ID C3XYH4_BRAFL Unreviewed; 531 AA.
AC C3XYH4;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=TIR domain-containing protein {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=BRAFLDRAFT_94911 {ECO:0000313|EMBL:EEN66859.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN66859.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN66859.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN66859.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
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DR EMBL; GG666473; EEN66859.1; -; Genomic_DNA.
DR RefSeq; XP_002610849.1; XM_002610803.1.
DR AlphaFoldDB; C3XYH4; -.
DR InParanoid; C3XYH4; -.
DR GO; GO:0070513; F:death domain binding; IEA:InterPro.
DR GO; GO:0002020; F:protease binding; IEA:InterPro.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01671; CARD; 1.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR001315; CARD.
DR InterPro; IPR037939; CRADD.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR15034; DEATH DOMAIN-CONTAINING PROTEIN CRADD; 1.
DR PANTHER; PTHR15034:SF7; DEATH DOMAIN-CONTAINING PROTEIN CRADD; 1.
DR Pfam; PF00619; CARD; 1.
DR Pfam; PF13676; TIR_2; 1.
DR SMART; SM00114; CARD; 1.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50209; CARD; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
FT DOMAIN 1..90
FT /note="CARD"
FT /evidence="ECO:0000259|PROSITE:PS50209"
FT DOMAIN 96..226
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT REGION 261..297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 531
FT /evidence="ECO:0000313|EMBL:EEN66859.1"
SQ SEQUENCE 531 AA; 60275 MW; A3560CDF1141B156 CRC64;
MEERHRALLL ANRLEITSDL RFRDIRRRLL DSGTLNGENL DLIENQQTRE DQAKALLDIL
PTRGPTAFAV FREALKHRYP HLARILKDEG QQGPPEAPRV FIIHAGEDKE SFVRPLVATL
QQEGLAEKDV FFDDVSIKPG EVIRDRIIST LSSQSLELVV VVVSTAFLNK PYWPRLEFET
CLKNNKRIFP IWVDANEDSF KAFSELVGKY SPTLKQMSAR RVQRDDVTDE LTNIAAEVVQ
RLSTLRCSTP PPAAIQTLLT LTPFPSSDPS SSDDETSFNR QDMHAAGPSG EQGVDDQIKN
EKEKQLEIAI SRWEKRGHVV KKQLELLKEA EGLLPKETIE SMTKDMLVSN YQSGLHIVDV
KIGCAILHLV PQNMTTLDKF WGDFKSGQLS SNFTDCLITD EMRTLAGEDL AVRVIMLEEQ
YWQWTEYFKG GEMAQTVQKF QSLTVTPGVR ATTWETFAEE YLPDDTEQDL ELNKCNFVTA
TELEAMCDRI KGSWQLTKLN ITVLQAEWND AMGVAIGKLF LKLPSLMELE I
//
