ID C3ZE01_BRAFL Unreviewed; 474 AA.
AC C3ZE01;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE RecName: Full=Cytochrome P450 {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=BRAFLDRAFT_201594 {ECO:0000313|EMBL:EEN48957.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN48957.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN48957.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN48957.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|ARBA:ARBA00001971};
CC -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
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DR EMBL; GG666612; EEN48957.1; -; Genomic_DNA.
DR RefSeq; XP_002592946.1; XM_002592900.1.
DR AlphaFoldDB; C3ZE01; -.
DR STRING; 7739.C3ZE01; -.
DR eggNOG; KOG0158; Eukaryota.
DR InParanoid; C3ZE01; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR GO; GO:0008395; F:steroid hydroxylase activity; IBA:GO_Central.
DR Gene3D; 1.10.630.10; Cytochrome P450; 2.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR PANTHER; PTHR24302; CYTOCHROME P450 FAMILY 3; 1.
DR PANTHER; PTHR24302:SF15; FATTY-ACID PEROXYGENASE; 1.
DR Pfam; PF00067; p450; 2.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|ARBA:ARBA00022617, ECO:0000256|RuleBase:RU000461};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|RuleBase:RU000461};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|RuleBase:RU000461};
KW Monooxygenase {ECO:0000256|RuleBase:RU000461};
KW Oxidoreductase {ECO:0000256|RuleBase:RU000461};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 213..236
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT NON_TER 474
FT /evidence="ECO:0000313|EMBL:EEN48957.1"
SQ SEQUENCE 474 AA; 52768 MW; C9C9A25FCC8FB92F CRC64;
MLDLLPFSPT WVLVGLCAVL LYLYMVWPYS TFNDLGIPGP KPVPLFGNYL SYGQGIAKFD
KECYKKFNKV YGIFEGRQPI LIVGDLELVK DITVKEANTF TNRRVKGQGE FFDGGLLNIK
DADWKRVRSA ISPTFSSGKL KQMALVVEKC GDNFVANLEN NAKQGVMFDL KDLSGAFTMD
VISGTAFGVD VDSLHDPNHP FVANARKLFD FNLFNPILIV LFLFPQLAKI FSAMGLNMSV
FSTKALEFFG AAVDNVLDMR GSNEEEAAKR VDFLQLMLKA HNEELDKEMP KDVEIKSNAV
LFWIAGYETT ANTISLTAYN LALHQEAQDK VIEEVDAVIE KRVSPKSNLT TRTPATTHVT
NSNMMAFCAT GNNFPPMHQK SSQWCVSFRT HSAKSAPKTA KMPPAMFSKE EKESRDPYAY
LPFGSGPRNC VGMRLALMEL KFALAKALQK VRFVTCDKTV VSILLDEASS LKAE
//
