ID C4IME0_CLOBU Unreviewed; 574 AA.
AC C4IME0;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Hydrogenase-1 {ECO:0000313|EMBL:EEP52487.1};
GN ORFNames=CLP_4204 {ECO:0000313|EMBL:EEP52487.1};
OS Clostridium butyricum E4 str. BoNT E BL5262.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=632245 {ECO:0000313|EMBL:EEP52487.1, ECO:0000313|Proteomes:UP000003081};
RN [1] {ECO:0000313|EMBL:EEP52487.1, ECO:0000313|Proteomes:UP000003081}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E4 str. BoNT E BL5262 {ECO:0000313|Proteomes:UP000003081};
RA Shrivastava S., Brinkac L.B., Brown J.L., Bruce D.B., Detter C.,
RA Green L.D., Munk C.A., Rogers Y.C., Tapia R., Sims D.R., Smith L.A.,
RA Smith T.J., Sutton G., Brettin T.;
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEP52487.1}.
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DR EMBL; ACOM01000009; EEP52487.1; -; Genomic_DNA.
DR RefSeq; WP_002583070.1; NZ_ACOM01000009.1.
DR AlphaFoldDB; C4IME0; -.
DR SMR; C4IME0; -.
DR STRING; 1492.ATN24_01590; -.
DR GeneID; 66379940; -.
DR eggNOG; COG3383; Bacteria.
DR eggNOG; COG4624; Bacteria.
DR HOGENOM; CLU_018240_2_1_9; -.
DR Proteomes; UP000003081; Unassembled WGS sequence.
DR GO; GO:0008901; F:ferredoxin hydrogenase activity; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR CDD; cd00207; fer2; 1.
DR Gene3D; 3.10.20.740; -; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 3.40.50.1780; -; 1.
DR Gene3D; 4.10.260.20; Iron hydrogenase, small subunit; 1.
DR InterPro; IPR036010; 2Fe-2S_ferredoxin-like_sf.
DR InterPro; IPR001041; 2Fe-2S_ferredoxin-type.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR009016; Fe_hydrogenase.
DR InterPro; IPR004108; Fe_hydrogenase_lsu_C.
DR InterPro; IPR003149; Fe_hydrogenase_ssu.
DR InterPro; IPR036991; Fe_hydrogenase_ssu_sf.
DR InterPro; IPR013352; Fe_hydrogenase_subset.
DR NCBIfam; TIGR02512; FeFe_hydrog_A; 1.
DR NCBIfam; NF040762; Hydr_FeFe_Clost; 1.
DR PANTHER; PTHR11615:SF6; NADH-UBIQUINONE OXIDOREDUCTASE 75 KDA SUBUNIT, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11615; NITRATE, FORMATE, IRON DEHYDROGENASE; 1.
DR Pfam; PF02906; Fe_hyd_lg_C; 1.
DR Pfam; PF02256; Fe_hyd_SSU; 1.
DR Pfam; PF13510; Fer2_4; 1.
DR Pfam; PF12838; Fer4_7; 1.
DR SMART; SM00902; Fe_hyd_SSU; 1.
DR SUPFAM; SSF54292; 2Fe-2S ferredoxin-like; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF53920; Fe-only hydrogenase; 1.
DR PROSITE; PS51085; 2FE2S_FER_2; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000003081}.
FT DOMAIN 1..78
FT /note="2Fe-2S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51085"
FT DOMAIN 138..167
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 181..210
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 574 AA; 63055 MW; A41E635DBCBD6091 CRC64;
MINLIIDEKN VQVPEGTSII QAALDNGIDI PSLCYLKECS NVGKCGVCAV EVEGKKVLSL
ACLTKVEEGM VVRTNTEATQ ERVKMRVAAL LDKHEFKCGP CPRRETCEFL KLVIKTKAKA
NKPFLPTDKT EFLDDRSKSI TIDRSKCVLC GRCVAACKEK TGTGNIEISG KGPDRKVQAI
EGKCFDETNC LLCGQCVAAC PVAALNEKPH IDRVKEALED PNKHVIVAMA PAVRTSMGEL
FKMGYGVDVT GKLYSSLRQL GFDKVFDINF GADMTIMEEA TEFIERINNN GPFPMFTSCC
PAWVRQAENY YPELLGNLSS AKSPQQIFGA ASKTYYPTVE GLDPKSVYTV TIMPCTAKKY
EADRTEMENE GLRNIDAVLT TRELAKMIKD AKINFATLED EKADPAMGEY TGAGVIFGAT
GGVMEAALRT AKDFVEDKDL IDIEYKQVRG LDGIKEATVE IGGKNYNVAV INGSANLTKF
VEGGQMDEKQ YHFVEVMSCP GGCVNGGGQP HVAAKDRDTA NVRAVRASVL YNQDKTAVKR
KSHKNEALMK MYNEYMGMPG QHKAHELLHL KYTK
//
