ID C3N1F7_SULIA Unreviewed; 478 AA.
AC C3N1F7;
DT 16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT 16-JUN-2009, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Aldehyde Dehydrogenase {ECO:0000313|EMBL:ACP56184.1};
GN OrderedLocusNames=M1627_2325 {ECO:0000313|EMBL:ACP56184.1};
OS Sulfolobus islandicus (strain M.16.27).
OC Archaea; Thermoproteota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC Sulfolobus.
OX NCBI_TaxID=427318 {ECO:0000313|EMBL:ACP56184.1, ECO:0000313|Proteomes:UP000002307};
RN [1] {ECO:0000313|EMBL:ACP56184.1, ECO:0000313|Proteomes:UP000002307}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M.16.27 {ECO:0000313|EMBL:ACP56184.1,
RC ECO:0000313|Proteomes:UP000002307};
RX PubMed=19435847; DOI=10.1073/pnas.0808945106;
RA Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J.;
RT "Biogeography of the Sulfolobus islandicus pan-genome.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009).
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
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DR EMBL; CP001401; ACP56184.1; -; Genomic_DNA.
DR RefSeq; WP_012712204.1; NC_012632.1.
DR AlphaFoldDB; C3N1F7; -.
DR GeneID; 84059571; -.
DR KEGG; sim:M1627_2325; -.
DR HOGENOM; CLU_005391_1_0_2; -.
DR Proteomes; UP000002307; Chromosome.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd07097; ALDH_KGSADH-YcbD; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003345}.
FT DOMAIN 11..474
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 249
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 478 AA; 52204 MW; 061395F0C4FE77C3 CRC64;
MKSYQGLADK WIKGSGEEYL DINPADKDHV LAKIKLYTKD DVKEAINKAV AKFDEWSRTP
APKRGSILLK AGELMEQEAQ EFALLMTLEE GKTLKDSMFE VTRSYNLLKF YGALAFKIAG
KTLPSADPNT RIFTVKEPLG VVALITPWNF PLSIPVWKLA PALAAGNTAV IKPATKTPLM
VAKLVEVLSK AGLPEGVVNL VVGKGSEVGD IIVSDDNIAA VSFTGSTEVG KRIYKLVGNK
NRMTRIQLEL GGKNALYVDK SADLTLAAEL AVRGGFGLTG QSCTATSRLI INKDVYTQFK
QRLLERVKKW RVGPGTEDVD MGPVVDEGQF KKDLEYIEYG KNAGAKLIYG GNTVPGKGYF
LEPTIFEGVT SDMRLFKEEI FGPVLSVTEA KDLDEAIRLV NAVDYGHTAG IVASDIKAIN
EFVSRVEAGV IKVNKPTVGL ELQAPFGGFK NSGATTWKEM GEDALEFYLK EKTVYEGW
//
