ID C3QWJ6_9BACE Unreviewed; 718 AA.
AC C3QWJ6;
DT 16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT 16-JUN-2009, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE RecName: Full=Tetracycline resistance protein TetQ {ECO:0000256|ARBA:ARBA00013902};
GN ORFNames=BSCG_03256 {ECO:0000313|EMBL:EEO56330.1};
OS Bacteroides sp. 2_2_4.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=469590 {ECO:0000313|EMBL:EEO56330.1};
RN [1] {ECO:0000313|EMBL:EEO56330.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2_2_4 {ECO:0000313|EMBL:EEO56330.1};
RG The Broad Institute Genome Sequencing Platform;
RA Ward D., Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L.,
RA Berlin A., Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C.,
RA Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A.,
RA Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T.,
RA White J., Yandava C., Allen-Vercoe E., Strauss J., Ambrose C., Lander E.,
RA Nusbaum C., Ilzarbe M., Galagan J., Birren B.;
RT "The Genome Sequence of Bacteroides sp. strain 2_2_4.";
RL Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Abolishes the inhibitory effect of tetracyclin on protein
CC synthesis by a non-covalent modification of the ribosomes.
CC {ECO:0000256|ARBA:ARBA00003987}.
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DR EMBL; EQ973361; EEO56330.1; -; Genomic_DNA.
DR RefSeq; WP_004299324.1; NZ_EQ973361.1.
DR AlphaFoldDB; C3QWJ6; -.
DR GeneID; 69481588; -.
DR HOGENOM; CLU_002794_4_1_10; -.
DR Proteomes; UP000003969; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR CDD; cd04170; EF-G_bact; 1.
DR CDD; cd01434; EFG_mtEFG1_IV; 1.
DR CDD; cd03713; EFG_mtEFG_C; 1.
DR CDD; cd04088; EFG_mtEFG_II; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR041095; EFG_II.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR047872; EFG_IV.
DR InterPro; IPR035649; EFG_V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR005517; Transl_elong_EFG/EF2_IV.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43261:SF7; ELONGATION FACTOR G-LIKE PROTEIN; 1.
DR PANTHER; PTHR43261; TRANSLATION ELONGATION FACTOR G-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF14492; EFG_III; 1.
DR Pfam; PF03764; EFG_IV; 2.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SMART; SM00838; EFG_C; 1.
DR SMART; SM00889; EFG_IV; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Elongation factor {ECO:0000313|EMBL:EEO56330.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000313|EMBL:EEO56330.1}.
FT DOMAIN 7..281
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 718 AA; 80349 MW; 40ECFE4DF1686883 CRC64;
MKVYQTNEIK NIALLGSSGS GKTTLVEAML FESGVIKRRG SVAAKNTVSD YFPVEQEYGY
SVFSTVLHVE WNNKKLNIID CPGSDDFVGS TVTALNVTDT AIILLNGQYG VEVGTQNHFR
YTEKLNKPVI FLVNQLDNEK CDYDNILEQL KEAYGSKVVP IQYPIATGPG FNALIDVLLM
KKYSWKPEGG APTIEDIPAE EMDKAMEMHK ALVEAAAEND ENLMEKFFEQ DSLSEDEMRE
GIRKGLIARG MFPVFCVCGG KDMGVRRLME FLGNVVPFVS EMPKVQNTEG KEVAPDSNGP
ESLYFFKTSV EPHIGEVSYF KVMSGKVHEG DDLLNADRGS KERIAQIYVV AGGNRVKVEE
LQAGDIGAAV KLKDVKTGNT LNGKDCDYKF NFIKYPNSKY TRAIKPVNEA DVEKMMSILN
RMREEDPTWV IEQSKELKQT LVHGQGEFHL RTLKWRLENN EKLQVKYEEP KIPYRETITK
AARADYRHKK QSGGAGQFGE VHLIVEPYKE GMPVPETYKF NGQEFKITVR GTEEIPLEWG
GKLVFVNSIV GGSIDARFLP AIMKGIMSRM EQGPLTGSYA RDVRVIVYDG KMHPVDSNEI
SFMLAGRNAF SEAFKNAGPK ILEPIYDVEV FVPSDRMGDV MGDLQGRRAM IMGMSSEKGF
EKLVAKVPLK EMSSYSTALS SLTGGRASFI MKFSSYELVP TDVQDKLMKD FEAKQTEE
//
