ID C3TEZ2_ECOLX Unreviewed; 212 AA.
AC C3TEZ2;
DT 16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT 16-JUN-2009, sequence version 1.
DT 27-MAR-2024, entry version 90.
DE SubName: Full=Putative tet operon regulator {ECO:0000313|EMBL:ACI85276.1};
DE SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:QCL49100.1};
GN ORFNames=C9E67_19280 {ECO:0000313|EMBL:QCL49100.1}, ECs1259
GN {ECO:0000313|EMBL:ACI85276.1};
OS Escherichia coli.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=562 {ECO:0000313|EMBL:ACI85276.1};
RN [1] {ECO:0000313|EMBL:ACI85276.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=493/89 {ECO:0000313|EMBL:ACI85276.1}, 86-24
RC {ECO:0000313|EMBL:ACI85277.1}, 87-14 {ECO:0000313|EMBL:ACI85278.1},
RC TB182A {ECO:0000313|EMBL:ACI85279.1}, and TW14359
RC {ECO:0000313|EMBL:ACI85280.1};
RX PubMed=19439656; DOI=10.1073/pnas.0812949106;
RA Leopold S.R., Magrini V., Holt N.J., Shaikh N., Mardis E.R., Cagno J.,
RA Ogura Y., Iguchi A., Hayashi T., Mellmann A., Karch H., Besser T.E.,
RA Sawyer S.A., Whittam T.S., Tarr P.I.;
RT "A precise reconstruction of the emergence and constrained radiations of
RT Escherichia coli O157 portrayed by backbone concatenomic analysis.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:8713-8718(2009).
RN [2] {ECO:0000313|EMBL:QCL49100.1, ECO:0000313|Proteomes:UP000298553}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=143 {ECO:0000313|EMBL:QCL49100.1,
RC ECO:0000313|Proteomes:UP000298553};
RA Bono J.L., Arthur T.M.;
RT "WGA of Escherichia coli O157:H7: comparison of multiple isolates.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; EU902730; ACI85276.1; -; Genomic_DNA.
DR EMBL; EU902731; ACI85277.1; -; Genomic_DNA.
DR EMBL; EU902732; ACI85278.1; -; Genomic_DNA.
DR EMBL; EU902733; ACI85279.1; -; Genomic_DNA.
DR EMBL; EU902734; ACI85280.1; -; Genomic_DNA.
DR EMBL; CP028607; QCL49100.1; -; Genomic_DNA.
DR RefSeq; WP_001302258.1; NZ_WJRH01000001.1.
DR PATRIC; fig|562.7073.peg.2429; -.
DR OMA; DPHHLIF; -.
DR Proteomes; UP000298553; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR InterPro; IPR019915; Tscrpt_reg_pyr_util_RutR.
DR InterPro; IPR013573; Tscrpt_reg_YcdC_C.
DR NCBIfam; TIGR03613; RutR; 1.
DR PANTHER; PTHR30328:SF54; HTH-TYPE TRANSCRIPTIONAL REPRESSOR SCO4008; 1.
DR PANTHER; PTHR30328; TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF08362; TetR_C_3; 1.
DR Pfam; PF00440; TetR_N; 1.
DR PRINTS; PR00455; HTHTETR.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00335}; Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 17..77
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 40..59
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ SEQUENCE 212 AA; 23704 MW; 5DA47B85C960FD6C CRC64;
MTQGAVKTTG KRSRAVSAKK KAILSAALDT FSQFGFHGTR LEQIAELAGV SKTNLLYYFP
SKEALYIAVL RQILDIWLAP LKAFREDFAP LAAIKEYIRL KLEVSRDYPQ ASRLFCMEML
AGAPLLMDEL TGDLKSLIDE KSALIAGWVK SGKLAPIDPQ HLIFMIWAST QHYADFAPQV
EAVTGATLRD EVFFNQTVEN VQRIIIEGIR PR
//
