ID C3JVK7_RHOER Unreviewed; 979 AA.
AC C3JVK7;
DT 16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT 16-JUN-2009, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Membrane transport protein MMPL domain-containing protein {ECO:0000259|Pfam:PF03176};
GN ORFNames=RHOER0001_1011 {ECO:0000313|EMBL:EEN84679.1};
OS Rhodococcus erythropolis SK121.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Rhodococcus; Rhodococcus erythropolis group.
OX NCBI_TaxID=596309 {ECO:0000313|EMBL:EEN84679.1, ECO:0000313|Proteomes:UP000005836};
RN [1] {ECO:0000313|EMBL:EEN84679.1, ECO:0000313|Proteomes:UP000005836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK121 {ECO:0000313|EMBL:EEN84679.1,
RC ECO:0000313|Proteomes:UP000005836};
RA Sebastian Y., Madupu R., Durkin A.S., Torralba M., Methe B., Sutton G.G.,
RA Strausberg R.L., Nelson K.E.;
RL Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEN84679.1}.
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DR EMBL; ACNO01000104; EEN84679.1; -; Genomic_DNA.
DR RefSeq; WP_003945776.1; NZ_ACNO01000104.1.
DR AlphaFoldDB; C3JVK7; -.
DR Proteomes; UP000005836; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 194..227
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..260
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 315..340
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 379..402
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 522..544
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 551..570
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 582..601
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 636..655
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 44..378
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
FT DOMAIN 489..697
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
FT REGION 746..770
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 804..979
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 750..768
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 865..913
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 930..944
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 946..960
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 979 AA; 103381 MW; EDA7F5A5D22DEDD9 CRC64;
MFASWGSIVY RARFTVIAVM VAGLLGLAAY GLSLQDHLSQ SGWDDPGSES VEAAKLADGT
FGRSTTGDVL ALYTAPEGKT VDDPEFQAKV IDNLQRLVAD NPDQIMKING SYFKVDNGLS
VAALADKTKQ HAVTSIAIAG DNDTAVSNNF RDVESQFYID GVDVQLAGLQ PVANSLNDTM
ANDIKRMEML AIPAVGVLLF FVFGGVVAAA LPLIVGGLTV IGANGIIRLI TNFTEVNAFV
APVVSLVGLG LAIDYGLFIV SRFREEIAEG YDTPTAVRRT VMTAGRTVMF SATMVAVSLG
GLLLFPQGFL KSVAYGAIAA VMLAAISSIT ILPAILGILG KRIDALTFKK LRQTKTNEEI
ENGFWGKLTR WVMQHPLKVA VPIVAALLLM IIPLTGIKFG GINETYLPPD SPTRVAQAQF
DELFPGNRTE PVRLVIEGAD NTTLGQISKT ANAAPGLVEK FTPEVATKDG VNVLKAGLTE
RNEARPTIDY LRSADWPEGT TVLVGGTPAI EQDSVDALLD RLPLMVVSVI LLTTLLMFLT
FGSLVLPIKA ALMSALGLGS TLGILTWIFI DGHGSGLLNF TPGPIMSPVL VLIIAIVYGL
STDYEVFLLS RMVEARAQGA STTESIRIGT AHTGRIITAA ALILIVVTGA FGLSDLVMMK
YISYGMISAL IIDATLIRMF LVPATMKLLG DDCWWAPAWM KRIQQKIGLG EPILDNELVL
ANVPQIAPVG AIAGPGQPRK IEAASRVMPP PAPAAQPESG PRVPDPLTEP IPLSEMAIKA
PNTEAPAAEK PAPRRRLDIG SAASAPQNLI EAPVPNPSYR PQPNASDKRR NPTPAAPAER
PIESWLSDLR AREQTPPASR PLPVVRTPSR TNGSATNGAA SSSSGSNGAS RNGSANGATN
GSATNGSAPT SVEATPQSPP PPTAPERRNG VFTESPSPTN EPRVSDATPD GDDNATGRHR
PDDAGAISVS ELIARQKRS
//
