ID C2KHN9_LEUMC Unreviewed; 375 AA.
AC C2KHN9;
DT 16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT 16-JUN-2009, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE SubName: Full=Methionine synthase, vitamin-B12 independent {ECO:0000313|EMBL:EEJ43232.1};
DE EC=2.1.1.14 {ECO:0000313|EMBL:EEJ43232.1};
GN ORFNames=HMPREF0555_0155 {ECO:0000313|EMBL:EEJ43232.1};
OS Leuconostoc mesenteroides subsp. cremoris ATCC 19254.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Leuconostoc.
OX NCBI_TaxID=586220 {ECO:0000313|EMBL:EEJ43232.1, ECO:0000313|Proteomes:UP000004283};
RN [1] {ECO:0000313|EMBL:EEJ43232.1, ECO:0000313|Proteomes:UP000004283}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19254 {ECO:0000313|EMBL:EEJ43232.1,
RC ECO:0000313|Proteomes:UP000004283};
RA Qin X., Bachman B., Battles P., Bell A., Bess C., Bickham C., Chaboub L.,
RA Chen D., Coyle M., Deiros D.R., Dinh H., Forbes L., Fowler G.,
RA Francisco L., Fu Q., Gubbala S., Hale W., Han Y., Hemphill L.,
RA Highlander S.K., Hirani K., Hogues M., Jackson L., Jakkamsetti A.,
RA Javaid M., Jiang H., Korchina V., Kovar C., Lara F., Lee S., Mata R.,
RA Mathew T., Moen C., Morales K., Munidasa M., Nazareth L., Ngo R.,
RA Nguyen L., Okwuonu G., Ongeri F., Patil S., Petrosino J., Pham C., Pham P.,
RA Pu L.-L., Puazo M., Raj R., Reid J., Rouhana J., Saada N., Shang Y.,
RA Simmons D., Thornton R., Warren J., Weissenberger G., Zhang J., Zhang L.,
RA Zhou C., Zhu D., Muzny D., Worley K., Gibbs R.;
RL Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEJ43232.1}.
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DR EMBL; ACKV01000007; EEJ43232.1; -; Genomic_DNA.
DR RefSeq; WP_002815826.1; NZ_GG693387.1.
DR AlphaFoldDB; C2KHN9; -.
DR HOGENOM; CLU_058877_0_0_9; -.
DR Proteomes; UP000004283; Unassembled WGS sequence.
DR GO; GO:0003871; F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0009086; P:methionine biosynthetic process; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd03311; CIMS_C_terminal_like; 1.
DR Gene3D; 3.20.20.210; -; 1.
DR InterPro; IPR002629; Met_Synth_C/arc.
DR InterPro; IPR038071; UROD/MetE-like_sf.
DR PANTHER; PTHR43844; METHIONINE SYNTHASE; 1.
DR PANTHER; PTHR43844:SF1; METHIONINE SYNTHASE; 1.
DR Pfam; PF01717; Meth_synt_2; 2.
DR SUPFAM; SSF51726; UROD/MetE-like; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:EEJ43232.1};
KW Transferase {ECO:0000313|EMBL:EEJ43232.1}.
FT DOMAIN 14..72
FT /note="Cobalamin-independent methionine synthase MetE C-
FT terminal/archaeal"
FT /evidence="ECO:0000259|Pfam:PF01717"
FT DOMAIN 169..349
FT /note="Cobalamin-independent methionine synthase MetE C-
FT terminal/archaeal"
FT /evidence="ECO:0000259|Pfam:PF01717"
SQ SEQUENCE 375 AA; 42038 MW; 6150AFEDC2875922 CRC64;
MTTQTLKALG FQHVGSFLRP AELKQARQDF EAGKLTQEEL EGVENSTIAH LVDQQVAAGI
AVVTDGEFRR SYWHLDNFWG FGGVERLSYG EGYFFAHEET RDDSARLNGK LSFDANVHPF
IKHFKFLKAL ADEAGVEAKI TIPAPSQFYA ELVRGTNADV VSNFYDSDQE FFADIKRVYH
EEIIALYEAG AKTVQLDDCT WGMLVDADFW EKMAGSGFDV KQLKALYLDL NNGAIANLPE
DLTINTHICR GNYHSDWAAS GGYDAVADEL FGQENVSSYF LEYDSERAGG FEPLAKVSGD
KKVVLGLITT KTGELEKKED IIKRIHEAEK YLPLDRLWLS TQCGFASTEE GNILTEEQQW
AKLALVKEIL DEVWG
//
