ID C3YV67_BRAFL Unreviewed; 382 AA.
AC C3YV67;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 71.
DE RecName: Full=Splicing factor 45 {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=BRAFLDRAFT_205776 {ECO:0000313|EMBL:EEN55783.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN55783.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN55783.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN55783.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
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DR EMBL; GG666556; EEN55783.1; -; Genomic_DNA.
DR RefSeq; XP_002599771.1; XM_002599725.1.
DR AlphaFoldDB; C3YV67; -.
DR STRING; 7739.C3YV67; -.
DR eggNOG; KOG1996; Eukaryota.
DR InParanoid; C3YV67; -.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000380; P:alternative mRNA splicing, via spliceosome; IBA:GO_Central.
DR GO; GO:0045292; P:mRNA cis splicing, via spliceosome; IEA:InterPro.
DR CDD; cd12647; RRM_UHM_SPF45; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR000467; G_patch_dom.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR040052; RBM17.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR003954; RRM_dom_euk.
DR InterPro; IPR034653; SPF45_RRM.
DR PANTHER; PTHR13288:SF8; SPLICING FACTOR 45; 1.
DR PANTHER; PTHR13288; SPLICING FACTOR 45 SPF45; 1.
DR Pfam; PF01585; G-patch; 1.
DR Pfam; PF00076; RRM_1; 1.
DR PIRSF; PIRSF031066; Splicing_factor_SPF45; 1.
DR SMART; SM00443; G_patch; 1.
DR SMART; SM00361; RRM_1; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50174; G_PATCH; 1.
DR PROSITE; PS50102; RRM; 1.
PE 4: Predicted;
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 212..252
FT /note="G-patch"
FT /evidence="ECO:0000259|PROSITE:PS50174"
FT DOMAIN 286..364
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 49..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 97..210
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..63
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 97..124
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 172..195
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EEN55783.1"
SQ SEQUENCE 382 AA; 41636 MW; BBE5C9FBD2585F0B CRC64;
GWSSSIKLLQ SQLALKKAAL TQAQRQKART ATVAPVVALG SAKVKEELAE ASSSSSGKVS
IDPSQMPASI PGEEALINVI DEYDPLFPND YEKVAKEFRE KQARERDQER DRDVDERDSR
KPSRGGGSFP HGFDSTHAAR GPSGSSDDPP EERKPRSRYG AAIAPPPSLQ DDEPPFERKP
RSSKHGDEER DPERATTPPP GSSFAATIGG SGGLAASRIM AKYGYREGQG LGKSEQGIST
ALQVEKTSKR GGKIIQGTLE PKGTIKYHLV KPELDSITEI MKNPTKVVVL RNMVGPGEVD
DDLEPETAEE CAKYGKVNKV VIFEMPGRPE DEAVRIFVEF DRLEAAIKAV VDLNGRYFGG
RLVKGAFYSL DKFRTLQLAD EI
//
