ID C3XYH8_BRAFL Unreviewed; 276 AA.
AC C3XYH8;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=SPRY domain-containing SOCS box protein 4-like isoform X2 {ECO:0000313|RefSeq:XP_035697099.1};
GN Name=LOC118430361 {ECO:0000313|RefSeq:XP_035697099.1};
GN ORFNames=BRAFLDRAFT_60741 {ECO:0000313|EMBL:EEN66863.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN66863.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN66863.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN66863.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
RN [2] {ECO:0000313|RefSeq:XP_035697099.1}
RP IDENTIFICATION.
RC STRAIN=S238N-H82 {ECO:0000313|RefSeq:XP_035697099.1};
RC TISSUE=Testes {ECO:0000313|RefSeq:XP_035697099.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the SPSB family.
CC {ECO:0000256|ARBA:ARBA00010910}.
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DR EMBL; GG666473; EEN66863.1; -; Genomic_DNA.
DR RefSeq; XP_002610853.1; XM_002610807.1.
DR RefSeq; XP_035697099.1; XM_035841206.1.
DR STRING; 7739.C3XYH8; -.
DR eggNOG; KOG3953; Eukaryota.
DR InParanoid; C3XYH8; -.
DR OMA; SESYGWD; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000001554; Chromosome 14.
DR GO; GO:0019005; C:SCF ubiquitin ligase complex; IBA:GO_Central.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd03718; SOCS_SSB1_4; 1.
DR CDD; cd12906; SPRY_SOCS1-2-4; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 1.10.750.20; SOCS box; 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR InterPro; IPR003877; SPRY_dom.
DR PANTHER; PTHR12245:SF11; PROTEIN GUSTAVUS; 1.
DR PANTHER; PTHR12245; SPRY DOMAIN CONTAINING SOCS BOX PROTEIN; 1.
DR Pfam; PF07525; SOCS_box; 1.
DR Pfam; PF00622; SPRY; 1.
DR SMART; SM00969; SOCS_box; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50225; SOCS; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001554}.
FT DOMAIN 37..234
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT DOMAIN 236..276
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 276 AA; 31029 MW; D3E2C8DCAD25A425 CRC64;
MGQKVSGGVK TAGPGREPSL KALNSDRDLL HPDMQKPSRL DMLLDMPQAD RETQVKHAWN
NEDRSLNIFV KEDDKLTFHR HPVAQSTDCI RGKVGYTRGL HVWEIHWSTR QRGTHAVVGV
ATEHAALHSV GYQSLVGSNA ESWGWDLGRN KLYHDSKNNP GITYPRTLKA DENFVVPDKF
LVVLDMDEGT ISFVVDGQFL GIAFRGLKGK KLYPIVSAVW GHCEITTKYI GGLDPEPLPL
MDLCRRTIRL SLGKDRLKDV PKLPLPQALK NYLLYQ
//
