ID C3X9M6_OXAFO Unreviewed; 809 AA.
AC C3X9M6;
DT 16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT 16-JUN-2009, sequence version 1.
DT 24-JAN-2024, entry version 51.
DE SubName: Full=DNA internalization competence protein ComEC/Rec2-like protein {ECO:0000313|EMBL:EEO29902.1};
GN ORFNames=OFBG_00930 {ECO:0000313|EMBL:EEO29902.1};
OS Oxalobacter formigenes OXCC13.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Oxalobacteraceae; Oxalobacter.
OX NCBI_TaxID=556269 {ECO:0000313|EMBL:EEO29902.1, ECO:0000313|Proteomes:UP000005089};
RN [1] {ECO:0000313|EMBL:EEO29902.1, ECO:0000313|Proteomes:UP000005089}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OXCC13 {ECO:0000313|EMBL:EEO29902.1,
RC ECO:0000313|Proteomes:UP000005089};
RG The Broad Institute Genome Sequencing Platform;
RA Ward D., Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L.,
RA Berlin A., Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C.,
RA Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A.,
RA Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T.,
RA White J., Yandava C., Allison M.J., Lander E., Nusbaum C., Galagan J.,
RA Birren B.;
RT "The Genome Sequence of Oxalobacter formigenes OXCC13.";
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; GG658170; EEO29902.1; -; Genomic_DNA.
DR RefSeq; WP_005880684.1; NZ_GG658170.1.
DR AlphaFoldDB; C3X9M6; -.
DR STRING; 847.BRW83_1221; -.
DR GeneID; 77135105; -.
DR eggNOG; COG0658; Bacteria.
DR eggNOG; COG2333; Bacteria.
DR HOGENOM; CLU_010363_3_0_4; -.
DR OrthoDB; 9761531at2; -.
DR Proteomes; UP000005089; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005089};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 265..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 300..322
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 375..394
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 415..435
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 441..464
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 471..490
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 502..520
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 559..754
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 809 AA; 89700 MW; 36BB28A24EA17F1D CRC64;
MLGAIVGFIF GIAWLHQQAT LPNNTVLYGL TAASVILSLL SFIPVVTLRF TVIKPALRFT
AGLAFGVLWS SVFALYGLSR TLPDTLENRD LVITGTVDGL PQPFEEGTRF QFSVEKASAG
SQSVTIPENL MLTWGLKYHR TSLPKVPDIS PGQRWQLNVR LKRPHGNANP DGFDYELWLF
EQGIRATGYV NNDPRLPDKN VLTDSFVSTP MNWVNRVRSV LRERIYRALP NCEYAGVMVA
LVIGDQKAIS QSDWEIFNRT GISHLVAISG LHITMISSLF ALFIGSLWRR SFFTGKQWPL
ILPAQKVAAI AGVLMALAYV ALAGFGVPAR RTLCMIIIVA IALWTGRLTR FSHTLLVAAG
IICLFDPWAL LQPGFWLSFG AVGMILYATS GRTGKMDENP SRLNRFRHSL STAAATQWAV
TIGLVPLTML FFGRISVIGP IANAVAIPLV STVVTPLALI GSILPEPVNA YVLTVAHFLT
RLLAIFLEWL SSFSFAVWTA PAPSFYLILF AMAGTLWMLA PKGWPHRYLG VLCWLPLLLL
TPDHPDYGEA KMTVFDVGQG SSILIETQKH RLLFDTGPVY STDSDAGDRV VIPYLKMRGI
DSLDSIVVSH ADSDHSGGLL TLTRKLPVKT IYSSIAPDST LVQTLPDNRP CIAGQEWDWE
GVRFEMLHPS SDDYLGENNK TNELSCVLKV STSRYSLLLT GDIGKKEEEK LVSRLGEKLK
SDILIAPHHG SNSSSTWPFL FAVKPDYAIY QVGYLNPYRH PDYRAESRYD LLGIKTFRTD
TDGAVGILFG GQISIELYRK KDVRYWRNE
//
