.
AC C2EU32;
DT 16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT 16-JUN-2009, sequence version 1.
DT 24-JAN-2024, entry version 73.
DE SubName: Full=Gram-positive signal peptide protein, YSIRK family {ECO:0000313|EMBL:EEJ40564.1};
GN ORFNames=HMPREF0549_0968 {ECO:0000313|EMBL:EEJ40564.1};
OS Limosilactobacillus vaginalis DSM 5837 = ATCC 49540.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Limosilactobacillus.
OX NCBI_TaxID=1423814 {ECO:0000313|EMBL:EEJ40564.1, ECO:0000313|Proteomes:UP000004483};
RN [1] {ECO:0000313|EMBL:EEJ40564.1, ECO:0000313|Proteomes:UP000004483}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49540 {ECO:0000313|EMBL:EEJ40564.1,
RC ECO:0000313|Proteomes:UP000004483};
RA Qin X., Bachman B., Battles P., Bell A., Bess C., Bickham C., Chaboub L.,
RA Chen D., Coyle M., Deiros D.R., Dinh H., Forbes L., Fowler G.,
RA Francisco L., Fu Q., Gubbala S., Hale W., Han Y., Hemphill L.,
RA Highlander S.K., Hirani K., Hogues M., Jackson L., Jakkamsetti A.,
RA Javaid M., Jiang H., Korchina V., Kovar C., Lara F., Lee S., Mata R.,
RA Mathew T., Moen C., Morales K., Munidasa M., Nazareth L., Ngo R.,
RA Nguyen L., Okwuonu G., Ongeri F., Patil S., Petrosino J., Pham C., Pham P.,
RA Pu L.-L., Puazo M., Raj R., Reid J., Rouhana J., Saada N., Shang Y.,
RA Simmons D., Thornton R., Warren J., Weissenberger G., Zhang J., Zhang L.,
RA Zhou C., Zhu D., Muzny D., Worley K., Gibbs R.;
RL Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEJ40564.1}.
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DR EMBL; ACGV01000123; EEJ40564.1; -; Genomic_DNA.
DR RefSeq; WP_003716235.1; NZ_GG693412.1.
DR AlphaFoldDB; C2EU32; -.
DR STRING; 1423814.HMPREF0549_0968; -.
DR PATRIC; fig|1423814.6.peg.29; -.
DR eggNOG; COG4932; Bacteria.
DR HOGENOM; CLU_265256_0_0_9; -.
DR OrthoDB; 2282350at2; -.
DR Proteomes; UP000004483; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR019931; LPXTG_anchor.
DR InterPro; IPR005877; YSIRK_signal_dom.
DR NCBIfam; TIGR01168; YSIRK_signal; 1.
DR Pfam; PF00746; Gram_pos_anchor; 1.
DR Pfam; PF04650; YSIRK_signal; 1.
PE 4: Predicted;
KW Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW Secreted {ECO:0000256|ARBA:ARBA00022512};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1227..1246
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 20..42
FT /note="YSIRK Gram-positive signal peptide"
FT /evidence="ECO:0000259|Pfam:PF04650"
FT DOMAIN 1212..1256
FT /note="Gram-positive cocci surface proteins LPxTG"
FT /evidence="ECO:0000259|Pfam:PF00746"
FT REGION 50..144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1118..1226
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..130
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1126..1161
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1175..1189
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1195..1226
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1256 AA; 135695 MW; CAE5D5E33C19CD7C CRC64;
MNKRIDKKRK KLIVNTSKVK QRFGIRKLTT GVTSVLLGAF LIWGGGATAQ AAEGTPTNDN
EESSNISNDS SNIKDVKEVT LPTSQESADK TNVAPSTTNS PQEAEQPAPT TINEKKSDKA
VVQSSNVANK EDESANKDQD YEDKQSSILK IQNNQQINSN ILKKNLTESK VEDSLKDFHF
TGAISSFKNT TAGKDENYLT FKDGDTAEIA YQIQGFGGTG SKSGFFYDTP NSYLLLIPKG
FVADGKVTAS YAYGNYTISS QEVLHGIGKN GEDYIKINCP NTPYYGAPVA AKINLTAKLK
EDDGGYVSYN NSLPSPFMAI NNGSFSSSND VQLGNTTYHI ANNEWDQNLN YTLIPGKQAL
DSNNFNISSS TVELHPGDTT NSGYEQLNAT INLTHHVENG DYLDFHLGLP LQDGKILPYD
TQLSDGFDAK YQGTTIGHVF KMDGYYRLVF NTAVNQFFGN SGSSFTDTFH LKWNSGTANP
AIRKPTSVTD HNFGKPFVYQ YTSDKNQNQE LFGYTPTNDV NIGGKVSASG LTIGGQYIYH
GKILQCNQSN GSSVVFSINR IWDKNNHVQI YTNWYNNEAV SIAIKAKDPS KSASNNFAIT
VIVGQNPYLT YNWTSDTDLA NQIKKTIAYY HTHELSNPIQ NDNNILTQDK DTKGAQLPDG
SVTVTHEEKI ENGVVTRTYH VKISNPEVEL DGAISPLGVS ASGFTMPDNI RSYSEDVANA
EANKKGNFGG TDDLSANTSN ETLKKALEDT DTIKVAISNE SETTSKNVSG VLGSPWFAKI
GYSGSNLGPN GDDPSNYITT KLIFKDDSGN VVGPSDGFKF QGKSGTTISF NGVEQELVDL
INQGYNIDHV ASKSGNTETT ISPSGDKNKI SSYNFGNIST ASATPDEFIV YLKASHAPIT
DTSKKVTETV HYIFQDENGQ VLNTPTRDDH HAELDFTGTK PYGSKDSDPF TYDDGKTFNA
VTIDPQLGFK LISAKTADGT DVLDGNSEGI NHNTPNVVVN VIFKAQPQAD LTDTKNVTET
IKYVFQDANG HVITSTSRKA DSQTLTFTGT RADKNDQFAY DEPKSFDAVA IAAQAGFDLI
SATNDASHAD VLGDNAVKQI AGIKHDSAPV NITVVFKAQP QNNPGGNPQP STPDKPVTPV
QPSTPNTPET PVVPTTPDVP GTTPETPTTN PEVPGTPSVP NTSEAPHKQE VTVDTTKVSE
TPVQNIGEST ETKQQGQKLP QTSNQNGSHL ALAGLAVTAI ASLFGITGER KRKGKN
//
