ID   C3Y4Z5_BRAFL            Unreviewed;       193 AA.
AC   C3Y4Z5;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   RecName: Full=Medium-chain acyl-CoA ligase ACSF2, mitochondrial {ECO:0000256|ARBA:ARBA00039638};
GN   ORFNames=BRAFLDRAFT_92400 {ECO:0000313|EMBL:EEN64528.1};
OS   Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC   Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC   Branchiostomatidae; Branchiostoma.
OX   NCBI_TaxID=7739;
RN   [1] {ECO:0000313|EMBL:EEN64528.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN64528.1};
RC   TISSUE=Testes {ECO:0000313|EMBL:EEN64528.1};
RX   PubMed=18563158; DOI=10.1038/nature06967;
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA   Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA   Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA   Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA   Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA   Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA   Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA   Satoh N., Rokhsar D.S.;
RT   "The amphioxus genome and the evolution of the chordate karyotype.";
RL   Nature 453:1064-1071(2008).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + CoA + octanoate = AMP + diphosphate + octanoyl-CoA;
CC         Xref=Rhea:RHEA:33631, ChEBI:CHEBI:25646, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:33019, ChEBI:CHEBI:57287, ChEBI:CHEBI:57386,
CC         ChEBI:CHEBI:456215; Evidence={ECO:0000256|ARBA:ARBA00035758};
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a medium chain fatty acid + ATP + CoA = a medium-chain fatty
CC         acyl-CoA + AMP + diphosphate; Xref=Rhea:RHEA:48340,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:57287,
CC         ChEBI:CHEBI:59558, ChEBI:CHEBI:90546, ChEBI:CHEBI:456215; EC=6.2.1.2;
CC         Evidence={ECO:0000256|ARBA:ARBA00036216};
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DR   EMBL; GG666487; EEN64528.1; -; Genomic_DNA.
DR   RefSeq; XP_002608518.1; XM_002608472.1.
DR   AlphaFoldDB; C3Y4Z5; -.
DR   STRING; 7739.C3Y4Z5; -.
DR   eggNOG; KOG1177; Eukaryota.
DR   InParanoid; C3Y4Z5; -.
DR   Gene3D; 3.40.50.980; -; 1.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   PANTHER; PTHR43201; ACYL-COA SYNTHETASE; 1.
DR   PANTHER; PTHR43201:SF5; MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
PE   4: Predicted;
FT   DOMAIN          88..165
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
SQ   SEQUENCE   193 AA;  21669 MW;  881E231483557DF0 CRC64;
     MAFGWRSAES AGVRLLHPNV LKCSKHSALN GNSGMGRLVV GWCSARSASV RLVFGNLRVY
     FFTANTMSYM RGATDDPLLD VTFGQLLDDT AARWPDREAY VFKKTGSRVT FADIQEKATR
     LAAGLKAIGT ARGDVVAWLF GHRPEWIYLY FAVAKLGAIA FPLQEERVGR SVETMNYFLN
     KVMMIVCRWR ILY
//