ID   C3YP91_BRAFL            Unreviewed;      1118 AA.
AC   C3YP91;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   27-MAR-2024, entry version 58.
DE   RecName: Full=Death domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=BRAFLDRAFT_94541 {ECO:0000313|EMBL:EEN57982.1};
OS   Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC   Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC   Branchiostomatidae; Branchiostoma.
OX   NCBI_TaxID=7739;
RN   [1] {ECO:0000313|EMBL:EEN57982.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN57982.1};
RC   TISSUE=Testes {ECO:0000313|EMBL:EEN57982.1};
RX   PubMed=18563158; DOI=10.1038/nature06967;
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA   Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA   Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA   Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA   Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA   Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA   Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA   Satoh N., Rokhsar D.S.;
RT   "The amphioxus genome and the evolution of the chordate karyotype.";
RL   Nature 453:1064-1071(2008).
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DR   EMBL; GG666537; EEN57982.1; -; Genomic_DNA.
DR   RefSeq; XP_002601970.1; XM_002601924.1.
DR   AlphaFoldDB; C3YP91; -.
DR   eggNOG; ENOG502SEC4; Eukaryota.
DR   InParanoid; C3YP91; -.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd01670; Death; 1.
DR   Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR000488; Death_domain.
DR   InterPro; IPR025307; FIIND_dom.
DR   PANTHER; PTHR10454; CASPASE; 1.
DR   PANTHER; PTHR10454:SF220; DED DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00531; Death; 1.
DR   Pfam; PF13553; FIIND; 1.
DR   Pfam; PF20706; GT4-conflict; 1.
DR   SUPFAM; SSF47986; DEATH domain; 1.
DR   PROSITE; PS50017; DEATH_DOMAIN; 1.
DR   PROSITE; PS51830; FIIND; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490}.
FT   DOMAIN          463..534
FT                   /note="Death"
FT                   /evidence="ECO:0000259|PROSITE:PS50017"
FT   DOMAIN          559..835
FT                   /note="FIIND"
FT                   /evidence="ECO:0000259|PROSITE:PS51830"
FT   REGION          19..59
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          81..153
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          167..222
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1097..1118
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        29..59
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        81..127
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        138..153
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        167..185
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1118 AA;  125729 MW;  C736079F1E7AAB94 CRC64;
     MESDFVQEKT GHRCKVCRLS VRGHPGPYGR GKCKFERREG SSDEEYFKQQ RGSAHVEEKL
     RSLRRDSKVS DLVRAVWSDS ISMDTDETQV RQSSSHNLKK SSGYSRENAS TRARSESPAV
     QFSRHRARNV STSREAGPAR PEKPDIRDLR KSRALVRKVD KALDELLDSD TSRGKQPRSK
     RYEDRGSVSS LSQSDSTESD FMRKLRRRQR RRGSRGKSCK MKGERVSSKL FISRRRWDSY
     DSDTSGPLVV LLHAAQDGEF VRRLVEKLRD LGAGYSLPQT DIPCQQVTGT PGDVSRAQLT
     STLTHGSVKL VVPVISRHLL ADQSSLTVGL ETAVRNNKPR YVIWLDQNKD DFREFGTLVS
     RQYPTLEAPA RRVQRDRIEK TMPGSGFSWM DGIAWDVRDA LCRQTGVLRW PCLTALDLTR
     SFLADNMNLP AVLARLEQEN QLSPAAVRDI QVSRAVGEER QLWTRLGQEL GLNRTVLDNI
     RRDYYFGNTK MAFQMLKAWR TKTPHGPLHY LPQLEETLQN MGKPDLAAAV QGVYKEYCDA
     LPLQEVSPEM TGDTLWSLRL PGEGKYLCRR TDLGMVTPYP LCHTCEGKYL CRRTDLGVVT
     SYPLHVTYRS ANWSDNWQQV GEWMPLGPLF SIQCEDVEGP VDILLPHVLC LTDVSELTPA
     DIQVVHVVGD SPELLPVTEL TPSHAVTRFK KGSLFGVVGR TAKVLGISRN GLLTAFAAVN
     DSDISTLKVY IVSNTTIMHE CLMFEDTFDT NKFYEPFRVE VTSDIWNSST TSRLTLELLK
     EVNNDAKEPV AELTLGHYKR GNTAEGVDSG LSTPTELEKY LESLDIAGRG SILLVGDEYC
     TSKGGISTIN RQVAHMITAA GAKVYATVLE ASQQEERDAE RDGVRLLKPR LDVDSSAKPS
     LEWLTVYHKH HFPHIPSDIS CIVGHVDVTS RAARKIKEER FPHAKLVMFG HVAPEETEHY
     KSDEKALGVG RKEASIQDDI GKADVVFSVG PRIHRHYDRF LHQCGVDHYI FLPEPSKVFS
     EAKMTFGEED EAEKPERVVL SIGRVRNVEM LKEKWADAIE DFITNARSEF AEARAFREKL
     LASKYWEESH QTFLQASGIT ASPSAQAEGG DAEAGDPN
//