ID C4IHC6_CLOBU Unreviewed; 463 AA.
AC C4IHC6;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Glutamate synthase (NADPH), homotetrameric {ECO:0000313|EMBL:EEP53677.1};
DE EC=1.4.1.13 {ECO:0000313|EMBL:EEP53677.1};
GN Name=gltA {ECO:0000313|EMBL:EEP53677.1};
GN ORFNames=CLP_3087 {ECO:0000313|EMBL:EEP53677.1};
OS Clostridium butyricum E4 str. BoNT E BL5262.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=632245 {ECO:0000313|EMBL:EEP53677.1, ECO:0000313|Proteomes:UP000003081};
RN [1] {ECO:0000313|EMBL:EEP53677.1, ECO:0000313|Proteomes:UP000003081}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E4 str. BoNT E BL5262 {ECO:0000313|Proteomes:UP000003081};
RA Shrivastava S., Brinkac L.B., Brown J.L., Bruce D.B., Detter C.,
RA Green L.D., Munk C.A., Rogers Y.C., Tapia R., Sims D.R., Smith L.A.,
RA Smith T.J., Sutton G., Brettin T.;
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEP53677.1}.
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DR EMBL; ACOM01000005; EEP53677.1; -; Genomic_DNA.
DR RefSeq; WP_002579302.1; NZ_ACOM01000005.1.
DR AlphaFoldDB; C4IHC6; -.
DR STRING; 1492.ATN24_05980; -.
DR eggNOG; COG0493; Bacteria.
DR HOGENOM; CLU_000422_3_3_9; -.
DR Proteomes; UP000003081; Unassembled WGS sequence.
DR GO; GO:0004355; F:glutamate synthase (NADPH) activity; IEA:UniProtKB-EC.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR028261; DPD_II.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR009051; Helical_ferredxn.
DR InterPro; IPR006004; SudA-like.
DR NCBIfam; TIGR01316; gltA; 1.
DR PANTHER; PTHR43100; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR PANTHER; PTHR43100:SF1; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR Pfam; PF14691; Fer4_20; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR PRINTS; PR00419; ADXRDTASE.
DR SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR SUPFAM; SSF51971; Nucleotide-binding domain; 2.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:EEP53677.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000003081}.
FT DOMAIN 20..130
FT /note="Dihydroprymidine dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF14691"
FT DOMAIN 143..450
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
SQ SEQUENCE 463 AA; 49575 MW; 327A569AD07B8881 CRC64;
MDMNERLIRV PVREQDPKVR ATNFEEVCLG YNEEEAVKEA SRCLNCKNAQ CRKGCPVSID
IPAFIAKLKE SDFEGAAKEI AKYSALPAVC GRVCPQEKQC EGKCVLGIKG ESVSIGKLER
FTADWAAAHN VDLSATEPKK GIKVAVIGSG PAGLTCAGDL AKKGYEVTIF EALHKAGGVL
EYGIPEFRLP KEKVVANEVN NIKKLGVKIE TNVIIGRTIT IEELFEEEGF EAVFIGSGAG
LPRFMGIPGE NANGVFSANE FLTRVNLMKA AVEGYETPVR SGKKVAVVGG GNVAMDAART
ALRLGSESHI VYRRGESELP ARAEEVHHAK EEGVIFDVLT NPTEILVDEN GWVKGMKCVR
MELGEPDASG RRSPVEIPGS EFVMDVDTVI MSLGTSPNPL ISSTTEGLEI NKRRCIVAEE
ETGLTTKEGV YAGGDAVTGA ATVILAMGAG KKAAAAIDEY LQK
//
