ID   C3R3M6_9BACE            Unreviewed;       657 AA.
AC   C3R3M6;
DT   16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT   16-JUN-2009, sequence version 1.
DT   24-JAN-2024, entry version 43.
DE   RecName: Full=Alpha-glucosidase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=BSCG_05739 {ECO:0000313|EMBL:EEO58810.1};
OS   Bacteroides sp. 2_2_4.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=469590 {ECO:0000313|EMBL:EEO58810.1};
RN   [1] {ECO:0000313|EMBL:EEO58810.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2_2_4 {ECO:0000313|EMBL:EEO58810.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Ward D., Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L.,
RA   Berlin A., Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C.,
RA   Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A.,
RA   Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T.,
RA   White J., Yandava C., Allen-Vercoe E., Strauss J., Ambrose C., Lander E.,
RA   Nusbaum C., Ilzarbe M., Galagan J., Birren B.;
RT   "The Genome Sequence of Bacteroides sp. strain 2_2_4.";
RL   Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC         Evidence={ECO:0000256|ARBA:ARBA00001913};
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DR   EMBL; EQ973377; EEO58810.1; -; Genomic_DNA.
DR   RefSeq; WP_008651691.1; NZ_EQ973377.1.
DR   AlphaFoldDB; C3R3M6; -.
DR   HOGENOM; CLU_011166_0_0_10; -.
DR   Proteomes; UP000003969; Unassembled WGS sequence.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:UniProt.
DR   GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 2.70.98.10; -; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR014718; GH-type_carb-bd.
DR   InterPro; IPR029483; GH97_C.
DR   InterPro; IPR019563; GH97_catalytic.
DR   InterPro; IPR029486; GH97_N.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR35803; GLUCAN 1,4-ALPHA-GLUCOSIDASE SUSB-RELATED; 1.
DR   PANTHER; PTHR35803:SF2; RETAINING ALPHA-GALACTOSIDASE; 1.
DR   Pfam; PF14509; GH97_C; 1.
DR   Pfam; PF14508; GH97_N; 1.
DR   Pfam; PF10566; Glyco_hydro_97; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837};
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..657
FT                   /note="Alpha-glucosidase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5002931675"
FT   DOMAIN          25..289
FT                   /note="Glycosyl-hydrolase 97 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14508"
FT   DOMAIN          294..556
FT                   /note="Glycosyl-hydrolase 97 catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF10566"
FT   DOMAIN          559..653
FT                   /note="Glycosyl-hydrolase 97 C-terminal oligomerisation"
FT                   /evidence="ECO:0000259|Pfam:PF14509"
SQ   SEQUENCE   657 AA;  74748 MW;  9715F609308AF879 CRC64;
     MKRVLILLHI ILCTCIVTQA KNYTVSSPDG KTKVTVTAGK QLSWSINYNG ERILNPSLMQ
     MDIEGQTEQP GVNPKVIKAK TLKVNSEQTA VIPLKQRIIK DQYNQLTLTC KGNYAIVFRV
     YNNGAAYRFE TSLKQPKVII NTETIEQNWT EGCKLYWPRE KNQEYLTHCE AIFDELNISS
     LTNDMKGYLP IYLSTPKGTK VVIMESDLFD YPNLFLTGDR NNTLSGEFPP VVLKSALKEG
     ADRDEVLLEK ASYIAETEGT RTFPWRVLMI NEDDKAVIEN NLVYQLASPS VTQDTDWIKP
     GKISWDWWST LNVYGVDFKA GVNTDTYKYF IDFASKYGIE YILLDEGWSA GTWNIKEPIP
     GLDIPELVRY GKERNVGLVL WTLWNPLDKE LDEILDVYEK WGIKGIKVDF MQRSDQYMVN
     FYERVGKAAM ERKLLVDFHG SFKPSGLQKK YPNVMTFEGV LGLEHDKDSR DINPVHDLIL
     PFTRMVAGPM DYTPGAVNNA TAEDFYINFV HPISLGTRAH QAALYVVYES PLQMLADSPS
     NYYKAPEFAS FISRIPTIWE DTKAITAKIG EQLVIARKNG KNWYLAGLTD WNARNIEVKL
     DFLEASKYKM EIFKDGVNAD VYASDFKTEE VMVSKDELIN ITMAKGGGWA AILTPVE
//