ID C3XAA6_OXAFO Unreviewed; 759 AA.
AC C3XAA6;
DT 16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT 16-JUN-2009, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Diguanylate cyclase (GGDEF) domain protein {ECO:0000313|EMBL:EEO30132.1};
GN ORFNames=OFBG_01160 {ECO:0000313|EMBL:EEO30132.1};
OS Oxalobacter formigenes OXCC13.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Oxalobacteraceae; Oxalobacter.
OX NCBI_TaxID=556269 {ECO:0000313|EMBL:EEO30132.1, ECO:0000313|Proteomes:UP000005089};
RN [1] {ECO:0000313|EMBL:EEO30132.1, ECO:0000313|Proteomes:UP000005089}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OXCC13 {ECO:0000313|EMBL:EEO30132.1,
RC ECO:0000313|Proteomes:UP000005089};
RG The Broad Institute Genome Sequencing Platform;
RA Ward D., Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L.,
RA Berlin A., Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C.,
RA Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A.,
RA Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T.,
RA White J., Yandava C., Allison M.J., Lander E., Nusbaum C., Galagan J.,
RA Birren B.;
RT "The Genome Sequence of Oxalobacter formigenes OXCC13.";
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; GG658170; EEO30132.1; -; Genomic_DNA.
DR AlphaFoldDB; C3XAA6; -.
DR STRING; 847.BRW83_0976; -.
DR eggNOG; COG2199; Bacteria.
DR eggNOG; COG2200; Bacteria.
DR HOGENOM; CLU_000445_70_44_4; -.
DR Proteomes; UP000005089; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd18773; PDC1_HK_sensor; 1.
DR CDD; cd12912; PDC2_MCP_like; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR PANTHER; PTHR33121:SF71; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005089};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 286..305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 346..479
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 488..741
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 759 AA; 86116 MW; 6070C632109CB386 CRC64;
MKEKITRQLA LAIVLLATVL ISVSAYFIYS TKDDIKQQNK QYLSEIAVQN AEVIKNTVRM
ELDKIEAIAN IIGSREKFDV DYALAVLKAE SKRHSFKRLA YVPSDGNAVT TDDVSFNVLG
RSYYKKALAG ESNVSDRLTD KIGGNFINVY AVPLYHKGHI YGVIIATKDT NVLSELLKHN
SFDGEGFSYI ITKDGSPVVN TVHKNSLSSF DNLFDSMRKN HVDENLIAEL KRNMALNKGG
IFENDMSDVP KVLAYSSVGI NDWFVISVVP KQVIAQNADR LINRNVTSAV ITVIVMGALI
FFIVVQNYKN RRKLEQLAYV DSITGGNNFN KFKLLAAEMI ARNKGKNLYM IRIDIDNFKL
LNDMYGFREG DEILVGINQL LSRMDSGRDL HARLSDDNFI WLVNCLTEEE AVSKIRQFND
AFQGTMSQDQ KGYKLGFTFG AYKIHPKNMD VDKIIDRAAM AHQSAKLLHA DPKVVFYDEK
IRNDAIRIKT IENMMYDALA NREFVVYLQP KYNVSTSTIE GAEALVRWVR DGKVIPPSEF
ISIFERNGFI VNMDMYVLEE VCRLQRKWLD MGLNPVPISI NQSKSLVYSK DYVDKLYGVI
TRYDLPARLI EVELLETIIH DNVTELISII RQLRRIGLLI CIDDFGSGYS SLNMLKDFDV
DVLKIDREFL NNAEISERAK YVLAQIITLA KGLKMIVVTE GVETEKQAGL LKELECDTAQ
GFFYARPMPC EQFEKLLSVP GGTRTFESSR EDQLNHELT
//
