ID C3Y8I7_BRAFL Unreviewed; 379 AA.
AC C3Y8I7;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=Uncharacterized oxidoreductase YrbE-like {ECO:0000313|RefSeq:XP_035678869.1};
GN Name=LOC118417417 {ECO:0000313|RefSeq:XP_035678869.1};
GN ORFNames=BRAFLDRAFT_69830 {ECO:0000313|EMBL:EEN63424.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN63424.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN63424.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN63424.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
RN [2] {ECO:0000313|RefSeq:XP_035678869.1}
RP IDENTIFICATION.
RC STRAIN=S238N-H82 {ECO:0000313|RefSeq:XP_035678869.1};
RC TISSUE=Testes {ECO:0000313|RefSeq:XP_035678869.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the Gfo/Idh/MocA family.
CC {ECO:0000256|ARBA:ARBA00010928}.
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DR EMBL; GG666491; EEN63424.1; -; Genomic_DNA.
DR RefSeq; XP_002607414.1; XM_002607368.1.
DR RefSeq; XP_035678869.1; XM_035822976.1.
DR STRING; 7739.C3Y8I7; -.
DR KEGG; bfo:118417417; -.
DR eggNOG; KOG2741; Eukaryota.
DR InParanoid; C3Y8I7; -.
DR OMA; FLERYMQ; -.
DR OrthoDB; 1992171at2759; -.
DR Proteomes; UP000001554; Chromosome 6.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IBA:GO_Central.
DR GO; GO:0006740; P:NADPH regeneration; IBA:GO_Central.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR004104; Gfo/Idh/MocA-like_OxRdtase_C.
DR InterPro; IPR000683; Gfo/Idh/MocA-like_OxRdtase_N.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR42840:SF3; BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G10240)-RELATED; 1.
DR PANTHER; PTHR42840; NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED; 1.
DR Pfam; PF01408; GFO_IDH_MocA; 1.
DR Pfam; PF02894; GFO_IDH_MocA_C; 1.
DR SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000001554}.
FT DOMAIN 17..134
FT /note="Gfo/Idh/MocA-like oxidoreductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01408"
FT DOMAIN 149..344
FT /note="Gfo/Idh/MocA-like oxidoreductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02894"
FT REGION 350..379
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 379 AA; 41734 MW; 67E85E5D5F70A0D8 CRC64;
MPGHMNRTKA SKKIPLALFG LGRAGNIHAG NIEKNPHCRL KYLVDEDVER CHRFVEEFMS
EAVVVKASEA DVVYNDPEVQ GIVVTSPTFT HPDICLKALK AGKDALCEKP VAADMKTTAL
VYDEAEKQGR ILLCAFNRRF DPALLNLEER VKKGEVGQIH RFKTSSRDSP LPSIEYLRIS
GGIFHDCAVH DIDECLWIMK ELPTQVHTMA HCFTPAIAEL DDVDTVSITM KFPSGAIASL
DLSRLSTYGY DQRTEVYGSK GMLLNHNTTP TGLHHSNGSG ETAQPIHHSF PQRYAASYRG
ELVHFLNLIQ GLEEPRIVKK DTLLSSHIAE ACEESHRTGQ AVSLSYDHLL TSPPAHEKGG
TTDVGSVPME QDANAVATA
//
