ID   C4JNQ8_UNCRE            Unreviewed;       838 AA.
AC   C4JNQ8;
DT   07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   07-JUL-2009, sequence version 1.
DT   27-MAR-2024, entry version 62.
DE   RecName: Full=RFX-type winged-helix domain-containing protein {ECO:0000259|PROSITE:PS51526};
GN   ORFNames=UREG_04378 {ECO:0000313|EMBL:EEP79532.1};
OS   Uncinocarpus reesii (strain UAMH 1704).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenaceae; Uncinocarpus.
OX   NCBI_TaxID=336963 {ECO:0000313|EMBL:EEP79532.1, ECO:0000313|Proteomes:UP000002058};
RN   [1] {ECO:0000313|Proteomes:UP000002058}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UAMH 1704 {ECO:0000313|Proteomes:UP000002058};
RX   PubMed=19717792; DOI=10.1101/gr.087551.108;
RA   Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA   Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA   McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA   Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA   Henn M.R., Birren B.W., Taylor J.W.;
RT   "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT   and their relatives.";
RL   Genome Res. 19:1722-1731(2009).
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DR   EMBL; CH476616; EEP79532.1; -; Genomic_DNA.
DR   RefSeq; XP_002544861.1; XM_002544815.1.
DR   AlphaFoldDB; C4JNQ8; -.
DR   STRING; 336963.C4JNQ8; -.
DR   GeneID; 8438364; -.
DR   KEGG; ure:UREG_04378; -.
DR   VEuPathDB; FungiDB:UREG_04378; -.
DR   eggNOG; KOG3712; Eukaryota.
DR   HOGENOM; CLU_011526_0_1_1; -.
DR   InParanoid; C4JNQ8; -.
DR   OMA; MIWLREN; -.
DR   OrthoDB; 5489658at2759; -.
DR   Proteomes; UP000002058; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR003150; DNA-bd_RFX.
DR   InterPro; IPR039779; RFX-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR12619; RFX TRANSCRIPTION FACTOR FAMILY; 1.
DR   PANTHER; PTHR12619:SF5; RFX, ISOFORM H; 1.
DR   Pfam; PF02257; RFX_DNA_binding; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS51526; RFX_DBD; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002058}.
FT   DOMAIN          240..314
FT                   /note="RFX-type winged-helix"
FT                   /evidence="ECO:0000259|PROSITE:PS51526"
FT   REGION          1..62
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          179..201
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          318..358
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          754..792
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        11..25
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        26..62
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        322..343
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        344..358
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   838 AA;  93676 MW;  0D878345398EAEC0 CRC64;
     MVPDTGRDPF PPQRGQKRTR SRQGTAEPGR SRSNTAASKF SRPPRSRGST ASIQSCSTQY
     MPEQQVPEGY EPYMRSQFGS SQPVYHGNPE EMIMRFGDQL ANSDAGTLLD PALQENHNSA
     KPRMDVHYQN PDMSVHNPTA HGLPADLSHH GMTGEMHPVH YPNLFDGVEN QIPDHLLEEH
     EGSEQGPRKK RGTSSSIAND NELRRLLRQY DGYTLHQMAM EVQKHEGAGG KSEKVKQVFA
     MIWLRENCRK STGSVRRDRV YCCYAEKCGT ERVSVLNPAS FGKLVRIIFP NVQTRRLGVR
     GESKYHYVDL SIIISEPKPD VNSTESGDKA TETTGEDSQE GYTKEKSVNP THSPLETTSR
     LLNDTRSSHA PSGSLSHHHC GCHSPYTPQP GSISDVDFSA MTAQEKLHLL LHFGIDESPA
     VDNETLRLPS IHGYLPPGSD SDVADALMAL YRSHSISVID SFRFCKEKNF FRHISAFQGT
     LTVPVHKLLV HPAIVPWIEE CDWLMYQKMV AFIAPLTTQV IPEPVVKAFT SISRRLVPHI
     EDTFKSQPEH VSSARIVPAR LFCHLLRRML DVNQCANSAA AWLCHIENRT KMWEEFQSFL
     DITDMVCKAR IPRCSLKGVV DIFKEHVKSL LGPLDQSGAE VELYDHDLGF RKFTYSTTEG
     REYTSFPDRW ISFILRLPEL FPGHAPQCII DKADAMWTSI LHRFTLEGAE SFSAWWMTKV
     FFMEMIQWQA EKGGFMHYSP KTLHQFLATA ETDAESATQS STLAPEQSNE ASSSAATNKN
     ESTTTTADDS TLMAGRASLN NDDSAIALDE DSLLLSGSKY AEITVSDPAD AEGEVVVV
//