ID C4ILN0_CLOBU Unreviewed; 446 AA.
AC C4ILN0;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Transcriptional regulator, GntR family/aminotransferase, classes I and II {ECO:0000313|EMBL:EEP52812.1};
GN ORFNames=CLP_0058 {ECO:0000313|EMBL:EEP52812.1};
OS Clostridium butyricum E4 str. BoNT E BL5262.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=632245 {ECO:0000313|EMBL:EEP52812.1, ECO:0000313|Proteomes:UP000003081};
RN [1] {ECO:0000313|EMBL:EEP52812.1, ECO:0000313|Proteomes:UP000003081}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E4 str. BoNT E BL5262 {ECO:0000313|Proteomes:UP000003081};
RA Shrivastava S., Brinkac L.B., Brown J.L., Bruce D.B., Detter C.,
RA Green L.D., Munk C.A., Rogers Y.C., Tapia R., Sims D.R., Smith L.A.,
RA Smith T.J., Sutton G., Brettin T.;
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEP52812.1}.
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DR EMBL; ACOM01000007; EEP52812.1; -; Genomic_DNA.
DR RefSeq; WP_003408057.1; NZ_ACOM01000007.1.
DR AlphaFoldDB; C4ILN0; -.
DR eggNOG; COG1167; Bacteria.
DR HOGENOM; CLU_017584_0_0_9; -.
DR Proteomes; UP000003081; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW Aminotransferase {ECO:0000313|EMBL:EEP52812.1};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000003081};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000313|EMBL:EEP52812.1}.
FT DOMAIN 1..69
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 446 AA; 52062 MW; 6FD92951E900BDFC CRC64;
MKIYERILED IKKYIIDEKV PQGFKLPSIN YMCEKYNCSK GTVIKAYDSL CSEHIIYATP
QKGFFVADNL VRYNNDNSGS YDLSTGNPVV SSIPVKDIQH CLNSAVELYS DISLAMTSKG
IPSVLKILPE ILNKSDIYCK NKNIYLSQGV LQVLTLLSKM PFPNGNDTIL IEEPSYVYYI
DFLRHENLEV KTIKRDENGI NIKELEEIFK NEKIKFFYTI PRNHNPLGTY YSVRQRKSII
ELAHKYNVYV VEDDYFSDVY SLPNYSPIYY YSDFKNCIYL KSYSKTIPYI RIGAAVIPDD
LIDRYEEWIK YSYYSSYYMP SLVSQATFES YIKSNIYEKH IKIIDKHLKE LLSIFRSVTA
KWDSNIVKVI GGKSGYYSTM ILNSKISSKE LIDRLKKRNI YASSNKRAYY NKENYDNSIR
ISLARLNKNE VKVVLEIIYE EILTLM
//
