ID C2MB66_9PORP Unreviewed; 350 AA.
AC C2MB66;
DT 16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT 16-JUN-2009, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Efflux transporter, RND family, MFP subunit {ECO:0000313|EMBL:EEK17027.1};
GN ORFNames=PORUE0001_0112 {ECO:0000313|EMBL:EEK17027.1};
OS Porphyromonas uenonis 60-3.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Porphyromonadaceae;
OC Porphyromonas.
OX NCBI_TaxID=596327 {ECO:0000313|EMBL:EEK17027.1, ECO:0000313|Proteomes:UP000003303};
RN [1] {ECO:0000313|EMBL:EEK17027.1, ECO:0000313|Proteomes:UP000003303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=60-3 {ECO:0000313|EMBL:EEK17027.1,
RC ECO:0000313|Proteomes:UP000003303};
RA Sebastian Y., Madupu R., Durkin A.S., Torralba M., Methe B., Sutton G.G.,
RA Strausberg R.L., Nelson K.E.;
RL Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEK17027.1}.
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DR EMBL; ACLR01000120; EEK17027.1; -; Genomic_DNA.
DR RefSeq; WP_007365172.1; NZ_ACLR01000120.1.
DR AlphaFoldDB; C2MB66; -.
DR STRING; 596327.PORUE0001_0112; -.
DR eggNOG; COG0845; Bacteria.
DR OrthoDB; 9798190at2; -.
DR Proteomes; UP000003303; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0042221; P:response to chemical; IEA:UniProt.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 2.
DR InterPro; IPR043602; CusB_dom_1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF15; HLYD FAMILY OF SECRETION PROTEINS; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF00529; CusB_dom_1; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..350
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002916496"
FT DOMAIN 70..264
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT DOMAIN 265..331
FT /note="Cation efflux system protein CusB"
FT /evidence="ECO:0000259|Pfam:PF00529"
SQ SEQUENCE 350 AA; 38524 MW; 1BB95BCC0391358D CRC64;
MFLSIRTVAP IALSLALLSL TSCHSASKDG KTSFSHTIDS TDIKHVEVAT VSVQTLPDLQ
EYTSTVEAKV TNQIAPQMAS RIKRIYVEVG QQVSRGQLLA EMDHSQLEQA RLQVEERKSA
LARIDELYKI GGISQSEWEA TRRALTLAQT SYNNIKENTQ LRSPISGVVT ARNYDAGDMM
SPQMPLLVVE RVNPVVLRVN PSERYYGQMT KGMPVTITSE SLPDETFAGK ISLKYPTINP
QTHTFTMEIE ATNPERKLVP GQYARISINL GDKEYTVVPT ESIVKQIGSA EQCVYIVRDG
IAHRQVVLVE RTIGKYTAIS EGVSPGDVVV TTGASILSDQ MPVQVSQAQQ
//
