ID C3KRY6_SINFN Unreviewed; 518 AA.
AC C3KRY6;
DT 16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT 16-JUN-2009, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE SubName: Full=Phosphomannomutase/phosphoglucomutase {ECO:0000313|EMBL:ACP22844.1};
DE EC=5.4.2.8 {ECO:0000313|EMBL:ACP22844.1};
GN Name=manB {ECO:0000313|EMBL:ACP22844.1};
GN OrderedLocusNames=NGR_b13930 {ECO:0000313|EMBL:ACP22844.1};
OS Sinorhizobium fredii (strain NBRC 101917 / NGR234).
OG Plasmid sym pNGR234b {ECO:0000313|Proteomes:UP000001054}.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX NCBI_TaxID=394 {ECO:0000313|EMBL:ACP22844.1, ECO:0000313|Proteomes:UP000001054};
RN [1] {ECO:0000313|Proteomes:UP000001054}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 101917 / NGR234 {ECO:0000313|Proteomes:UP000001054};
RX PubMed=14702322; DOI=10.1128/JB.186.2.535-542.2004;
RA Streit W.R., Schmitz R.A., Perret X., Staehelin C., Deakin W.J., Raasch C.,
RA Liesegang H., Broughton W.J.;
RT "An evolutionary hot spot: the pNGR234b replicon of Rhizobium sp. strain
RT NGR234.";
RL J. Bacteriol. 186:535-542(2004).
RN [2] {ECO:0000313|EMBL:ACP22844.1, ECO:0000313|Proteomes:UP000001054}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 101917 / NGR234 {ECO:0000313|Proteomes:UP000001054};
RX PubMed=19376903; DOI=10.1128/AEM.00515-09;
RA Schmeisser C., Liesegang H., Krysciak D., Bakkou N., Le Quere A.,
RA Wollherr A., Heinemeyer I., Morgenstern B., Pommerening-Roeser A.,
RA Flores M., Palacios R., Brenner S., Gottschalk G., Schmitz R.A.,
RA Broughton W.J., Perret X., Strittmatter A.W., Streit W.R.;
RT "Rhizobium sp. strain NGR234 possesses a remarkable number of secretion
RT systems.";
RL Appl. Environ. Microbiol. 75:4035-4045(2009).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the phosphohexose mutase family.
CC {ECO:0000256|ARBA:ARBA00010231}.
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DR EMBL; CP000874; ACP22844.1; -; Genomic_DNA.
DR RefSeq; WP_015887485.1; NC_012586.1.
DR RefSeq; YP_002823597.1; NC_012586.1.
DR AlphaFoldDB; C3KRY6; -.
DR KEGG; rhi:NGR_b13930; -.
DR PATRIC; fig|394.7.peg.1796; -.
DR HOGENOM; CLU_016950_9_1_5; -.
DR OrthoDB; 9803322at2; -.
DR Proteomes; UP000001054; Plasmid sym pNGR234b.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004615; F:phosphomannomutase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd03089; PMM_PGM; 1.
DR Gene3D; 3.40.120.10; Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3; 3.
DR Gene3D; 3.30.310.50; Alpha-D-phosphohexomutase, C-terminal domain; 1.
DR InterPro; IPR005844; A-D-PHexomutase_a/b/a-I.
DR InterPro; IPR016055; A-D-PHexomutase_a/b/a-I/II/III.
DR InterPro; IPR005845; A-D-PHexomutase_a/b/a-II.
DR InterPro; IPR005846; A-D-PHexomutase_a/b/a-III.
DR InterPro; IPR005843; A-D-PHexomutase_C.
DR InterPro; IPR036900; A-D-PHexomutase_C_sf.
DR InterPro; IPR005841; Alpha-D-phosphohexomutase_SF.
DR PANTHER; PTHR43771:SF2; PHOSPHOGLUCOMUTASE; 1.
DR PANTHER; PTHR43771; PHOSPHOMANNOMUTASE; 1.
DR Pfam; PF02878; PGM_PMM_I; 1.
DR Pfam; PF02879; PGM_PMM_II; 1.
DR Pfam; PF02880; PGM_PMM_III; 1.
DR Pfam; PF00408; PGM_PMM_IV; 1.
DR PRINTS; PR00509; PGMPMM.
DR SUPFAM; SSF55957; Phosphoglucomutase, C-terminal domain; 1.
DR SUPFAM; SSF53738; Phosphoglucomutase, first 3 domains; 3.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:ACP22844.1};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Plasmid {ECO:0000313|EMBL:ACP22844.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001054}.
FT DOMAIN 40..177
FT /note="Alpha-D-phosphohexomutase alpha/beta/alpha"
FT /evidence="ECO:0000259|Pfam:PF02878"
FT DOMAIN 195..291
FT /note="Alpha-D-phosphohexomutase alpha/beta/alpha"
FT /evidence="ECO:0000259|Pfam:PF02879"
FT DOMAIN 297..407
FT /note="Alpha-D-phosphohexomutase alpha/beta/alpha"
FT /evidence="ECO:0000259|Pfam:PF02880"
FT DOMAIN 447..505
FT /note="Alpha-D-phosphohexomutase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00408"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 518 AA; 56378 MW; F5C641F77EF87CCC CRC64;
MAQVEFARID PGSSYEPLHE SGPDRFTLET SALIRPTGFR EYDARWWFGR PDDGKAPDLN
LMGVQALGMG LGTFMRRSGA GPEIVTGHDF RSYSLGIKLA LVSGLLAAGA RVRDIGLALS
PMAYFAQFAL DVPSVAMVTA SHNENGWTGV KMGTARPLTF GPDEMAELKR IVLEADFDLT
GGGAYEFIAD FRQRYIDDLT RDRRIARKLK VVVACGNGTA GAFAPHVLER IGCEVIPLDC
ELDHSFPHYN PNPEDLAMLH AIRDKVLESG ADVGLGFDGD GDRCGVVDNE GREIFADKIG
VMLARDLSAL HPNSVFVVDV KSTGLFASDP VLKASGAHTD YWKTGHSYIK RRVAELGALA
GFEKSGHFFF NPPLGRGYDD GLITALAVCE MLDRNPGMSM AELYRSLPVT WGSPTMSPHC
DDEVKYAVVE RVVERFRTMQ RDGLPVAGQQ IANLVTVNGV RVVVEDGTWG LVRASSNKPE
LVVVVESPVS EARQRAMFAA VDGVLREHAE VGAYNQTI
//
